432020-20-7
Chemical Structure
NPPM 6748-481
- CAS No.: 432020-20-7
- Formula:C17H15ClFN3O3
- Molecular Weight:363.77
IUPAC Name: (4-chloro-3-nitrophenyl)(4-(2-fluorophenyl)piperazin-1-yl)methanone
InChIKey: LSPJXCGEFJDMHA-UHFFFAOYSA-N
SMILES: O=C(C1=CC=C(Cl)C([N+]([O-])=O)=C1)N2CCN(C3=CC=CC=C3F)CC2
Biological Activity: NPPM 6748-481 is a potent and selective yeast Sec14 inhibitor with a yeast Sec14 IC50 of 211 nM. NPPM 6748-481 disrupts membrane trafficking, impairing trans-Golgi network-endosomal transport and endocytic transport. NPPM 6748-481 impairs Snc1 v-SNARE recycling, secretory invertase trafficking, and vacuolar carboxypeptidase Y processing. NPPM 6748-481 can be used for research on yeast infection[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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NPPM 6748-481 | 99.60% | NPPM 6748-481 is a potent and selective yeast Sec14 inhibitor with a yeast Sec14 IC50 of 211 nM. NPPM 6748-481 disrupts membrane trafficking, impairing trans-Golgi network-endosomal transport and endocytic transport. NPPM 6748-481 impairs Snc1 v-SNARE recycling, secretory invertase trafficking, and vacuolar carboxypeptidase Y processing. NPPM 6748-481 can be used for research on yeast infection. | ||||||||||||||||||||
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