FAM210B - family with sequence similarity 210 member B Gene

Also Known as 5A3; C20orf108; dJ1167H4.1

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 116151

About FAM210B

Cytogenetic location: 20q13.2 Genomic coordinates (GRCh38): 20:56,358,974-56,368,663 (from NCBI)

This gene has 2 transcripts (splice variants), 205 orthologues and 1 paralogue. Ubiquitous expression in ovary (RPKM 51.5), adrenal (RPKM 50.1) and 25 other tissues.

Summary

Involved in cellular response to estradiol stimulus and positive regulation of erythrocyte differentiation. Located in mitochondrial outer membrane. Is intrinsic component of membrane. [provided by Alliance of Genome Resources, Apr 2022]

FAM210B Products (1)

mRNA Protein Name
NM_080821.3 NP_543011.2 protein FAM210B, mitochondrial

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
Biological Process GO Annotation Evidence References Source
involved in cellular response to estradiol stimulus IDA
IDA: Inferred from direct assay
26968549 GOA
involved in positive regulation of erythrocyte differentiation IMP
IMP: Inferred from mutant phenotype
26968549 GOA
Cellular Component GO Annotation Evidence References Source
located in membrane IDA
IDA: Inferred from direct assay
26968549 GOA
located in mitochondrial outer membrane IDA
IDA: Inferred from direct assay
26968549 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

FAM210B Protein Structure

DUF1279

DUF1279: Protein of unknown function (DUF1279) (87 - 174)

  • 0
  • 100
  • 192 a.a.
Protein Preferred Names Protein Names

protein FAM210B, mitochondrial

  • transmembrane protein C20orf108

FAM210B Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
FAM210B Q96KR6 NINJ2 Homo sapiens Q9NZG7
Validated Y2H
32296183
Intra
FAM210B Q96KR6 SERP1 Homo sapiens Q9Y6X1
Validated Y2H
32296183
Intra
FAM210B Q96KR6 RPRM Homo sapiens Q9NS64
Validated Y2H
32296183
Intra
FAM210B Q96KR6 MFF Homo sapiens Q9GZY8-5
Validated Y2H
32296183
Intra
FAM210B Q96KR6 LPAR3 Homo sapiens Q9UBY5
Validated Y2H
32296183
Intra
FAM210B Q96KR6 LNPEP Homo sapiens Q9UIQ6-2
Validated Y2H
32296183
Intra
FAM210B Q96KR6 HMOX1 Homo sapiens P09601
Y2H Prey Pooling
32296183
Intra
FAM210B Q96KR6 TMEM140 Homo sapiens Q9NV12
Validated Y2H
32296183
Intra
FAM210B Q96KR6 FIS1 Homo sapiens Q9Y3D6
Validated Y2H
32296183
Intra
FAM210B Q96KR6 ATP6V0B Homo sapiens Q99437
Validated Y2H
32296183
Intra
FAM210B Q96KR6 VKORC1 Homo sapiens Q9BQB6
Validated Y2H
32296183
Intra
FAM210B Q96KR6 TIMMDC1 Homo sapiens Q9NPL8
Validated Y2H
32296183
Intra
FAM210B Q96KR6 VAMP3 Homo sapiens Q15836
Y2H Prey Pooling
32296183
Intra
FAM210B Q96KR6 IER3IP1 Homo sapiens Q9Y5U9
Validated Y2H
32296183
Intra
FAM210B Q96KR6 BCL2L13 Homo sapiens Q9BXK5
Validated Y2H
32296183
Intra
FAM210B Q96KR6 SMCO4 Homo sapiens Q9NRQ5
Validated Y2H
32296183
Intra
FAM210B Q96KR6 CCDC167 Homo sapiens Q9P0B6
Validated Y2H
32296183
Intra
FAM210B Q96KR6 UBE2J1 Homo sapiens Q9Y385
Validated Y2H
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Ovarian Cancer

  • Ovarian Carcinoma

  • Ovarian Neoplasm

  • Malignant Tumour Of Ovary

  • Cancer Of The Ovary

  • Epithelial Ovarian Cancer

  • Neoplasm Of Ovary

  • Ovarian Neoplasms

  • Ovarian Cancers

  • Malignant Neoplasm Of Ovary

  • Primary Malignant Neoplasm Of Ovary

  • Ovarian Cancer, Somatic

  • Malignant Ovarian Tumor

  • Ovary Neoplasm

  • Primary Ovarian Cancer

  • Tumor Of The Ovary

  • Malignant Neoplasm Of The Ovary

  • Malignant Tumor Of The Ovary

  • Ovarian Malignant Tumor

  • OC

  • Ovarian Carcinomas

  • Cancer, Ovarian

  • Cancer Of Ovary

  • Ovary Cancer

  • Ca Ovary
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04708 FAM210B Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus FAM210B VGNC VGNC:28789
Macaca mulatta FAM210B VGNC VGNC:72275
Canis familiaris FAM210B VGNC VGNC:40658
Rattus norvegicus FAM210B RGD RGD:1311378
Mus musculus FAM210B MGD MGI:1914267
Others FAM210B NCBI