TMEM143 - transmembrane protein 143 Gene

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 55260

Summary

Predicted to act upstream of or within hematopoietic progenitor cell differentiation. Located in mitochondrion. [provided by Alliance of Genome Resources, Jul 2025]
Ubiquitous expression in heart (RPKM 9.0), fat (RPKM 4.7) and 25 other tissues.

TMEM143 Products (4)

mRNA Protein Name
NM_001303538.2 NP_001290467.1 transmembrane protein 143 isoform b
NM_001303539.2 NP_001290468.1 transmembrane protein 143 isoform c
NM_001303540.2 NP_001290469.1 transmembrane protein 143 isoform d
NM_018273.4 NP_060743.2 transmembrane protein 143 isoform a

TMEM143 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
TMEM143 Q96AN5 LSMEM2 Homo sapiens Q8N112
Y2H Array
32296183
Intra
TMEM143 Q96AN5 LSMEM2 Homo sapiens Q8N112
Y2H Prey Pooling
32296183
Intra
TMEM143 Q96AN5 ORMDL1 Homo sapiens Q9P0S3
Validated Y2H
32296183
Intra
TMEM143 Q96AN5 AQP6 Homo sapiens Q13520
Y2H Array
32296183
Intra
TMEM143 Q96AN5 AQP6 Homo sapiens Q13520
Y2H Prey Pooling
32296183
Intra
TMEM143 Q96AN5 REEP6 Homo sapiens Q96HR9-2
Validated Y2H
32296183
Intra
TMEM143 Q96AN5 SLC10A6 Homo sapiens Q3KNW5
Y2H Array
32296183
Intra
TMEM143 Q96AN5 SLC10A6 Homo sapiens Q3KNW5
Y2H Prey Pooling
32296183
Intra
TMEM143 Q96AN5 LIME1 Homo sapiens Q9H400
Validated Y2H
32296183
Intra
TMEM143 Q96AN5 LIME1 Homo sapiens Q9H400
Y2H Array
32296183
Intra
TMEM143 Q96AN5 LIME1 Homo sapiens Q9H400
Y2H Prey Pooling
32296183
Intra
TMEM143 Q96AN5 NAT8 Homo sapiens Q9UHE5
Validated Y2H
32296183
Intra
TMEM143 Q96AN5 ABHD16A Homo sapiens O95870
Y2H Array
32296183
Intra
TMEM143 Q96AN5 ABHD16A Homo sapiens O95870
Y2H Prey Pooling
32296183
Intra
TMEM143 Q96AN5 YIPF2 Homo sapiens Q9BWQ6
Validated Y2H
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (7)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14657 TMEM123 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS14668 TMEM140 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS14669 TMEM145 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS14670 TMEM147 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS14671 TMEM14C Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS14677 TMEM163 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS14724 TMEM43 Human Pre-designed siRNA Set A Pre-designed Set / Unkown