MS4A12 - membrane spanning 4-domains A12 Gene
Also Known as Ms4a10
Species: Homo sapiens
Gene Type: protein coding
Gene ID: 54860
Summary
The protein encoded by this gene is a cell surface protein found primarily in the apical membrane of colonocytes. Silencing of this gene in colon Cancer cells inhibits the proliferation, cell motility, and chemotactic invasion of cells. This gene is part of a cluster of similar genes found on chromosome 11. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2009]
Restricted expression toward colon (RPKM 119.7).
MS4A12 Products (2)
| mRNA | Protein | Name |
|---|---|---|
| NM_001164470.2 | NP_001157942.1 | membrane-spanning 4-domains subfamily A member 12 isoform 2 |
| NM_017716.3 | NP_060186.2 | membrane-spanning 4-domains subfamily A member 12 isoform 1 |
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MS4A12 Protein-protein interaction Information
|
Type
|
Protein Name | Protein ID | Interactor | Interactor Species | Interactor ID | Detection Method | References |
|---|---|---|---|---|---|---|---|
|
Intra
|
MS4A12 | Q9NXJ0 | FAM3A | Homo sapiens | Q9BU27 | 25416956 | |
|
Intra
|
MS4A12 | Q9NXJ0 | FAM3A | Homo sapiens | Q9BU27 | 25416956 | |
|
Intra
|
MS4A12 | Q9NXJ0 | PLLP | Homo sapiens | Q9Y342 | 25416956 | |
|
Intra
|
MS4A12 | Q9NXJ0 | PLLP | Homo sapiens | Q9Y342 | 32296183 | |
|
Intra
|
MS4A12 | Q9NXJ0 | MALL | Homo sapiens | Q13021 | 25416956 | |
|
Intra
|
MS4A12 | Q9NXJ0 | MALL | Homo sapiens | Q13021 | 25416956 |
Cross: Cross-species interaction
Intra: Intraspecies interaction