TMEM182 - transmembrane protein 182 Gene

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 130827

About TMEM182

This gene has 11 transcripts (splice variants) and 253 orthologues. Biased expression in heart (RPKM 27.0), prostate (RPKM 2.7) and 2 other tissues.

Summary

Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]

TMEM182 Products (5)

mRNA Protein Name
NM_001321343.2 NP_001308272.2 transmembrane protein 182 isoform b
NM_001321344.2 NP_001308273.2 transmembrane protein 182 isoform b
NM_001321345.2 NP_001308274.2 transmembrane protein 182 isoform c
NM_001321346.2 NP_001308275.2 transmembrane protein 182 isoform d
NM_144632.5 NP_653233.5 transmembrane protein 182 isoform a precursor

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
25416956 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

TMEM182 Protein Structure

Claudin_2

Claudin_2: PMP-22/EMP/MP20/Claudin tight junction (16 - 220)

  • 0
  • 100
  • 200
  • 229 a.a.
Protein Preferred Names Protein Names

transmembrane protein 182

TMEM182 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
TMEM182 Q6ZP80 LGALS3 Homo sapiens P17931
Anti Tag CoIP
33961781
Intra
TMEM182 Q6ZP80 LGALS3 Homo sapiens P17931
Anti Tag CoIP
28514442
Intra
TMEM182 Q6ZP80 FNDC9 Homo sapiens Q8TBE3
Validated Y2H
32296183
Intra
TMEM182 Q6ZP80 FNDC9 Homo sapiens Q8TBE3
Y2H Array
32296183
Intra
TMEM182 Q6ZP80 FNDC9 Homo sapiens Q8TBE3
Y2H Prey Pooling
32296183
Intra
TMEM182 Q6ZP80 PLP1 Homo sapiens P60201-2
Y2H Prey Pooling
32296183
Intra
TMEM182 Q6ZP80 PLP1 Homo sapiens P60201-2
Y2H Array
32296183
Intra
TMEM182 Q6ZP80 MS4A3 Homo sapiens Q96HJ5
Validated Y2H
32296183
Intra
TMEM182 Q6ZP80 MS4A3 Homo sapiens Q96HJ5
Y2H Array
32296183
Intra
TMEM182 Q6ZP80 MS4A3 Homo sapiens Q96HJ5
Y2H Prey Pooling
32296183
Intra
TMEM182 Q6ZP80 GJA8 Homo sapiens P48165
Y2H Prey Pooling
32296183
Intra
TMEM182 Q6ZP80 GJA8 Homo sapiens P48165
Y2H Array
32296183
Intra
TMEM182 Q6ZP80 GPR42 Homo sapiens O15529
Y2H Array
32296183
Intra
TMEM182 Q6ZP80 GPR42 Homo sapiens O15529
Y2H Prey Pooling
32296183
Intra
TMEM182 Q6ZP80 SUSD3 Homo sapiens Q96L08
Validated Y2H
32296183
Intra
TMEM182 Q6ZP80 SUSD3 Homo sapiens Q96L08
Y2H Prey Pooling
32296183
Intra
TMEM182 Q6ZP80 SUSD3 Homo sapiens Q96L08
Y2H Array
32296183
Intra
TMEM182 Q6ZP80 CLDN5 Homo sapiens O00501
Y2H Array
32296183
Intra
TMEM182 Q6ZP80 CLDN5 Homo sapiens O00501
Y2H Prey Pooling
32296183
Intra
TMEM182 Q6ZP80 TSPAN12 Homo sapiens O95859
Y2H Array
32296183
Intra
TMEM182 Q6ZP80 TSPAN12 Homo sapiens O95859
Y2H Prey Pooling
32296183
Intra
TMEM182 Q6ZP80 TMEM140 Homo sapiens Q9NV12
Validated Y2H
32296183
Intra
TMEM182 Q6ZP80 SYNE4 Homo sapiens Q8N205
Validated Y2H
25416956
Intra
TMEM182 Q6ZP80 SMIM3 Homo sapiens Q9BZL3
Y2H Prey Pooling
32296183
Intra
TMEM182 Q6ZP80 SMIM3 Homo sapiens Q9BZL3
Validated Y2H
32296183
Intra
TMEM182 Q6ZP80 SMIM3 Homo sapiens Q9BZL3
Y2H Array
32296183
Intra
TMEM182 Q6ZP80 KLRC1 Homo sapiens P26715
Y2H Array
32296183
Intra
TMEM182 Q6ZP80 KLRC1 Homo sapiens P26715
Y2H Prey Pooling
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14689 TMEM182 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus TMEM182 VGNC VGNC:36008
Canis familiaris TMEM182 VGNC VGNC:47507
Macaca mulatta TMEM182 VGNC VGNC:79604
Mus musculus TMEM182 MGD MGI:1923725
Rattus norvegicus TMEM182 RGD RGD:1563696
Felis catus TMEM182 VGNC VGNC:66297
Others TMEM182 NCBI