LAPTM5 - lysosomal protein transmembrane 5 Gene

Homo sapiens

Also known as CLAST6

Gene ID: 7805 | Gene type: protein coding

About LAPTM5

Cytogenetic location: 1p35.2 Genomic coordinates (GRCh38): 1:30,732,469-30,757,774 (from NCBI)

This gene has 3 transcripts (splice variants), 115 orthologues and 2 paralogues. Broad expression in bone marrow (RPKM 488.0), lymph node (RPKM 349.3) and 15 other tissues.

Summary

This gene encodes a transmembrane receptor that is associated with lysosomes. The encoded protein, also known as E3 protein, may play a role in hematopoiesis. [provided by RefSeq, Feb 2009]

LAPTM5 Products(1)

mRNA	Protein	Name
NM_006762.3	NP_006753.1	lysosomal-associated transmembrane protein 5

LAPTM5 Protein Structure

Mtp

0
100
200
262 a.a.

Protein Preferred Names

Protein Names

lysosomal-associated transmembrane protein 5

CD40-ligand-activated specific transcripts

Related Diseases

Diseases

Alias

Pigmented Villonodular Synovitis

Diffuse Giant Cell Tumor Of Tenosynovium	Villous Tenosynovitis
Diffuse Pigmented Villonodular Synovitis	Diffuse-Type Gct
Diffuse-Type Giant Cell Tumor	Localized Pigmented Villonodular Synovitis
Tgct	Tsgct
Tenosynovial Giant Cell Tumor	Tenosynovial Giant Cell Tumors
Synovitis Pigmented Villonodular	Synovitis, Pigmented Villonodular
Fibrous Histiocytoma Of Tendon Sheath	Testicular Germ Cell Tumor
Chronic Haemorrhagic Villous Synovitis	Pvns - [Pigmented Villonodular Synovitis]
Villonodular Synovitis

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS07523	LAPTM5 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	LAPTM5	RGD	RGD:621838
Bos taurus	LAPTM5	VGNC	VGNC:30788
Canis familiaris	LAPTM5	VGNC	VGNC:42584
Macaca mulatta	LAPTM5	VGNC	VGNC:74162
Felis catus	LAPTM5	VGNC	VGNC:63190
Mus musculus	LAPTM5	MGD	MGI:108046

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