RMDN3 - regulator of microtubule dynamics 3 Gene

Homo sapiens

Also known as RMD3; RMD-3; FAM82C; FAM82A2; ptpip51

Gene ID: 55177 | Gene type: protein coding

About RMDN3

Cytogenetic location: 15q15.1 Genomic coordinates (GRCh38): 15:40,735,887-40,755,254 (from NCBI)

This gene has 11 transcripts (splice variants), 217 orthologues and 3 paralogues. Ubiquitous expression in small intestine (RPKM 16.9), lung (RPKM 14.6) and 25 other tissues.

Summary

Enables microtubule binding activity. Involved in cellular calcium ion homeostasis. Located in several cellular components, including intercellular bridge; mitochondrial outer membrane; and spindle. [provided by Alliance of Genome Resources, Apr 2022]

RMDN3 Products(6)

mRNA	Protein	Name
NM_001304802.2	NP_001291731.1	regulator of microtubule dynamics protein 3 isoform 1
NM_001323894.2	NP_001310823.1	regulator of microtubule dynamics protein 3 isoform 1
NM_001323895.2	NP_001310824.1	regulator of microtubule dynamics protein 3 isoform 2
NM_001323896.2	NP_001310825.1	regulator of microtubule dynamics protein 3 isoform 3
NM_001323897.2	NP_001310826.1	regulator of microtubule dynamics protein 3 isoform 3
NM_018145.3	NP_060615.1	regulator of microtubule dynamics protein 3 isoform 1

Protein Preferred Names

Protein Names

regulator of microtubule dynamics protein 3

TCPTP-interacting protein 51

Related Diseases

Diseases

Alias

Amyotrophic Lateral Sclerosis 8

Amyotrophic Lateral Sclerosis Type 8	ALS8
Sclerosis, Lateral, Amyotrophic, Type Type 8

Amyotrophic Lateral Sclerosis 16, Juvenile

Amyotrophic Lateral Sclerosis Type 16	ALS16
Amyotrophic Lateral Sclerosis 16	Sclerosis, Lateral, Amyotrophic, Type 16, Juvenile

Alzheimer Disease 7

Ad7	Alzheimer'S Disease 7
Alzheimer Disease, Familial, 7	Alzheimer Disease-7
Alzheimer Disease, Familial 7

Hereditary Spastic Paraplegia

Familial Spastic Paraplegia	Hereditary Spastic Paraparesis
Strumpell-Lorrain Disease	Familial Spastic Paraparesis
Hsp	Spg
Strümpell-Lorrain Disease	Spastic Paraplegia, Hereditary
French Settlement Disease	Strumpell-Lorrain Syndrome
Fsp	Spastic Paraplegia, Familial
Spastic Paraplegia Hereditary	Spastic Paraplegia 3, Autosomal Dominant
Spastic Paraparesis	Hereditary Spastic Paralysis
Familial Spastic Paralysis	Hereditary Spastic Ataxia

Amyotrophic Lateral Sclerosis 1

Amyotrophic Lateral Sclerosis	ALS
Lou Gehrig Disease	Amyotrophic Lateral Sclerosis Type 1
Charcot Disease	ALS1
Amyotrophic Lateral Sclerosis, Susceptibility To	Fals
Lou Gehrig'S Disease	Mnd
Motor Neuron Disease	Familial Amyotrophic Lateral Sclerosis
Amyotrophic Lateral Sclerosis 1, Familial	Amyotrophic Lateral Sclerosis 1, Autosomal Dominant
Motor Neuron Disease, Bulbar	Motor Neurone Disease
Amyotrophic Lateral Sclerosis With Dementia	Dementia With Amyotrophic Lateral Sclerosis
Motor Neuron Disease, Amyotrophic Lateral Sclerosis	Sclerosis, Lateral, Amyotrophic
Sclerosis, Lateral, Amyotrophic, Type 1	Amyotrophic Sclerosis
Als - [Amyotrophic Lateral Sclerosis]	Wasting Palsy
Amyotrophic Paralysis	Amyotrophy Lateral Sclerosis
Wasting Paralysis	Spinal Progressive Amyotrophy
Progressive Atrophic Paralysis

Charcot-Marie-Tooth Disease

Cmt	Hmsn
Hereditary Motor And Sensory Neuropathy	Pma
Cmt - Charcot-Marie-Tooth Disease	Charcot Marie Tooth Disease
Charcot-Marie-Tooth Hereditary Neuropathy	Charcot-Marie-Tooth Syndrome
Peroneal Muscular Atrophy	Hereditary Motor And Sensory Neuropathies

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS12013	RMDN3 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	RMDN3	VGNC	VGNC:64651
Macaca mulatta	RMDN3	VGNC	VGNC:76821
Rattus norvegicus	RMDN3	RGD	RGD:1308697
Bos taurus	RMDN3	VGNC	VGNC:33993
Mus musculus	RMDN3	MGD	MGI:1915059
Canis familiaris	RMDN3	VGNC	VGNC:45607

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