Search Result

No matches for "

64748

" within the MedChemExpress (MCE) catalog. Here are the results you might be looking for.

By Targets:	Apoptosis (6) Autophagy (6) Calcium Channel (2) Drug Derivative (1) Drug Intermediate (1) Fungal (1) Isotope-Labeled Compounds (3) MicroRNA (12) Reference Standards (2) VEGFR (6)
By Research Areas:	Cancer (18) Inflammation/Immunology (1) Neurological Disease (4)
Oligonucleotides:	miRNA mimics (3) miRNA antagomirs (3) miRNA agomirs (3) MicroRNAs (12) miRNA inhibitors (3)

Inhibitors & Agonists

Isotope-Labeled Compounds

Antibodies

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-10260

Vandetanib Maximum Cited Publications 27 Publications Verification ZD6474	VEGFR Autophagy Apoptosis	Neurological Disease Inflammation/Immunology Cancer
Vandetanib (D6474) is a potent, orally active, and blood-brain-barrier penetrate inhibitor of VEGFR2/KDR tyrosine kinase activity (IC₅₀=40 nM). Vandetanib also has activity versus the tyrosine kinase activity of VEGFR3/FLT4 (IC₅₀=110 nM) and EGFR/HER1 (IC₅₀=500 nM) .

HY-B0106A

Etiracetam UCB 6474	Drug Derivative	Neurological Disease
Etiracetam is a racetam-class nootropic agent. Etiracetam enhances learning and memory in both normal and amnesic rats. Etiracetam can be used in studies related to memory retrieval disorders and amnesic diseases such as Alzheimer's disease .

HY-15784

*NPPM 6748-481*	Fungal	Others
NPPM 6748-481 is a selective inhibitor of the yeast phosphatidylinositol transfer protein (PITP) Sec14 .

HY-10260B

Vandetanib hydrochloride ZD6474 hydrochloride	VEGFR Autophagy Apoptosis	Cancer
Vandetanib hydrochloride (D6474 hydrochloride) is a potent, orally active inhibitor of VEGFR2/KDR tyrosine kinase activity (IC₅₀=40 nM). Vandetanib hydrochloride also has activity versus the tyrosine kinase activity of VEGFR3/FLT4 (IC₅₀=110 nM) and EGFR/HER1 (IC₅₀=500 nM) .

HY-10260R

Vandetanib (Standard) ZD6474 (Standard)	Reference Standards VEGFR Autophagy Apoptosis	Cancer
Vandetanib (Standard) is the analytical standard of Vandetanib. This product is intended for research and analytical applications. Vandetanib (D6474) is a potent, orally active inhibitor of VEGFR2/KDR tyrosine kinase activity (IC₅₀=40 nM). Vandetanib also has activity versus the tyrosine kinase activity of VEGFR3/FLT4 (IC₅₀=110 nM) and EGFR/HER1 (IC₅₀=500 nM) .

HY-B0106AR

Etiracetam (Standard) UCB 6474 (Standard)	Reference Standards Calcium Channel	Neurological Disease
Etiracetam (Standard) is the analytical standard of Etiracetam. This product is intended for research and analytical applications. Etiracetam (UCB 6474) is an acetylcholine agonist and a nootropic drug of the racetam family. Less active than its S-enantiomer Levetiracetam (UCB L059) .

HY-W050216

TP-4748	Drug Intermediate	Others
TP-4748 is a building block in the chemical synthesis.

HY-10260A

Vandetanib trifluoroacetate ZD6474 trifluoroacetate	VEGFR Autophagy Apoptosis	Cancer
Vandetanib trifluoroacetate (D6474 trifluoroacetate) is a potent, orally active inhibitor of VEGFR2/KDR tyrosine kinase activity (IC₅₀=40 nM). Vandetanib trifluoroacetate also has activity versus the tyrosine kinase activity of VEGFR3/FLT4 (IC₅₀=110 nM) and EGFR/HER1 (IC₅₀=500 nM) .

HY-R02052A

*hsa-miR-6748-3p agomir*	MicroRNA	Cancer
hsa-miR-6748-3p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

hsa-miR-6748-3p agomir hsa-miR-6748-3p agomir

HY-R02052

*hsa-miR-6748-3p mimic*	MicroRNA	Cancer
hsa-miR-6748-3p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

hsa-miR-6748-3p mimic hsa-miR-6748-3p mimic

HY-R02053

*hsa-miR-6748-5p mimic*	MicroRNA	Cancer
hsa-miR-6748-5p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

hsa-miR-6748-5p mimic hsa-miR-6748-5p mimic

HY-RI02052

*hsa-miR-6748-3p inhibitor*	MicroRNA	Cancer
hsa-miR-6748-3p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

hsa-miR-6748-3p inhibitor hsa-miR-6748-3p inhibitor

HY-10260S

Vandetanib-d6 ZD6474-d₆	Isotope-Labeled Compounds VEGFR Autophagy Apoptosis	Cancer
Vandetanib-d₆ is the deuterium labeled Vandetanib. Vandetanib (D6474) is a potent, orally active inhibitor of VEGFR2/KDR tyrosine kinase activity (IC₅₀=40 nM). Vandetanib also has activity versus the tyrosine kinase activity of VEGFR3/FLT4 (IC₅₀=110 nM) and EGFR/HER1 (IC₅₀=500 nM) .

HY-B0106AS

Etiracetam-d3 UCB 6474-d₃	Isotope-Labeled Compounds Calcium Channel	Neurological Disease
Etiracetam-d₃ is the deuterium labeled Etiracetam. Etiracetam (UCB 6474) is an acetylcholine agonist and a nootropic drug of the racetam family. Less active than its S-enantiomer Levetiracetam (UCB L059) .

HY-10260S2

Vandetanib-13C6 ZD6474-¹³C₆	Isotope-Labeled Compounds VEGFR Autophagy Apoptosis	Cancer
Vandetanib- ¹³C₆ is a ¹³C labeled Vandetanib (HY-10260) . Vandetanib (D6474) is a potent, orally active inhibitor of VEGFR2/KDR tyrosine kinase activity (IC₅₀=40 nM). Vandetanib also has activity versus the tyrosine kinase activity of VEGFR3/FLT4 (IC₅₀=110 nM) and EGFR/HER1 (IC₅₀=500 nM) .

HY-RI01359

*hsa-miR-4748* inhibitor**	MicroRNA	Cancer
hsa-miR-4748 inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

hsa-miR-4748 inhibitor hsa-miR-4748 inhibitor

HY-R01359

*hsa-miR-4748* mimic**	MicroRNA	Cancer
hsa-miR-4748 mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

hsa-miR-4748 mimic hsa-miR-4748 mimic

HY-R01359A

*hsa-miR-4748* agomir**	MicroRNA	Cancer
hsa-miR-4748 agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

hsa-miR-4748 agomir hsa-miR-4748 agomir

HY-RI01359A

*hsa-miR-4748* antagomir**	MicroRNA	Cancer
hsa-miR-4748 antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

hsa-miR-4748 antagomir hsa-miR-4748 antagomir

HY-R02053A

*hsa-miR-6748-5p agomir*	MicroRNA	Cancer
hsa-miR-6748-5p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

hsa-miR-6748-5p agomir hsa-miR-6748-5p agomir

HY-RI02053

*hsa-miR-6748-5p inhibitor*	MicroRNA	Cancer
hsa-miR-6748-5p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

hsa-miR-6748-5p inhibitor hsa-miR-6748-5p inhibitor

HY-RI02053A

*hsa-miR-6748-5p antagomir*	MicroRNA	Cancer
hsa-miR-6748-5p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

hsa-miR-6748-5p antagomir hsa-miR-6748-5p antagomir

HY-RI02052A

*hsa-miR-6748-3p antagomir*	MicroRNA	Cancer
hsa-miR-6748-3p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

hsa-miR-6748-3p antagomir hsa-miR-6748-3p antagomir

Cat. No.	Product Name	Chemical Structure

HY-10260S

Vandetanib-d6
Vandetanib-d₆ is the deuterium labeled Vandetanib. Vandetanib (D6474) is a potent, orally active inhibitor of VEGFR2/KDR tyrosine kinase activity (IC₅₀=40 nM). Vandetanib also has activity versus the tyrosine kinase activity of VEGFR3/FLT4 (IC₅₀=110 nM) and EGFR/HER1 (IC₅₀=500 nM) .

HY-B0106AS

Etiracetam-d3
Etiracetam-d₃ is the deuterium labeled Etiracetam. Etiracetam (UCB 6474) is an acetylcholine agonist and a nootropic drug of the racetam family. Less active than its S-enantiomer Levetiracetam (UCB L059) .

HY-10260S2

Vandetanib-13C6
Vandetanib- ¹³C₆ is a ¹³C labeled Vandetanib (HY-10260) . Vandetanib (D6474) is a potent, orally active inhibitor of VEGFR2/KDR tyrosine kinase activity (IC₅₀=40 nM). Vandetanib also has activity versus the tyrosine kinase activity of VEGFR3/FLT4 (IC₅₀=110 nM) and EGFR/HER1 (IC₅₀=500 nM) .

Host:	Mouse (1) Rabbit (3)
Reactivity:	Human (4) Rat (1) Mouse (2)
Application:	IHC-P (4) ICC/IF (1) mIHC (1) IF-Tissue (2) WB (4) FC (1) ELISA (1)
Isotype:	IgG (3)
Conjugation:	Non-conjugated (4)
Clonality:	Monoclonal (4) Recombinant (3)
Modification:	Unmodified (4)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P85056

	BLK Antibody (YA4748) BLK; Tyrosine-protein kinase Blk; B lymphocyte kinase; p55-Blk	WB, IHC-P, ELISA	Human
	BLK Antibody (YA4748) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to BLK.

HY-P86785

	Aquaporin 5 Antibody (YA6478) AQP 5 antibody; AQP-5 antibody; AQP5 antibody; AQP5_HUMAN antibody; Aquaporin 5 antibody; Aquaporin-5 antibody;	WB, IHC-P, IF-Tissue, mIHC	Human, Mouse
	Aquaporin 5 Antibody (YA6478) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Aquaporin 5.

HY-P87055

	RPL13 Antibody (YA6748) 60S ribosomal protein L13 antibody; BBC1 antibody; Breast basic conserved gene 1 antibody; Breast basic conserved protein 1 antibody; D16S444E antibody; D16S44E antibody; FLJ27453 antibody; FLJ27454 antibody; L13 antibody; MGC117342 antibody; 60S ribosomal protein L13 antibody; BBC1 antibody; Breast basic conserved gene 1 antibody; Breast basic conserved protein 1 antibody; D16S444E antibody; D16S44E antibody; FLJ27453 antibody; FLJ27454 antibody; L13 antibody; MGC117342 antibody; MGC71373 antibody; OK/SW cl.46 antibody; OK/SWcl.46 antibody; Ribosomal protein L13 antibody; RL13_HUMAN antibody; rpl13 antibody;	WB, ICC/IF, IHC-P, IF-Tissue, FC	Human, Mouse, Rat
	RPL13 Antibody (YA6748) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to RPL13.

HY-P86781

	Alpha 1 Acid Glycoprotein Antibody (YA6474) A1AG1_HUMAN antibody; AGP 1 antibody; AGP A antibody; AGP antibody; AGP1 antibody; Alpha 1 acid glycoprotein antibody; Alpha-1-acid glycoprotein 1 antibody; alpha-1-AGP antibody; Epididymis secretory sperm binding protein Li 153w antibody; glycoprotein, alpha-1-acid, of serum antibody; A1AG1_HUMAN antibody; AGP 1 antibody; AGP A antibody; AGP antibody; AGP1 antibody; Alpha 1 acid glycoprotein antibody; Alpha-1-acid glycoprotein 1 antibody; alpha-1-AGP antibody; Epididymis secretory sperm binding protein Li 153w antibody; glycoprotein, alpha-1-acid, of serum antibody; HEL S 153w antibody; OMD 1 antibody; ORM antibody; ORM1 antibody; Orosomucoid 1 antibody; Orosomucoid-1 antibody;	WB, IHC-P	Human
	Alpha 1 Acid Glycoprotein Antibody (YA6474) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Alpha 1 Acid Glycoprotein.

Compare Products


Products	In-stock - + Add to Cart
Cat. No.
Host
Reactivity
Application
Dilution Ratio
Molecular Weight
Conjugation
Clonality
Immunogen
Appearance
Isotype
Gene ID
SwissProt ID
Purity
Formulation
Free Sample	Yes No
Size	* This product has been "discontinued". Optimized version of product available: / In-stock - + Add to Cart Get quote

Cat. No.	Product Name		Classification

HY-R02052A

*hsa-miR-6748-3p agomir*		MicroRNAs miRNA agomirs
hsa-miR-6748-3p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-R02052

*hsa-miR-6748-3p mimic*		MicroRNAs miRNA mimics
hsa-miR-6748-3p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

HY-R02053

*hsa-miR-6748-5p mimic*		MicroRNAs miRNA mimics
hsa-miR-6748-5p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

HY-RI02052

*hsa-miR-6748-3p inhibitor*		MicroRNAs miRNA inhibitors
hsa-miR-6748-3p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

HY-RI01359

*hsa-miR-4748* inhibitor**		MicroRNAs miRNA inhibitors
hsa-miR-4748 inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

HY-R01359

*hsa-miR-4748* mimic**		MicroRNAs miRNA mimics
hsa-miR-4748 mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

HY-R01359A

*hsa-miR-4748* agomir**		MicroRNAs miRNA agomirs
hsa-miR-4748 agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-RI01359A

*hsa-miR-4748* antagomir**		MicroRNAs miRNA antagomirs
hsa-miR-4748 antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-R02053A

*hsa-miR-6748-5p agomir*		MicroRNAs miRNA agomirs
hsa-miR-6748-5p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-RI02053

*hsa-miR-6748-5p inhibitor*		MicroRNAs miRNA inhibitors
hsa-miR-6748-5p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

HY-RI02053A

*hsa-miR-6748-5p antagomir*		MicroRNAs miRNA antagomirs
hsa-miR-6748-5p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-RI02052A

*hsa-miR-6748-3p antagomir*		MicroRNAs miRNA antagomirs
hsa-miR-6748-3p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

Inquiry Online

Submit your filled information, we will contact you soon.

Salutation:		* Country or Region:
* Applicant Name:		* Organization Name:
* Department:
* Email Address:		* Product Name:
Cat. No.:		* Requested quantity:
* Phone Number:
MCE Japan Authorized Agent:	ナミキ商事株式会社コスモ・バイオ株式会社重松貿易株式会社
Remarks:

Inquiry Online

Your information is safe with us. * Required Fields.

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社重松貿易株式会社
Salutation			Country or Region *
Applicant Name *			Organization Name *
Department *
Email Address *			Product Name *
Cat. No.			Requested quantity *
Phone Number *
Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent: