PLPPR2 - phospholipid phosphatase related 2 Gene

Also Known as PRG4; LPPR2

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 64748

Summary

Predicted to enable phosphatidate Phosphatase activity. Predicted to be involved in phospholipid dephosphorylation; phospholipid metabolic process; and signal transduction. Predicted to be located in membrane. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Jul 2025]
Ubiquitous expression in brain (RPKM 26.0), prostate (RPKM 12.8) and 25 other tissues.

PLPPR2 Products (7)

mRNA Protein Name
NM_001170635.2 NP_001164106.1 phospholipid phosphatase-related protein type 2 isoform 2
NM_001393892.1 NP_001380821.1 phospholipid phosphatase-related protein type 2 isoform 3
NM_001393893.1 NP_001380822.1 phospholipid phosphatase-related protein type 2 isoform 3
NM_001393894.1 NP_001380823.1 phospholipid phosphatase-related protein type 2 isoform 1
NM_001393895.1 NP_001380824.1 phospholipid phosphatase-related protein type 2 isoform 4
NM_001393896.1 NP_001380825.1 phospholipid phosphatase-related protein type 2 isoform 4
NM_022737.3 NP_073574.2 phospholipid phosphatase-related protein type 2 isoform 1

PLPPR2 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
PLPPR2 Q96GM1 MARCHF2 Homo sapiens Q9P0N8
Validated Y2H
32296183
Intra
PLPPR2 Q96GM1 CISD2 Homo sapiens Q8N5K1
Y2H Prey Pooling
32296183
Intra
PLPPR2 Q96GM1 CISD2 Homo sapiens Q8N5K1
Y2H Array
32296183
Intra
PLPPR2 Q96GM1 TMED9 Homo sapiens Q9BVK6
Validated Y2H
32296183
Intra
PLPPR2 Q96GM1 TMED9 Homo sapiens Q9BVK6
Y2H Array
32296183
Intra
PLPPR2 Q96GM1 TMED9 Homo sapiens Q9BVK6
Y2H Prey Pooling
32296183
Intra
PLPPR2 Q96GM1 TMEM237 Homo sapiens Q96Q45-2
Validated Y2H
32296183
Intra
PLPPR2 Q96GM1 TMEM237 Homo sapiens Q96Q45-2
Y2H Array
32296183
Intra
PLPPR2 Q96GM1 TMEM237 Homo sapiens Q96Q45-2
Y2H Prey Pooling
32296183
Intra
PLPPR2 Q96GM1 ARL13B Homo sapiens Q3SXY8
Y2H Array
32296183
Intra
PLPPR2 Q96GM1 ARL13B Homo sapiens Q3SXY8
Y2H Prey Pooling
32296183
Intra
PLPPR2 Q96GM1 LYPD5 Homo sapiens Q6UWN5
Y2H Prey Pooling
32296183
Intra
PLPPR2 Q96GM1 LYPD5 Homo sapiens Q6UWN5
Y2H Array
32296183
Intra
PLPPR2 Q96GM1 SCN3B Homo sapiens Q9NY72
Validated Y2H
32296183
Intra
PLPPR2 Q96GM1 SCN3B Homo sapiens Q9NY72
Y2H Prey Pooling
32296183
Intra
PLPPR2 Q96GM1 SCN3B Homo sapiens Q9NY72
Y2H Array
32296183
Intra
PLPPR2 Q96GM1 SSMEM1 Homo sapiens Q8WWF3
Y2H Array
32296183
Intra
PLPPR2 Q96GM1 SSMEM1 Homo sapiens Q8WWF3
Y2H Prey Pooling
32296183
Intra
PLPPR2 Q96GM1 SIGLEC12 Homo sapiens Q96PQ1
Y2H Array
32296183
Intra
PLPPR2 Q96GM1 SIGLEC12 Homo sapiens Q96PQ1
Validated Y2H
32296183
Intra
PLPPR2 Q96GM1 SIGLEC12 Homo sapiens Q96PQ1
Y2H Prey Pooling
32296183
Intra
PLPPR2 Q96GM1 CLDN5 Homo sapiens O00501
Y2H Array
32296183
Intra
PLPPR2 Q96GM1 CLDN5 Homo sapiens O00501
Y2H Prey Pooling
32296183
Intra
PLPPR2 Q96GM1 SLC19A3 Homo sapiens Q9BZV2
Validated Y2H
32296183
Intra
PLPPR2 Q96GM1 SLC19A3 Homo sapiens Q9BZV2
Y2H Array
32296183
Intra
PLPPR2 Q96GM1 SLC19A3 Homo sapiens Q9BZV2
Y2H Prey Pooling
32296183
Intra
PLPPR2 Q96GM1 CREB3L1 Homo sapiens Q96BA8
Y2H Array
32296183
Intra
PLPPR2 Q96GM1 CREB3L1 Homo sapiens Q96BA8
Y2H Prey Pooling
32296183
Intra
PLPPR2 Q96GM1 VSIR Homo sapiens Q9H7M9
Y2H Prey Pooling
32296183
Intra
PLPPR2 Q96GM1 VSIR Homo sapiens Q9H7M9
Validated Y2H
32296183
Intra
PLPPR2 Q96GM1 VSIR Homo sapiens Q9H7M9
Y2H Array
32296183
Intra
PLPPR2 Q96GM1 CIAO2A Homo sapiens Q9H5X1
Y2H Array
32296183
Intra
PLPPR2 Q96GM1 CIAO2A Homo sapiens Q9H5X1
Y2H Prey Pooling
32296183
Intra
PLPPR2 Q96GM1 CIAO2A Homo sapiens Q9H5X1
Validated Y2H
32296183
Intra
PLPPR2 Q96GM1 CD79A Homo sapiens P11912
Y2H Array
32296183
Intra
PLPPR2 Q96GM1 CD79A Homo sapiens P11912
Y2H Prey Pooling
32296183
Intra
PLPPR2 Q96GM1 KIR2DL3 Homo sapiens P43628
Y2H Prey Pooling
32296183
Intra
PLPPR2 Q96GM1 KIR2DL3 Homo sapiens P43628
Y2H Array
32296183
Intra
PLPPR2 Q96GM1 UBE2J1 Homo sapiens Q9Y385
Validated Y2H
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS10735 PLPP2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown