TMEM19 - transmembrane protein 19 Gene

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 55266

About TMEM19

This gene has 6 transcripts (splice variants) and 201 orthologues. Ubiquitous expression in kidney (RPKM 11.7), duodenum (RPKM 10.9) and 25 other tissues.

Summary

Predicted to be integral component of membrane. Predicted to be active in membrane. [provided by Alliance of Genome Resources, Apr 2022]

TMEM19 Products (1)

mRNA Protein Name
NM_018279.4 NP_060749.2 transmembrane protein 19

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
16189514 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

TMEM19 Protein Structure

DUF92

DUF92: Integral membrane protein DUF92 (58 - 322)

  • 0
  • 100
  • 200
  • 300
  • 336 a.a.
Protein Preferred Names Protein Names

transmembrane protein 19

TMEM19 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
TMEM19 Q96HH6 BSCL2 Homo sapiens Q96G97-4
Y2H Array
31515488
Intra
TMEM19 Q96HH6 BSCL2 Homo sapiens Q96G97-4
Y2H Prey Pooling
25416956
Intra
TMEM19 Q96HH6 BSCL2 Homo sapiens Q96G97-4
Y2H Array
25416956
Intra
TMEM19 Q96HH6 PGRMC2 Homo sapiens O15173
Y2H Prey Pooling
32296183
Intra
TMEM19 Q96HH6 PGRMC2 Homo sapiens O15173
Y2H Array
32296183
Intra
TMEM19 Q96HH6 TMEM45A Homo sapiens Q9NWC5
Y2H Array
32296183
Intra
TMEM19 Q96HH6 TMEM45A Homo sapiens Q9NWC5
Y2H Prey Pooling
32296183
Intra
TMEM19 Q96HH6 TMEM45A Homo sapiens Q9NWC5
Validated Y2H
32296183
Intra
TMEM19 Q96HH6 PTGES Homo sapiens O14684
Y2H Prey Pooling
32296183
Intra
TMEM19 Q96HH6 PTGES Homo sapiens O14684
Y2H Array
32296183
Intra
TMEM19 Q96HH6 BSCL2 Homo sapiens J3KQ12
Y2H Array
32296183
Intra
TMEM19 Q96HH6 BSCL2 Homo sapiens J3KQ12
Y2H Prey Pooling
32296183
Intra
TMEM19 Q96HH6 GPX8 Homo sapiens Q8TED1
Y2H Prey Pooling
32296183
Intra
TMEM19 Q96HH6 GPX8 Homo sapiens Q8TED1
Y2H Array
32296183
Intra
TMEM19 Q96HH6 TLCD4 Homo sapiens Q96MV1
Y2H Array
32296183
Intra
TMEM19 Q96HH6 TLCD4 Homo sapiens Q96MV1
Y2H Prey Pooling
32296183
Intra
TMEM19 Q96HH6 TLCD4 Homo sapiens Q96MV1
Validated Y2H
32296183
Intra
TMEM19 Q96HH6 AQP6 Homo sapiens Q13520
Y2H Prey Pooling
32296183
Intra
TMEM19 Q96HH6 AQP6 Homo sapiens Q13520
Y2H Array
32296183
Intra
TMEM19 Q96HH6 GPRC5D Homo sapiens Q9NZD1
Y2H Prey Pooling
32296183
Intra
TMEM19 Q96HH6 GPRC5D Homo sapiens Q9NZD1
Validated Y2H
32296183
Intra
TMEM19 Q96HH6 GPRC5D Homo sapiens Q9NZD1
Y2H Array
32296183
Intra
TMEM19 Q96HH6 C10orf67 Homo sapiens Q8IYJ2-2
Y2H Prey Pooling
32296183
Intra
TMEM19 Q96HH6 C10orf67 Homo sapiens Q8IYJ2-2
Y2H Array
32296183
Intra
TMEM19 Q96HH6 SERTM1 Homo sapiens A2A2V5
Y2H Array
32296183
Intra
TMEM19 Q96HH6 SERTM1 Homo sapiens A2A2V5
Y2H Prey Pooling
32296183
Intra
TMEM19 Q96HH6 GJB1 Homo sapiens P08034
Y2H Prey Pooling
32296183
Intra
TMEM19 Q96HH6 GJB1 Homo sapiens P08034
Y2H Array
32296183
Intra
TMEM19 Q96HH6 PIGP Homo sapiens P57054
Y2H Array
32296183
Intra
TMEM19 Q96HH6 PIGP Homo sapiens P57054
Y2H Prey Pooling
32296183
Intra
TMEM19 Q96HH6 CPLX4 Homo sapiens Q7Z7G2
Y2H Array
32296183
Intra
TMEM19 Q96HH6 CPLX4 Homo sapiens Q7Z7G2
Y2H Prey Pooling
32296183
Intra
TMEM19 Q96HH6 HSD17B13 Homo sapiens Q7Z5P4
Y2H Array
32296183
Intra
TMEM19 Q96HH6 HSD17B13 Homo sapiens Q7Z5P4
Y2H Prey Pooling
32296183
Intra
TMEM19 Q96HH6 GPR42 Homo sapiens O15529
Y2H Prey Pooling
32296183
Intra
TMEM19 Q96HH6 GPR42 Homo sapiens O15529
Y2H Array
32296183
Intra
TMEM19 Q96HH6 LY6E Homo sapiens Q16553
Y2H Array
32296183
Intra
TMEM19 Q96HH6 LY6E Homo sapiens Q16553
Y2H Prey Pooling
32296183
Intra
TMEM19 Q96HH6 ELOVL4 Homo sapiens Q9GZR5
Y2H Array
32296183
Intra
TMEM19 Q96HH6 ELOVL4 Homo sapiens Q9GZR5
Y2H Prey Pooling
32296183
Intra
TMEM19 Q96HH6 ELOVL4 Homo sapiens Q9GZR5
Validated Y2H
32296183
Intra
TMEM19 Q96HH6 FAM210B Homo sapiens Q96KR6
Y2H Prey Pooling
32296183
Intra
TMEM19 Q96HH6 FAM210B Homo sapiens Q96KR6
Validated Y2H
32296183
Intra
TMEM19 Q96HH6 FAM210B Homo sapiens Q96KR6
Y2H Array
32296183
Intra
TMEM19 Q96HH6 TEX29 Homo sapiens Q8N6K0
Y2H Prey Pooling
32296183
Intra
TMEM19 Q96HH6 TEX29 Homo sapiens Q8N6K0
Y2H Array
32296183
Intra
TMEM19 Q96HH6 RNF185 Homo sapiens Q96GF1
Y2H Array
32296183
Intra
TMEM19 Q96HH6 RNF185 Homo sapiens Q96GF1
Y2H Prey Pooling
32296183
Intra
TMEM19 Q96HH6 CNR2 Homo sapiens P34972
Y2H Prey Pooling
32296183
Intra
TMEM19 Q96HH6 CNR2 Homo sapiens P34972
Y2H Array
32296183
Intra
TMEM19 Q96HH6 SUSD6 Homo sapiens Q92537
Y2H Array
32296183
Intra
TMEM19 Q96HH6 SUSD6 Homo sapiens Q92537
Y2H Prey Pooling
32296183
Intra
TMEM19 Q96HH6 MFSD14B Homo sapiens Q5SR56
Y2H Array
32296183
Intra
TMEM19 Q96HH6 MFSD14B Homo sapiens Q5SR56
Y2H Prey Pooling
32296183
Intra
TMEM19 Q96HH6 GORAB Homo sapiens Q5T7V8
Y2H Prey Pooling
32296183
Intra
TMEM19 Q96HH6 GORAB Homo sapiens Q5T7V8
Y2H Array
32296183
Intra
TMEM19 Q96HH6 APOA5 Homo sapiens Q6Q788
Y2H Array
32296183
Intra
TMEM19 Q96HH6 APOA5 Homo sapiens Q6Q788
Y2H Prey Pooling
32296183
Intra
TMEM19 Q96HH6 SLC7A1 Homo sapiens P30825
Y2H Array
32296183
Intra
TMEM19 Q96HH6 SLC7A1 Homo sapiens P30825
Y2H Prey Pooling
32296183
Intra
TMEM19 Q96HH6 CREB3L1 Homo sapiens Q96BA8
Y2H Prey Pooling
32296183
Intra
TMEM19 Q96HH6 CREB3L1 Homo sapiens Q96BA8
Y2H Array
32296183
Intra
TMEM19 Q96HH6 LDAF1 Homo sapiens Q96B96
Y2H Prey Pooling
32296183
Intra
TMEM19 Q96HH6 LDAF1 Homo sapiens Q96B96
Y2H Array
32296183
Intra
TMEM19 Q96HH6 TMEM139 Homo sapiens Q8IV31
Y2H Array
32296183
Intra
TMEM19 Q96HH6 TMEM139 Homo sapiens Q8IV31
Y2H Prey Pooling
32296183
Intra
TMEM19 Q96HH6 BSCL2 Homo sapiens Q96G97
Y2H Prey Pooling
25416956
Intra
TMEM19 Q96HH6 KASH5 Homo sapiens Q8N6L0
Y2H Array
32296183
Intra
TMEM19 Q96HH6 KASH5 Homo sapiens Q8N6L0
Y2H Prey Pooling
32296183
Intra
TMEM19 Q96HH6 LEPROTL1 Homo sapiens O95214
Y2H Array
32296183
Intra
TMEM19 Q96HH6 LEPROTL1 Homo sapiens O95214
Y2H Prey Pooling
32296183
Intra
TMEM19 Q96HH6 REEP4 Homo sapiens Q9H6H4
Validated Y2H
32296183
Intra
TMEM19 Q96HH6 REEP4 Homo sapiens Q9H6H4
Y2H Prey Pooling
32296183
Intra
TMEM19 Q96HH6 REEP4 Homo sapiens Q9H6H4
Y2H Array
32296183
Intra
TMEM19 Q96HH6 CD79A Homo sapiens P11912
Y2H Array
32296183
Intra
TMEM19 Q96HH6 CD79A Homo sapiens P11912
Y2H Prey Pooling
32296183
Intra
TMEM19 Q96HH6 TMEM14B Homo sapiens Q9NUH8
Y2H Array
32296183
Intra
TMEM19 Q96HH6 TMEM14B Homo sapiens Q9NUH8
Validated Y2H
32296183
Intra
TMEM19 Q96HH6 TMEM14B Homo sapiens Q9NUH8
Y2H Prey Pooling
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-W009123 Erucamide Inhibitor 99.32% Unkown
HY-RS14691 TMEM19 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29458 Tmem19 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29459 Tmem19 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta TMEM19 VGNC VGNC:82259
Rattus norvegicus TMEM19 RGD RGD:735209
Mus musculus TMEM19 MGD MGI:1914476
Canis familiaris TMEM19 VGNC VGNC:47514
Bos taurus TMEM19 VGNC VGNC:36015
Felis catus TMEM19 VGNC VGNC:66301
Others TMEM19 NCBI