CSGALNACT2 - chondroitin sulfate N-acetylgalactosaminyltransferase 2 Gene

Also Known as CHGN2; ChGn-2; PRO0082; GALNACT2; GALNACT-2; beta4GalNAcT

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 55454

Summary

This gene encodes a member of the chondroitin N-acetylgalactosaminyltransferase family. The encoded protein is involved in elongation during chondroitin sulfate synthesis. Alternative splicing of this gene results in multiple transcript variants. Two related pseudogenes have been identified on chromosome X. [provided by RefSeq, Feb 2016]
Broad expression in bone marrow (RPKM 48.3), gall bladder (RPKM 16.8) and 23 other tissues.

CSGALNACT2 Products (3)

mRNA Protein Name
NM_001319654.1 NP_001306583.1 chondroitin sulfate N-acetylgalactosaminyltransferase 2 isoform 2
NM_001319656.1 NP_001306585.1 chondroitin sulfate N-acetylgalactosaminyltransferase 2 isoform 3
NM_018590.5 NP_061060.3 chondroitin sulfate N-acetylgalactosaminyltransferase 2 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Verweise Source
enables acetylgalactosaminyltransferase activity IDA
IDA: Inferred from direct assay
11788602 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
25416956 GOA
Biological Process GO Annotation Evidence Verweise Source
involved in chondroitin sulfate proteoglycan biosynthetic process IDA
IDA: Inferred from direct assay
11788602 GOA
involved in dermatan sulfate proteoglycan biosynthetic process IDA
IDA: Inferred from direct assay
11788602 GOA
involved in proteoglycan biosynthetic process IDA
IDA: Inferred from direct assay
11788602 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

CSGALNACT2 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Verweise
Intra
CSGALNACT2 Q8N6G5 UBE2I Homo sapiens Q7KZS0
Y2H Array
32296183
Intra
CSGALNACT2 Q8N6G5 UBE2I Homo sapiens Q7KZS0
Y2H Prey Pooling
32296183
Intra
CSGALNACT2 Q8N6G5 RETREG3 Homo sapiens Q86VR2
Y2H Prey Pooling
32296183
Intra
CSGALNACT2 Q8N6G5 RETREG3 Homo sapiens Q86VR2
Y2H Array
32296183
Intra
CSGALNACT2 Q8N6G5 CYB5R3 Homo sapiens P00387
Y2H Prey Pooling
32296183
Intra
CSGALNACT2 Q8N6G5 CYB5R3 Homo sapiens P00387
Y2H Array
32296183
Intra
CSGALNACT2 Q8N6G5 HSD17B11 Homo sapiens Q8NBQ5
Y2H Array
32296183
Intra
CSGALNACT2 Q8N6G5 HSD17B11 Homo sapiens Q8NBQ5
Y2H Prey Pooling
32296183
Intra
CSGALNACT2 Q8N6G5 HSD17B11 Homo sapiens Q8NBQ5
Validated Y2H
32296183
Intra
CSGALNACT2 Q8N6G5 ARL13B Homo sapiens Q3SXY8
Y2H Array
32296183
Intra
CSGALNACT2 Q8N6G5 ARL13B Homo sapiens Q3SXY8
Y2H Prey Pooling
32296183
Intra
CSGALNACT2 Q8N6G5 ATP1B4 Homo sapiens Q9UN42
Y2H Prey Pooling
32296183
Intra
CSGALNACT2 Q8N6G5 ATP1B4 Homo sapiens Q9UN42
Validated Y2H
32296183
Intra
CSGALNACT2 Q8N6G5 ATP1B4 Homo sapiens Q9UN42
Y2H Array
32296183
Intra
CSGALNACT2 Q8N6G5 TMEM143 Homo sapiens Q96AN5
Y2H Prey Pooling
32296183
Intra
CSGALNACT2 Q8N6G5 TMEM143 Homo sapiens Q96AN5
Validated Y2H
32296183
Intra
CSGALNACT2 Q8N6G5 TMEM143 Homo sapiens Q96AN5
Y2H Array
32296183
Intra
CSGALNACT2 Q8N6G5 GPR152 Homo sapiens Q8TDT2
Validated Y2H
32296183
Intra
CSGALNACT2 Q8N6G5 GPR152 Homo sapiens Q8TDT2
Y2H Prey Pooling
32296183
Intra
CSGALNACT2 Q8N6G5 GPR152 Homo sapiens Q8TDT2
Y2H Array
32296183
Intra
CSGALNACT2 Q8N6G5 SLC35E3 Homo sapiens Q7Z769
Y2H Prey Pooling
32296183
Intra
CSGALNACT2 Q8N6G5 SLC35E3 Homo sapiens Q7Z769
Y2H Array
32296183
Intra
CSGALNACT2 Q8N6G5 FCGR2A Homo sapiens P12318-2
Y2H Array
32296183
Intra
CSGALNACT2 Q8N6G5 FCGR2A Homo sapiens P12318-2
Y2H Prey Pooling
32296183
Intra
CSGALNACT2 Q8N6G5 MUC1 Homo sapiens P15941-11
Y2H Prey Pooling
32296183
Intra
CSGALNACT2 Q8N6G5 MUC1 Homo sapiens P15941-11
Y2H Array
32296183
Intra
CSGALNACT2 Q8N6G5 SSMEM1 Homo sapiens Q8WWF3
Y2H Prey Pooling
32296183
Intra
CSGALNACT2 Q8N6G5 SSMEM1 Homo sapiens Q8WWF3
Y2H Array
32296183
Intra
CSGALNACT2 Q8N6G5 SSMEM1 Homo sapiens Q8WWF3
Validated Y2H
32296183
Intra
CSGALNACT2 Q8N6G5 TMEM52B Homo sapiens Q4KMG9
Y2H Array
32296183
Intra
CSGALNACT2 Q8N6G5 TMEM52B Homo sapiens Q4KMG9
Y2H Prey Pooling
32296183
Intra
CSGALNACT2 Q8N6G5 MFSD14B Homo sapiens Q5SR56
Y2H Prey Pooling
32296183
Intra
CSGALNACT2 Q8N6G5 MFSD14B Homo sapiens Q5SR56
Y2H Array
32296183
Intra
CSGALNACT2 Q8N6G5 SYT1 Homo sapiens P21579
Y2H Prey Pooling
32296183
Intra
CSGALNACT2 Q8N6G5 SYT1 Homo sapiens P21579
Y2H Array
32296183
Intra
CSGALNACT2 Q8N6G5 CREB3L1 Homo sapiens Q96BA8
Y2H Prey Pooling
32296183
Intra
CSGALNACT2 Q8N6G5 CREB3L1 Homo sapiens Q96BA8
Validated Y2H
32296183
Intra
CSGALNACT2 Q8N6G5 CREB3L1 Homo sapiens Q96BA8
Y2H Array
32296183
Intra
CSGALNACT2 Q8N6G5 CLDN2 Homo sapiens P57739
Y2H Prey Pooling
32296183
Intra
CSGALNACT2 Q8N6G5 CLDN2 Homo sapiens P57739
Y2H Array
32296183
Intra
CSGALNACT2 Q8N6G5 BSND Homo sapiens Q8WZ55
Validated Y2H
32296183
Intra
CSGALNACT2 Q8N6G5 BSND Homo sapiens Q8WZ55
Y2H Array
32296183
Intra
CSGALNACT2 Q8N6G5 BSND Homo sapiens Q8WZ55
Y2H Prey Pooling
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-P5045 Fmoc-Thr(GalNAc(Ac)3-β-D)-OH / Unkown