LDAF1 - lipid droplet assembly factor 1 Gene
Also Known as TMEM159
Species: Homo sapiens
Gene Type: protein coding
Gene ID: 57146
Summary
Involved in lipid droplet formation. Located in endoplasmic reticulum membrane and lipid droplet. [provided by Alliance of Genome Resources, Jul 2025]
Ubiquitous expression in heart (RPKM 19.6), skin (RPKM 18.8) and 23 other tissues.
LDAF1 Products (6)
| mRNA | Protein | Name |
|---|---|---|
| NM_001301769.2 | NP_001288698.1 | lipid droplet assembly factor 1 isoform 2 |
| NM_001301771.2 | NP_001288700.1 | lipid droplet assembly factor 1 isoform 2 |
| NM_001301773.2 | NP_001288702.1 | lipid droplet assembly factor 1 isoform 3 |
| NM_001301774.2 | NP_001288703.1 | lipid droplet assembly factor 1 isoform 3 |
| NM_001301775.2 | NP_001288704.1 | lipid droplet assembly factor 1 isoform 1 |
| NM_020422.6 | NP_065155.3 | lipid droplet assembly factor 1 isoform 2 |
| Molecular Function GO Annotation | Evidence | References | Source |
|---|---|---|---|
| enables protein binding |
IPI
IPI: Inferred from physical interaction
|
21516116 | GOA |
| Biological Process GO Annotation | Evidence | References | Source |
|---|---|---|---|
| involved in lipid droplet formation |
IMP
IMP: Inferred from mutant phenotype
|
31708432 | GOA |
| Cellular Component GO Annotation | Evidence | References | Source |
|---|---|---|---|
| located in endoplasmic reticulum membrane |
IDA
IDA: Inferred from direct assay
|
30901948 | GOA |
| located in lipid droplet |
IDA
IDA: Inferred from direct assay
|
30901948 | GOA |
EXP: Inferred from Experiment
IDA: Inferred from direct assay
IPI: Inferred from physical interaction
IMP: Inferred from mutant phenotype
IGI: Inferred from genetic interaction
IEP: Inferred from expression pattern
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LDAF1 Protein-protein interaction Information
|
Type
|
Protein Name | Protein ID | Interactor | Interactor Species | Interactor ID | Detection Method | References |
|---|---|---|---|---|---|---|---|
|
Intra
|
LDAF1 | Q96B96 | TMEM19 | Homo sapiens | Q96HH6 | 32296183 | |
|
Intra
|
LDAF1 | Q96B96 | COQ8A | Homo sapiens | Q8NI60 | 25416956 | |
|
Intra
|
LDAF1 | Q96B96 | COQ8A | Homo sapiens | Q8NI60 | 25416956 | |
|
Intra
|
LDAF1 | Q96B96 | COQ8A | Homo sapiens | Q8NI60 | 25416956 | |
|
Intra
|
LDAF1 | Q96B96 | CACFD1 | Homo sapiens | Q9UGQ2 | 25416956 | |
|
Intra
|
LDAF1 | Q96B96 | CACFD1 | Homo sapiens | Q9UGQ2 | 25416956 | |
|
Intra
|
LDAF1 | Q96B96 | CACFD1 | Homo sapiens | Q9UGQ2 | 21516116 | |
|
Intra
|
LDAF1 | Q96B96 | SEC22A | Homo sapiens | Q96IW7 | 32296183 |
Cross: Cross-species interaction
Intra: Intraspecies interaction