SFXN5 - sideroflexin 5 Gene

Homo sapiens

Also known as BBG-TCC; SLC56A5

Gene ID: 94097 | Gene type: protein coding

About SFXN5

Cytogenetic location: 2p13.2 Genomic coordinates (GRCh38): 2:72,942,036-73,071,712 (from NCBI)

This gene has 22 transcripts (splice variants), 252 orthologues and 4 paralogues. Broad expression in brain (RPKM 13.0), liver (RPKM 3.8) and 20 other tissues.

Summary

Predicted to enable citrate transmembrane transporter activity. Predicted to be involved in citrate transport and mitochondrial transmembrane transport. Located in mitochondrion. [provided by Alliance of Genome Resources, Apr 2022]

SFXN5 Products(20)

mRNA	Protein	Name
NM_001330400.2	NP_001317329.1	sideroflexin-5 isoform 1
NM_001330401.2	NP_001317330.1	sideroflexin-5 isoform 3
NM_001330402.2	NP_001317331.1	sideroflexin-5 isoform 4
NM_001330403.2	NP_001317332.1	sideroflexin-5 isoform 5 precursor
NM_001330404.2	NP_001317333.1	sideroflexin-5 isoform 6
NM_001330405.2	NP_001317334.1	sideroflexin-5 isoform 7 precursor
NM_001330406.2	NP_001317335.1	sideroflexin-5 isoform 8 precursor
NM_001330407.2	NP_001317336.1	sideroflexin-5 isoform 9
NM_001330408.2	NP_001317337.1	sideroflexin-5 isoform 10
NM_001330410.2	NP_001317339.1	sideroflexin-5 isoform 6
NM_001330411.2	NP_001317340.1	sideroflexin-5 isoform 11
NM_001330412.2	NP_001317341.1	sideroflexin-5 isoform 11
NM_001371737.1	NP_001358666.1	sideroflexin-5 isoform 12
NM_001371738.1	NP_001358667.1	sideroflexin-5 isoform 13
NM_001371739.1	NP_001358668.1	sideroflexin-5 isoform 14
NM_001371740.1	NP_001358669.1	sideroflexin-5 isoform 15
NM_001371741.1	NP_001358670.1	sideroflexin-5 isoform 16
NM_001371742.1	NP_001358671.1	sideroflexin-5 isoform 17
NM_001371743.1	NP_001358672.1	sideroflexin-5 isoform 18
NM_144579.3	NP_653180.1	sideroflexin-5 isoform 2

SFXN5 Protein Structure

Mtc

0
100
200
300
340 a.a.

Protein Preferred Names

Protein Names

sideroflexin-5

Related Diseases

Diseases

Alias

Combined Oxidative Phosphorylation Deficiency 18

Growth And Developmental Delay-Hypotonia-Vision Impairment-Lactic Acidosis Syndrome	COXPD18
Combined Oxidative Phosphorylation Deficiency, Type 18

Parkinson Disease 21

PARK21	Parkinson'S Disease 21
Parkinson Disease, Type 21

Sengers Syndrome

Mitochondrial Dna Depletion Syndrome 10	Cardiomyopathy And Cataract
Cataract And Cardiomyopathy	MTDPS10
Congenital Cataract-Hypertrophic Cardiomyopathy-Mitochondrial Myopathy Syndrome	Cardiomyopathic Mitochondrial Dna Depletion Syndrome 10
Senger Syndrome

Parkinson Disease, Late-Onset

Parkinson Disease	Parkinson'S Disease
PD	PARK
Parkinson Disease, Susceptibility To	Late Onset Parkinson'S Disease
Late Onset Parkinson Disease	Paralysis Agitans
Primary Parkinsonism	Idiopathic Parkinson Disease
Parkinson'S	Parkinson Disease, Late-Onset, Susceptibility To
Parkinson Disease, Age Of Onset, Modifier	Lewy Body Parkinson Disease
Idiopathic Parkinson'S Disease	Pd - [Parkinson Disease]
Parkinson Disease Nos	Parkinson, Nos
Primary Parkinson Disease

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS12789	SFXN5 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	SFXN5	VGNC	VGNC:65073
Macaca mulatta	SFXN5	VGNC	VGNC:77243
Bos taurus	SFXN5	VGNC	VGNC:34534
Mus musculus	SFXN5	MGD	MGI:2137681
Rattus norvegicus	SFXN5	RGD	RGD:628706
Canis familiaris	SFXN5	VGNC	VGNC:46090

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