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Referencia número: HY-176431

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TLCD1-IN-1

TLCD1-IN-1 (compound MB-4A) is a covalent TLCD1 inhibitor. TLCD1-IN-1 stereoselectively engages and inhibits TLCD1 in HepG2 cells.

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Fòrmula: C₂₀H₁₉ClNO₅PS₂
Peso molecular:483.93

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

TLCD1-IN-1 Chemical Structure

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Actividad biológica

Descripciòn

TLCD1-IN-1 (compound MB-4A) is a covalent TLCD1 inhibitor. TLCD1-IN-1 stereoselectively engages and inhibits TLCD1 in HepG2 cells^[1].

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Chemical Information

Peso molecular 483.93
Fòrmula C₂₀H₁₉ClNO₅PS₂
SMILES

O=C(N1[C@H](COP2(SCCO2)=S)[C@@H](C3=CC=C(Cl)C=C3)C1)C4=CC=C(OCO5)C5=C4
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Sharma HA, et al. Proteomic Ligandability Maps of Phosphorus(V) Stereoprobes Identify Covalent TLCD1 Inhibitors. bioRxiv [Preprint]. 2025 Jan 31:2025.01.31.635883. [Content Brief]

Calculators

Calculadora de molaridad

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculadora de dilución

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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TLCD1-IN-1

Ver todos los productos específicos de isoformas Endogenous Metabolite

Actividad biológica

Descripciòn

Chemical Information

Pureza y Documentación

Referencias

Calculators

Help & FAQs

TLCD1-IN-1 Related Classifications

HY-176431 Related Classifications

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