SAR1A - secretion associated Ras related GTPase 1A Gene

Homo sapiens

Also known as SAR1; Sara; SARA1; masra2

Gene ID: 56681 | Gene type: protein coding

About SAR1A

Cytogenetic location: 10q22.1 Genomic coordinates (GRCh38): 10:70,147,289-70,170,514 (from NCBI)

This gene has 8 transcripts (splice variants), 121 orthologues and 30 paralogues. Ubiquitous expression in fat (RPKM 47.2), placenta (RPKM 41.9) and 25 other tissues.

Summary

Predicted to enable GTPase activity. Involved in COPII-coated vesicle cargo loading. Part of COPII vesicle coat. [provided by Alliance of Genome Resources, Apr 2022]

SAR1A Products(2)

mRNA	Protein	Name
NM_001142648.2	NP_001136120.1	GTP-binding protein SAR1a
NM_020150.5	NP_064535.1	GTP-binding protein SAR1a

SAR1A Protein Structure

Arf

0
100
198 a.a.

Protein Preferred Names

Protein Names

GTP-binding protein SAR1a

COPII-associated small GTPase

Recombinant SAR1A Proteins

Cat. No.	Product Name	Accession	Purity
HY-P71634	SAR1A Protein, Human (GST)	Q9NR31 (1M-198D)	≥95%

Related Diseases

Diseases

Alias

Spondyloepiphyseal Dysplasia Tarda, X-Linked

Spondyloepiphyseal Dysplasia Tarda	X-Linked Spondyloepiphyseal Dysplasia Tarda
SEDT	Sed Tarda, X-Linked
Spondyloepiphyseal Dysplasia, Late	Spondyloepiphyseal Dysplasia Tarda X-Linked
Sed	X Linked Spondyloepiphyseal Dysplasia Tarda
X-Linked Spondyloepiphyseal Dysplasia	Late Onset Spondyloepiphyseal Dysplasia
Sed Tarda	X-Linked Sed
X-Linked Sedt	Dysplasia, Spondyloepiphyseal, Tarda
Spondyloepiphyseal Dysplasia

Chylomicron Retention Disease

CMRD	Anderson Disease
Lipid Transport Defect Of Intestine	Hypobetalipoproteinemia With Accumulation Of Apolipoprotein B-Like Protein In Intestinal Cells
Andd	Anderson Syndrome
Crd	Andersons Disease
Malabsorption Syndrome

Craniolenticulosutural Dysplasia

Boyadjiev-Jabs Syndrome	CLSD
Cranio-Lenticulo-Sutural Dysplasia	Cranio-Lenticulo-Sutural Dysplasia, Clsd

Oculomotor Nerve Paralysis

Iii Nerve Palsy	Iiird Nerve Paralysis
Third Cranial Nerve Paralysis

Intracranial Hypotension

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS12442	SAR1A Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	SAR1A	VGNC	VGNC:76969
Bos taurus	SAR1A	VGNC	VGNC:34286
Rattus norvegicus	SAR1A	RGD	RGD:1359540
Mus musculus	SAR1A	MGD	MGI:98230
Others	SAR1A	NCBI

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