TMEM45A - transmembrane protein 45A Gene

Homo sapiens

Also known as DERP7; DNAPTP4

Gene ID: 55076 | Gene type: protein coding

About TMEM45A

Cytogenetic location: 3q12.2 Genomic coordinates (GRCh38): 3:100,492,619-100,577,444 (from NCBI)

This gene has 7 transcripts (splice variants), 221 orthologues and 2 paralogues. Biased expression in skin (RPKM 215.6), liver (RPKM 25.9) and 2 other tissues.

Summary

Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]

TMEM45A Products(2)

mRNA	Protein	Name
NM_001363876.2	NP_001350805.1	transmembrane protein 45A isoform 1
NM_018004.3	NP_060474.1	transmembrane protein 45A isoform 2

TMEM45A Protein Structure

DUF716

0
100
200
275 a.a.

Protein Preferred Names

Protein Names

transmembrane protein 45A

DNA polymerase-transactivated protein 4

Related Diseases

Diseases

Alias

Pollen Allergy

Hay Fever

Fanconi Anemia, Complementation Group A

Fanconi Anemia	Fanconi Pancytopenia
Fanconi Anemia Complementation Group A	FANCA
Fa	Fanconi Panmyelopathy
Fanconi'S Anemia	Fanconi Anaemia
Fanconi'S Anaemia	Fanconi Hypoplastic Anemia
Estren-Dameshek Variant Of Fanconi Anemia	Estren-Dameshek Variant Of Fanconi Pancytopenia
Fanconi Anemia Estren-Dameshek Variant	Fanconis Anemia

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS14726	TMEM45A Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	TMEM45A	MGD	MGI:1913122
Canis familiaris	TMEM45A	VGNC	VGNC:47582
Felis catus	TMEM45A	VGNC	VGNC:66348
Rattus norvegicus	TMEM45A	RGD	RGD:6495353
Macaca mulatta	TMEM45A	VGNC	VGNC:79499

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