Ephrin-A5
Ephrin-A5, the product of EFNA5, is a GPI-linked ligand for EphA receptors and one of the best-characterized guidance cues in the nervous system. Together with ephrin-A2 and ephrin-A3 it establishes the gradient that maps retinal ganglion cell axons onto the optic tectum and superior colliculus, and it further shapes corticofugal and commissural axon trajectories. Beyond development, ephrin-A5 interacts with EphA5 on pancreatic beta cells to restrain glucose-stimulated insulin secretion, connecting an axon-guidance molecule to metabolic control. It also modulates axon regeneration after injury, generally acting as an inhibitor of neurite outgrowth. Recombinant ephrin-A5 is widely used to probe EphA receptor activation and repulsive signaling.
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Ephrin-A5 Recombinant Proteins (9)
Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
- Formula: Human
- Molecular Weight: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
