432020-20-7

NPPM 6748-481 Chemical Structure
432020-20-7

Chemical Structure

NPPM 6748-481

  • CAS No.: 432020-20-7
  • Formula:C17H15ClFN3O3
  • Molecular Weight:363.77

IUPAC Name: (4-chloro-3-nitrophenyl)(4-(2-fluorophenyl)piperazin-1-yl)methanone

InChIKey: LSPJXCGEFJDMHA-UHFFFAOYSA-N

SMILES: O=C(C1=CC=C(Cl)C([N+]([O-])=O)=C1)N2CCN(C3=CC=CC=C3F)CC2

Biological Activity: NPPM 6748-481 is a potent and selective yeast Sec14 inhibitor with a yeast Sec14 IC50 of 211 nM. NPPM 6748-481 disrupts membrane trafficking, impairing trans-Golgi network-endosomal transport and endocytic transport. NPPM 6748-481 impairs Snc1 v-SNARE recycling, secretory invertase trafficking, and vacuolar carboxypeptidase Y processing. NPPM 6748-481 can be used for research on yeast infection[1].

Cat. No. Product Name Purity Description Pricing
HY-15784
NPPM 6748-481 99.60% NPPM 6748-481 is a potent and selective yeast Sec14 inhibitor with a yeast Sec14 IC50 of 211 nM. NPPM 6748-481 disrupts membrane trafficking, impairing trans-Golgi network-endosomal transport and endocytic transport. NPPM 6748-481 impairs Snc1 v-SNARE recycling, secretory invertase trafficking, and vacuolar carboxypeptidase Y processing. NPPM 6748-481 can be used for research on yeast infection.
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