2. Gene
  3. AMIGO1 - adhesion molecule with Ig like domain 1 Gene

AMIGO1 - adhesion molecule with Ig like domain 1 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as ALI2; AMIGO; AMIGO-1

Gene ID: 57463 | Gene type: protein coding

About AMIGO1

Cytogenetic location: 1p13.3 Genomic coordinates (GRCh38): 1:109,504,178-109,509,727 (from NCBI)

This gene has 2 transcripts (splice variants), 248 orthologues and 2 paralogues. Ubiquitous expression in brain (RPKM 9.3), adrenal (RPKM 6.7) and 24 other tissues.

Summary

Predicted to enable Potassium Channel regulator activity. Predicted to be involved in several processes, including heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules; homophilic cell adhesion via plasma membrane adhesion molecules; and nervous system development. Predicted to act upstream of or within positive regulation of synapse assembly. Predicted to be located in dendrite and neuronal cell body membrane. Predicted to be integral component of membrane. Predicted to colocalize with voltage-gated Potassium Channel complex. [provided by Alliance of Genome Resources, Apr 2022]

AMIGO1 Products(1)

mRNA Protein Name
NM_020703.4 NP_065754.2 amphoterin-induced protein 1 precursor

AMIGO1 Protein Structure

LRR_8

LRR_8: Leucine rich repeat (110 - 170)

LRR_1

LRR_1: Leucine Rich Repeat (186 - 208)

V-set

V-set: Immunoglobulin V-set domain (285 - 357)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 493 a.a.
Protein Preferred Names Protein Names

amphoterin-induced protein 1

alivin-2

Related Diseases

Diseases Alias
Tungiasis

Tunga Penetrans Infestation

Chigger Flea

S Penetrans

Sarcopsylla Penetrans

T Penetrans

Tunga Penetrans

Sand-Flea Infestation

Jiggers Infestation

Chigoe Infestation

Jigger Disease
Developmental And Epileptic Encephalopathy 26

DEE26

Epileptic Encephalopathy, Early Infantile, 26

Eiee26

Early Infantile Epileptic Encephalopathy 26

Developmental And Epileptic Encephalopathy, 26

Encephalopathy, Epileptic, Early Infantile, Type 26
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS00657 AMIGO1 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus AMIGO1 MGD MGI:2653612
Felis catus AMIGO1 VGNC VGNC:59765
Rattus norvegicus AMIGO1 RGD RGD:1303079
Bos taurus AMIGO1 VGNC VGNC:25865
Canis familiaris AMIGO1 VGNC VGNC:37831
Macaca mulatta AMIGO1 VGNC VGNC:69653