TMEM86A - transmembrane protein 86A Gene

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 144110

About TMEM86A

This gene has 5 transcripts (splice variants), 198 orthologues and 1 paralogue. Ubiquitous expression in kidney (RPKM 12.8), skin (RPKM 8.6) and 23 other tissues.

Summary

Predicted to enable alkenylglycerophosphocholine hydrolase activity and alkenylglycerophosphoethanolamine hydrolase activity. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]

TMEM86A Products (1)

mRNA Protein Name
NM_153347.3 NP_699178.1 lysoplasmalogenase-like protein TMEM86A

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables alkenylglycerophosphocholine hydrolase activity IDA
IDA: Inferred from direct assay
36592658 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

TMEM86A Protein Structure

YhhN

YhhN: YhhN family (37 - 223)

  • 0
  • 100
  • 200
  • 240 a.a.
Protein Preferred Names Protein Names

lysoplasmalogenase-like protein TMEM86A

TMEM86A Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
TMEM86A Q8N2M4 NCAPH2 Homo sapiens Q6IBW4-4
Y2H Array
32296183
Intra
TMEM86A Q8N2M4 NCAPH2 Homo sapiens Q6IBW4-4
Y2H Prey Pooling
32296183
Intra
TMEM86A Q8N2M4 CISD2 Homo sapiens Q8N5K1
Validated Y2H
32296183
Intra
TMEM86A Q8N2M4 CISD2 Homo sapiens Q8N5K1
Y2H Array
32296183
Intra
TMEM86A Q8N2M4 CISD2 Homo sapiens Q8N5K1
Y2H Prey Pooling
32296183
Intra
TMEM86A Q8N2M4 PGRMC2 Homo sapiens O15173
Y2H Prey Pooling
32296183
Intra
TMEM86A Q8N2M4 PGRMC2 Homo sapiens O15173
Y2H Array
32296183
Intra
TMEM86A Q8N2M4 HAVCR2 Homo sapiens Q8TDQ0
Y2H Prey Pooling
32296183
Intra
TMEM86A Q8N2M4 HAVCR2 Homo sapiens Q8TDQ0
Validated Y2H
32296183
Intra
TMEM86A Q8N2M4 HAVCR2 Homo sapiens Q8TDQ0
Y2H Array
32296183
Intra
TMEM86A Q8N2M4 GJC1 Homo sapiens P36383
Y2H Prey Pooling
32296183
Intra
TMEM86A Q8N2M4 GJC1 Homo sapiens P36383
Y2H Array
32296183
Intra
TMEM86A Q8N2M4 FNDC9 Homo sapiens Q8TBE3
Y2H Prey Pooling
32296183
Intra
TMEM86A Q8N2M4 FNDC9 Homo sapiens Q8TBE3
Y2H Array
32296183
Intra
TMEM86A Q8N2M4 FNDC9 Homo sapiens Q8TBE3
Validated Y2H
32296183
Intra
TMEM86A Q8N2M4 FXYD3 Homo sapiens Q14802-3
Y2H Prey Pooling
32296183
Intra
TMEM86A Q8N2M4 FXYD3 Homo sapiens Q14802-3
Y2H Array
32296183
Intra
TMEM86A Q8N2M4 TMPRSS2 Homo sapiens O15393-2
Y2H Prey Pooling
32296183
Intra
TMEM86A Q8N2M4 TMPRSS2 Homo sapiens O15393-2
Y2H Array
32296183
Intra
TMEM86A Q8N2M4 RIC3 Homo sapiens Q7Z5B4-5
Y2H Array
32296183
Intra
TMEM86A Q8N2M4 RIC3 Homo sapiens Q7Z5B4-5
Y2H Prey Pooling
32296183
Intra
TMEM86A Q8N2M4 AQP2 Homo sapiens P41181
Y2H Prey Pooling
32296183
Intra
TMEM86A Q8N2M4 AQP2 Homo sapiens P41181
Y2H Array
32296183
Intra
TMEM86A Q8N2M4 PI16 Homo sapiens Q6UXB8
Y2H Array
32296183
Intra
TMEM86A Q8N2M4 PI16 Homo sapiens Q6UXB8
Y2H Prey Pooling
32296183
Intra
TMEM86A Q8N2M4 GJB4 Homo sapiens Q9NTQ9
Y2H Array
32296183
Intra
TMEM86A Q8N2M4 GJB4 Homo sapiens Q9NTQ9
Validated Y2H
32296183
Intra
TMEM86A Q8N2M4 GJB4 Homo sapiens Q9NTQ9
Y2H Prey Pooling
32296183
Intra
TMEM86A Q8N2M4 SLC39A2 Homo sapiens Q9NP94
Y2H Prey Pooling
32296183
Intra
TMEM86A Q8N2M4 SLC39A2 Homo sapiens Q9NP94
Validated Y2H
32296183
Intra
TMEM86A Q8N2M4 SLC39A2 Homo sapiens Q9NP94
Y2H Array
32296183
Intra
TMEM86A Q8N2M4 MS4A2 Homo sapiens Q01362
Y2H Prey Pooling
32296183
Intra
TMEM86A Q8N2M4 MS4A2 Homo sapiens Q01362
Y2H Array
32296183
Intra
TMEM86A Q8N2M4 SCN3B Homo sapiens Q9NY72
Validated Y2H
32296183
Intra
TMEM86A Q8N2M4 SCN3B Homo sapiens Q9NY72
Y2H Array
32296183
Intra
TMEM86A Q8N2M4 SCN3B Homo sapiens Q9NY72
Y2H Prey Pooling
32296183
Intra
TMEM86A Q8N2M4 MUC1 Homo sapiens P15941-11
Y2H Prey Pooling
32296183
Intra
TMEM86A Q8N2M4 MUC1 Homo sapiens P15941-11
Y2H Array
32296183
Intra
TMEM86A Q8N2M4 SSMEM1 Homo sapiens Q8WWF3
Y2H Prey Pooling
32296183
Intra
TMEM86A Q8N2M4 SSMEM1 Homo sapiens Q8WWF3
Y2H Array
32296183
Intra
TMEM86A Q8N2M4 SSMEM1 Homo sapiens Q8WWF3
Validated Y2H
32296183
Intra
TMEM86A Q8N2M4 SLC35C2 Homo sapiens Q9NQQ7-3
Validated Y2H
32296183
Intra
TMEM86A Q8N2M4 SLC35C2 Homo sapiens Q9NQQ7-3
Y2H Prey Pooling
32296183
Intra
TMEM86A Q8N2M4 SLC35C2 Homo sapiens Q9NQQ7-3
Y2H Array
32296183
Intra
TMEM86A Q8N2M4 SLC18A1 Homo sapiens P54219-3
Y2H Array
32296183
Intra
TMEM86A Q8N2M4 SLC18A1 Homo sapiens P54219-3
Y2H Prey Pooling
32296183
Intra
TMEM86A Q8N2M4 CPLX4 Homo sapiens Q7Z7G2
Y2H Prey Pooling
32296183
Intra
TMEM86A Q8N2M4 CPLX4 Homo sapiens Q7Z7G2
Y2H Array
32296183
Intra
TMEM86A Q8N2M4 SLC10A6 Homo sapiens Q3KNW5
Y2H Prey Pooling
32296183
Intra
TMEM86A Q8N2M4 SLC10A6 Homo sapiens Q3KNW5
Y2H Array
32296183
Intra
TMEM86A Q8N2M4 FAM209A Homo sapiens Q5JX71
Y2H Prey Pooling
32296183
Intra
TMEM86A Q8N2M4 FAM209A Homo sapiens Q5JX71
Y2H Array
32296183
Intra
TMEM86A Q8N2M4 TYROBP Homo sapiens O43914
Y2H Prey Pooling
32296183
Intra
TMEM86A Q8N2M4 TYROBP Homo sapiens O43914
Y2H Array
32296183
Intra
TMEM86A Q8N2M4 RNF185 Homo sapiens Q96GF1
Y2H Array
32296183
Intra
TMEM86A Q8N2M4 RNF185 Homo sapiens Q96GF1
Y2H Prey Pooling
32296183
Intra
TMEM86A Q8N2M4 RNF185 Homo sapiens Q96GF1
Validated Y2H
32296183
Intra
TMEM86A Q8N2M4 AQP3 Homo sapiens Q92482
Y2H Prey Pooling
32296183
Intra
TMEM86A Q8N2M4 AQP3 Homo sapiens Q92482
Validated Y2H
32296183
Intra
TMEM86A Q8N2M4 AQP3 Homo sapiens Q92482
Y2H Array
32296183
Intra
TMEM86A Q8N2M4 LHFPL5 Homo sapiens Q8TAF8
Y2H Array
32296183
Intra
TMEM86A Q8N2M4 LHFPL5 Homo sapiens Q8TAF8
Validated Y2H
32296183
Intra
TMEM86A Q8N2M4 LHFPL5 Homo sapiens Q8TAF8
Y2H Prey Pooling
32296183
Intra
TMEM86A Q8N2M4 FFAR2 Homo sapiens O15552
Y2H Array
32296183
Intra
TMEM86A Q8N2M4 FFAR2 Homo sapiens O15552
Y2H Prey Pooling
32296183
Intra
TMEM86A Q8N2M4 CNR2 Homo sapiens P34972
Y2H Prey Pooling
32296183
Intra
TMEM86A Q8N2M4 CNR2 Homo sapiens P34972
Y2H Array
32296183
Intra
TMEM86A Q8N2M4 GPR37L1 Homo sapiens O60883
Y2H Array
32296183
Intra
TMEM86A Q8N2M4 GPR37L1 Homo sapiens O60883
Y2H Prey Pooling
32296183
Intra
TMEM86A Q8N2M4 GJB5 Homo sapiens O95377
Y2H Prey Pooling
32296183
Intra
TMEM86A Q8N2M4 GJB5 Homo sapiens O95377
Y2H Array
32296183
Intra
TMEM86A Q8N2M4 EBP Homo sapiens Q15125
Y2H Array
32296183
Intra
TMEM86A Q8N2M4 EBP Homo sapiens Q15125
Y2H Prey Pooling
32296183
Intra
TMEM86A Q8N2M4 GORAB Homo sapiens Q5T7V8
Y2H Prey Pooling
32296183
Intra
TMEM86A Q8N2M4 GORAB Homo sapiens Q5T7V8
Y2H Array
32296183
Intra
TMEM86A Q8N2M4 FKBP7 Homo sapiens Q9Y680
Validated Y2H
32296183
Intra
TMEM86A Q8N2M4 FKBP7 Homo sapiens Q9Y680
Y2H Prey Pooling
32296183
Intra
TMEM86A Q8N2M4 FKBP7 Homo sapiens Q9Y680
Y2H Array
32296183
Intra
TMEM86A Q8N2M4 TIMMDC1 Homo sapiens Q9NPL8
Y2H Prey Pooling
32296183
Intra
TMEM86A Q8N2M4 TIMMDC1 Homo sapiens Q9NPL8
Y2H Array
32296183
Intra
TMEM86A Q8N2M4 TIMMDC1 Homo sapiens Q9NPL8
Validated Y2H
32296183
Intra
TMEM86A Q8N2M4 CREB3L1 Homo sapiens Q96BA8
Validated Y2H
32296183
Intra
TMEM86A Q8N2M4 CREB3L1 Homo sapiens Q96BA8
Y2H Array
32296183
Intra
TMEM86A Q8N2M4 CREB3L1 Homo sapiens Q96BA8
Y2H Prey Pooling
32296183
Intra
TMEM86A Q8N2M4 PDZK1IP1 Homo sapiens Q13113
Y2H Prey Pooling
32296183
Intra
TMEM86A Q8N2M4 PDZK1IP1 Homo sapiens Q13113
Y2H Array
32296183
Intra
TMEM86A Q8N2M4 COQ9 Homo sapiens O75208
Y2H Prey Pooling
32296183
Intra
TMEM86A Q8N2M4 COQ9 Homo sapiens O75208
Y2H Array
32296183
Intra
TMEM86A Q8N2M4 THAP4 Homo sapiens Q8WY91
Validated Y2H
32296183
Intra
TMEM86A Q8N2M4 THAP4 Homo sapiens Q8WY91
Y2H Prey Pooling
32296183
Intra
TMEM86A Q8N2M4 THAP4 Homo sapiens Q8WY91
Y2H Array
32296183
Intra
TMEM86A Q8N2M4 BCL2L13 Homo sapiens Q9BXK5
Y2H Prey Pooling
32296183
Intra
TMEM86A Q8N2M4 BCL2L13 Homo sapiens Q9BXK5
Validated Y2H
32296183
Intra
TMEM86A Q8N2M4 BCL2L13 Homo sapiens Q9BXK5
Y2H Array
32296183
Intra
TMEM86A Q8N2M4 KASH5 Homo sapiens Q8N6L0
Y2H Array
32296183
Intra
TMEM86A Q8N2M4 KASH5 Homo sapiens Q8N6L0
Y2H Prey Pooling
32296183
Intra
TMEM86A Q8N2M4 KASH5 Homo sapiens Q8N6L0
Validated Y2H
32296183
Intra
TMEM86A Q8N2M4 REEP4 Homo sapiens Q9H6H4
Y2H Prey Pooling
32296183
Intra
TMEM86A Q8N2M4 REEP4 Homo sapiens Q9H6H4
Validated Y2H
32296183
Intra
TMEM86A Q8N2M4 REEP4 Homo sapiens Q9H6H4
Y2H Array
32296183
Intra
TMEM86A Q8N2M4 CD79A Homo sapiens P11912
Y2H Prey Pooling
32296183
Intra
TMEM86A Q8N2M4 CD79A Homo sapiens P11912
Y2H Array
32296183
Intra
TMEM86A Q8N2M4 ERGIC3 Homo sapiens Q9Y282
Y2H Prey Pooling
32296183
Intra
TMEM86A Q8N2M4 ERGIC3 Homo sapiens Q9Y282
Validated Y2H
32296183
Intra
TMEM86A Q8N2M4 ERGIC3 Homo sapiens Q9Y282
Y2H Array
32296183
Intra
TMEM86A Q8N2M4 KCNA1 Homo sapiens Q09470
Y2H Array
32296183
Intra
TMEM86A Q8N2M4 KCNA1 Homo sapiens Q09470
Y2H Prey Pooling
32296183
Intra
TMEM86A Q8N2M4 SLC30A2 Homo sapiens Q9BRI3
Validated Y2H
32296183
Intra
TMEM86A Q8N2M4 SLC30A2 Homo sapiens Q9BRI3
Y2H Prey Pooling
32296183
Intra
TMEM86A Q8N2M4 SLC30A2 Homo sapiens Q9BRI3
Y2H Array
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14743 TMEM86A Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus TMEM86A RGD RGD:1305749
Felis catus TMEM86A VGNC VGNC:66366
Bos taurus TMEM86A VGNC VGNC:36116
Macaca mulatta TMEM86A VGNC VGNC:101415
Canis familiaris TMEM86A VGNC VGNC:47608
Mus musculus TMEM86A MGD MGI:1915143
Others TMEM86A NCBI