SUSD3 - sushi domain containing 3 Gene

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 203328

About SUSD3

Cytogenetic location: 9q22.31 Genomic coordinates (GRCh38): 9:93,058,701-93,085,133 (from NCBI)

This gene has 5 transcripts (splice variants), 121 orthologues and 39 paralogues. Biased expression in testis (RPKM 12.2), lymph node (RPKM 7.6) and 12 other tissues.

Summary

Located in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

SUSD3 Products (5)

mRNA	Protein	Name
NM_001287005.2	NP_001273934.1	sushi domain-containing protein 3 isoform b
NM_001287006.2	NP_001273935.1	sushi domain-containing protein 3 isoform c
NM_001287007.2	NP_001273936.1	sushi domain-containing protein 3 isoform d
NM_001287008.2	NP_001273937.1	sushi domain-containing protein 3 isoform e
NM_145006.4	NP_659443.1	sushi domain-containing protein 3 isoform a

Gene Ontology

Molecular Function
Cellular Component

Molecular Function GO Annotation	Evidence	References	Source
enables protein binding	IPI IPI: Inferred from physical interaction	32296183	GOA

Cellular Component GO Annotation	Evidence	References	Source
located in plasma membrane	IDA IDA: Inferred from direct assay	24413080	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

SUSD3 Protein Structure

Sushi

0
100
200
255 a.a.

Protein Preferred Names	Protein Names
sushi domain-containing protein 3

SUSD3 Protein-protein interaction Information

Type	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	References
Intra	SUSD3	Q96L08	TMPRSS4	Homo sapiens	Q9NRS4	Validated Y2H	32296183
Intra	SUSD3	Q96L08	RPRM	Homo sapiens	Q9NS64	Validated Y2H	32296183
Intra	SUSD3	Q96L08	CLEC7A	Homo sapiens	Q9BXN2-6	Validated Y2H	32296183
Intra	SUSD3	Q96L08	TMEM47	Homo sapiens	Q9BQJ4	Validated Y2H	32296183
Intra	SUSD3	Q96L08	CGRRF1	Homo sapiens	Q99675	Validated Y2H	32296183
Intra	SUSD3	Q96L08	TMEM147	Homo sapiens	Q9BVK8	Validated Y2H	32296183
Intra	SUSD3	Q96L08	HHATL	Homo sapiens	Q9HCP6	Validated Y2H	32296183
Intra	SUSD3	Q96L08	TMEM98	Homo sapiens	Q9Y2Y6	Validated Y2H	32296183
Intra	SUSD3	Q96L08	SMCO4	Homo sapiens	Q9NRQ5	Validated Y2H	32296183

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases	Alias
Aarskog-Scott Syndrome	Aarskog Syndrome Faciogenital Dysplasia Faciodigitogenital Syndrome AAS Fgdy X-Linked Aarskog Syndrome Intellectual Developmental Disorder, X-Linked, Syndromic 16 Aarskog Syndrome, X-Linked Intellectual Developmental Disorder, X-Linked Syndromic 16 Greig'S Syndrome Aarskog Scott Syndrome Aarskog Disease Scott Aarskog Syndrome Facio-Digito-Genital Dysplasia Faciogenital Dysplasia With Attention Deficit-Hyperactivity Disorder Aarskog-Scott Syndrome ) Syndrome

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS14048	SUSD3 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS22840	Susd3 Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS29355	Susd3 Rat Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	SUSD3	VGNC	VGNC:78229
Mus musculus	SUSD3	MGD	MGI:1913579
Canis familiaris	SUSD3	VGNC	VGNC:46999
Rattus norvegicus	SUSD3	RGD	RGD:1310933
Bos taurus	SUSD3	VGNC	VGNC:35488
Felis catus	SUSD3	VGNC	VGNC:102992
Others	SUSD3	NCBI