MALL - mal, T cell differentiation protein like Gene

Also Known as BENE

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 7851

About MALL

Cytogenetic location: 2q13 Genomic coordinates (GRCh38): 2:110,083,870-110,118,139 (from NCBI)

This gene has 3 transcripts (splice variants), 126 orthologues and 14 paralogues. Biased expression in esophagus (RPKM 101.4), duodenum (RPKM 83.6) and 10 other tissues.

Summary

This gene encodes an element of the machinery for raft-mediated trafficking in endothelial cells. The encoded protein, a member of the MAL proteolipid family, predominantly localizes in glycolipid- and cholesterol-enriched membrane (GEM) rafts. It interacts with caveolin-1. [provided by RefSeq, Jul 2008]

MALL Products (3)

mRNA Protein Name
NM_001371559.1 NP_001358488.1 MAL-like protein isoform 2
NM_001371560.1 NP_001358489.1 MAL-like protein isoform 3
NM_005434.5 NP_005425.1 MAL-like protein isoform 1

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
11294831 GOA
Cellular Component GO Annotation Evidence References Source
located in Golgi membrane IDA
IDA: Inferred from direct assay
11294831 GOA
located in clathrin-coated vesicle IDA
IDA: Inferred from direct assay
11294831 GOA
located in cytoplasmic vesicle IDA
IDA: Inferred from direct assay
11294831 GOA
located in membrane raft IDA
IDA: Inferred from direct assay
11294831 GOA
located in plasma membrane IDA
IDA: Inferred from direct assay
11294831 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

MALL Protein Structure

MARVEL

MARVEL: Membrane-associating domain (26 - 148)

  • 0
  • 100
  • 153 a.a.
Protein Preferred Names Protein Names

MAL-like protein

MALL Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
MALL Q13021 LDLRAD1 Homo sapiens Q5T700
Y2H Array
32296183
Intra
MALL Q13021 LDLRAD1 Homo sapiens Q5T700
Y2H Prey Pooling
25416956
Intra
MALL Q13021 LDLRAD1 Homo sapiens Q5T700
Y2H Prey Pooling
32296183
Intra
MALL Q13021 LDLRAD1 Homo sapiens Q5T700
Y2H Array
31515488
Intra
MALL Q13021 LDLRAD1 Homo sapiens Q5T700
Validated Y2H
25416956
Intra
MALL Q13021 LDLRAD1 Homo sapiens Q5T700
Validated Y2H
32296183
Intra
MALL Q13021 UBE2I Homo sapiens Q7KZS0
Y2H Prey Pooling
32296183
Intra
MALL Q13021 UBE2I Homo sapiens Q7KZS0
Validated Y2H
32296183
Intra
MALL Q13021 UBE2I Homo sapiens Q7KZS0
Y2H Array
32296183
Intra
MALL Q13021 RETREG3 Homo sapiens Q86VR2
Y2H Prey Pooling
32296183
Intra
MALL Q13021 RETREG3 Homo sapiens Q86VR2
Validated Y2H
32296183
Intra
MALL Q13021 RETREG3 Homo sapiens Q86VR2
Y2H Array
32296183
Intra
MALL Q13021 MS4A12 Homo sapiens Q9NXJ0
Validated Y2H
25416956
Intra
MALL Q13021 MS4A12 Homo sapiens Q9NXJ0
Y2H Prey Pooling
32296183
Intra
MALL Q13021 MS4A12 Homo sapiens Q9NXJ0
Validated Y2H
32296183
Intra
MALL Q13021 MS4A12 Homo sapiens Q9NXJ0
Y2H Array
32296183
Intra
MALL Q13021 TMEM182 Homo sapiens Q6ZP80
Validated Y2H
32296183
Intra
MALL Q13021 TMEM182 Homo sapiens Q6ZP80
Y2H Array
32296183
Intra
MALL Q13021 TMEM182 Homo sapiens Q6ZP80
Y2H Prey Pooling
32296183
Intra
MALL Q13021 CTLA4 Homo sapiens P16410
Y2H Array
32296183
Intra
MALL Q13021 CTLA4 Homo sapiens P16410
Y2H Prey Pooling
32296183
Intra
MALL Q13021 TMEM248 Homo sapiens Q9NWD8
Validated Y2H
32296183
Intra
MALL Q13021 TMEM248 Homo sapiens Q9NWD8
Y2H Prey Pooling
32296183
Intra
MALL Q13021 TMEM248 Homo sapiens Q9NWD8
Y2H Array
32296183
Intra
MALL Q13021 PGRMC2 Homo sapiens O15173
Y2H Prey Pooling
32296183
Intra
MALL Q13021 PGRMC2 Homo sapiens O15173
Y2H Array
32296183
Intra
MALL Q13021 GGT7 Homo sapiens Q9UJ14
Validated Y2H
25416956
Intra
MALL Q13021 GGT7 Homo sapiens Q9UJ14
Y2H Prey Pooling
32296183
Intra
MALL Q13021 GGT7 Homo sapiens Q9UJ14
Validated Y2H
32296183
Intra
MALL Q13021 GGT7 Homo sapiens Q9UJ14
Y2H Array
32296183
Intra
MALL Q13021 ARL13B Homo sapiens Q3SXY8
Validated Y2H
32296183
Intra
MALL Q13021 ARL13B Homo sapiens Q3SXY8
Y2H Array
32296183
Intra
MALL Q13021 ARL13B Homo sapiens Q3SXY8
Y2H Prey Pooling
32296183
Intra
MALL Q13021 BSCL2 Homo sapiens J3KQ12
Y2H Array
32296183
Intra
MALL Q13021 TMEM80 Homo sapiens Q96HE8
Y2H Prey Pooling
32296183
Intra
MALL Q13021 TMEM80 Homo sapiens Q96HE8
Validated Y2H
32296183
Intra
MALL Q13021 TMEM80 Homo sapiens Q96HE8
Y2H Array
32296183
Intra
MALL Q13021 SYNE4 Homo sapiens Q8N205-2
Validated Y2H
32296183
Intra
MALL Q13021 SYNE4 Homo sapiens Q8N205-2
Y2H Array
32296183
Intra
MALL Q13021 SYNE4 Homo sapiens Q8N205-2
Y2H Prey Pooling
32296183
Intra
MALL Q13021 DCBLD2 Homo sapiens Q96PD2-2
Y2H Array
32296183
Intra
MALL Q13021 DCBLD2 Homo sapiens Q96PD2-2
Y2H Prey Pooling
32296183
Intra
MALL Q13021 DCBLD2 Homo sapiens Q96PD2-2
Validated Y2H
32296183
Intra
MALL Q13021 FNDC9 Homo sapiens Q8TBE3
Y2H Prey Pooling
32296183
Intra
MALL Q13021 FNDC9 Homo sapiens Q8TBE3
Validated Y2H
32296183
Intra
MALL Q13021 FNDC9 Homo sapiens Q8TBE3
Y2H Array
32296183
Intra
MALL Q13021 SIGLEC6 Homo sapiens O43699-3
Y2H Array
32296183
Intra
MALL Q13021 SIGLEC6 Homo sapiens O43699-3
Y2H Prey Pooling
32296183
Intra
MALL Q13021 OPRM1 Homo sapiens P35372-10
Y2H Array
32296183
Intra
MALL Q13021 OPRM1 Homo sapiens P35372-10
Y2H Prey Pooling
32296183
Intra
MALL Q13021 DAGLA Homo sapiens Q9Y4D2
Y2H Array
32296183
Intra
MALL Q13021 DAGLA Homo sapiens Q9Y4D2
Y2H Prey Pooling
32296183
Intra
MALL Q13021 DAGLA Homo sapiens Q9Y4D2
Validated Y2H
32296183
Intra
MALL Q13021 CLEC12B Homo sapiens Q2HXU8-2
Y2H Prey Pooling
32296183
Intra
MALL Q13021 CLEC12B Homo sapiens Q2HXU8-2
Validated Y2H
32296183
Intra
MALL Q13021 CLEC12B Homo sapiens Q2HXU8-2
Y2H Array
32296183
Intra
MALL Q13021 AQP6 Homo sapiens Q13520
Validated Y2H
32296183
Intra
MALL Q13021 AQP6 Homo sapiens Q13520
Y2H Array
32296183
Intra
MALL Q13021 AQP6 Homo sapiens Q13520
Y2H Prey Pooling
32296183
Intra
MALL Q13021 PLA2G2E Homo sapiens Q9NZK7
Y2H Prey Pooling
32296183
Intra
MALL Q13021 PLA2G2E Homo sapiens Q9NZK7
Validated Y2H
32296183
Intra
MALL Q13021 PLA2G2E Homo sapiens Q9NZK7
Y2H Array
32296183
Intra
MALL Q13021 ELOVL2 Homo sapiens Q9NXB9
Y2H Array
32296183
Intra
MALL Q13021 ELOVL2 Homo sapiens Q9NXB9
Y2H Prey Pooling
32296183
Intra
MALL Q13021 ELOVL2 Homo sapiens Q9NXB9
Validated Y2H
32296183
Intra
MALL Q13021 MUC1 Homo sapiens P15941-11
Y2H Prey Pooling
32296183
Intra
MALL Q13021 MUC1 Homo sapiens P15941-11
Y2H Array
32296183
Intra
MALL Q13021 SLC35C2 Homo sapiens Q9NQQ7-3
Y2H Prey Pooling
32296183
Intra
MALL Q13021 SLC35C2 Homo sapiens Q9NQQ7-3
Y2H Array
32296183
Intra
MALL Q13021 SLC35C2 Homo sapiens Q9NQQ7-3
Validated Y2H
32296183
Intra
MALL Q13021 ZP3 Homo sapiens P21754-3
Y2H Prey Pooling
32296183
Intra
MALL Q13021 ZP3 Homo sapiens P21754-3
Y2H Array
32296183
Intra
MALL Q13021 GJA8 Homo sapiens P48165
Y2H Array
32296183
Intra
MALL Q13021 GJA8 Homo sapiens P48165
Y2H Prey Pooling
32296183
Intra
MALL Q13021 SLC18A1 Homo sapiens P54219-3
Y2H Array
32296183
Intra
MALL Q13021 SLC18A1 Homo sapiens P54219-3
Y2H Prey Pooling
32296183
Intra
MALL Q13021 CLEC14A Homo sapiens Q86T13
Validated Y2H
32296183
Intra
MALL Q13021 CLEC14A Homo sapiens Q86T13
Y2H Array
32296183
Intra
MALL Q13021 MSR1 Homo sapiens P21757
Y2H Prey Pooling
32296183
Intra
MALL Q13021 MSR1 Homo sapiens P21757
Y2H Array
32296183
Intra
MALL Q13021 MSR1 Homo sapiens P21757
Y2H Prey Pooling
25416956
Intra
MALL Q13021 CPLX4 Homo sapiens Q7Z7G2
Y2H Prey Pooling
32296183
Intra
MALL Q13021 CPLX4 Homo sapiens Q7Z7G2
Validated Y2H
32296183
Intra
MALL Q13021 CPLX4 Homo sapiens Q7Z7G2
Y2H Array
32296183
Intra
MALL Q13021 SLC10A6 Homo sapiens Q3KNW5
Y2H Prey Pooling
32296183
Intra
MALL Q13021 SLC10A6 Homo sapiens Q3KNW5
Validated Y2H
32296183
Intra
MALL Q13021 SLC10A6 Homo sapiens Q3KNW5
Y2H Array
32296183
Intra
MALL Q13021 CLDN9 Homo sapiens O95484
Y2H Prey Pooling
32296183
Intra
MALL Q13021 CLDN9 Homo sapiens O95484
Y2H Array
32296183
Intra
MALL Q13021 ELOVL4 Homo sapiens Q9GZR5
Y2H Array
32296183
Intra
MALL Q13021 ELOVL4 Homo sapiens Q9GZR5
Y2H Prey Pooling
32296183
Intra
MALL Q13021 ELOVL4 Homo sapiens Q9GZR5
Validated Y2H
32296183
Intra
MALL Q13021 AMIGO1 Homo sapiens Q86WK6
Validated Y2H
32296183
Intra
MALL Q13021 AMIGO1 Homo sapiens Q86WK6
Y2H Prey Pooling
32296183
Intra
MALL Q13021 AMIGO1 Homo sapiens Q86WK6
Y2H Array
32296183
Intra
MALL Q13021 BEST2 Homo sapiens Q8NFU1
Validated Y2H
32296183
Intra
MALL Q13021 BEST2 Homo sapiens Q8NFU1
Y2H Array
32296183
Intra
MALL Q13021 BEST2 Homo sapiens Q8NFU1
Y2H Prey Pooling
32296183
Intra
MALL Q13021 STMN4 Homo sapiens Q9H169-2
Y2H Array
32296183
Intra
MALL Q13021 STMN4 Homo sapiens Q9H169-2
Y2H Prey Pooling
32296183
Intra
MALL Q13021 STMN4 Homo sapiens Q9H169-2
Validated Y2H
32296183
Intra
MALL Q13021 RNF185 Homo sapiens Q96GF1
Y2H Prey Pooling
32296183
Intra
MALL Q13021 RNF185 Homo sapiens Q96GF1
Validated Y2H
32296183
Intra
MALL Q13021 RNF185 Homo sapiens Q96GF1
Y2H Array
32296183
Intra
MALL Q13021 CRHR2 Homo sapiens Q13324-2
Y2H Array
32296183
Intra
MALL Q13021 CRHR2 Homo sapiens Q13324-2
Validated Y2H
32296183
Intra
MALL Q13021 CRHR2 Homo sapiens Q13324-2
Y2H Prey Pooling
32296183
Intra
MALL Q13021 ATP5PF Homo sapiens P18859
Y2H Prey Pooling
32296183
Intra
MALL Q13021 ATP5PF Homo sapiens P18859
Y2H Array
32296183
Intra
MALL Q13021 MCEMP1 Homo sapiens Q8IX19
Y2H Prey Pooling
32296183
Intra
MALL Q13021 MCEMP1 Homo sapiens Q8IX19
Validated Y2H
32296183
Intra
MALL Q13021 MCEMP1 Homo sapiens Q8IX19
Y2H Array
32296183
Intra
MALL Q13021 FFAR2 Homo sapiens O15552
Y2H Array
32296183
Intra
MALL Q13021 FFAR2 Homo sapiens O15552
Y2H Prey Pooling
32296183
Intra
MALL Q13021 FCGR1A Homo sapiens P12314
Y2H Prey Pooling
32296183
Intra
MALL Q13021 FCGR1A Homo sapiens P12314
Y2H Array
32296183
Intra
MALL Q13021 EVI2A Homo sapiens P22794
Y2H Array
32296183
Intra
MALL Q13021 EVI2A Homo sapiens P22794
Y2H Prey Pooling
32296183
Intra
MALL Q13021 CLEC10A Homo sapiens Q8IUN9
Y2H Array
32296183
Intra
MALL Q13021 CLEC10A Homo sapiens Q8IUN9
Y2H Prey Pooling
32296183
Intra
MALL Q13021 CLEC10A Homo sapiens Q8IUN9
Validated Y2H
32296183
Intra
MALL Q13021 BRI3 Homo sapiens O95415
Y2H Prey Pooling
32296183
Intra
MALL Q13021 BRI3 Homo sapiens O95415
Y2H Array
32296183
Intra
MALL Q13021 MANBAL Homo sapiens Q9NQG1
Y2H Prey Pooling
32296183
Intra
MALL Q13021 MANBAL Homo sapiens Q9NQG1
Validated Y2H
32296183
Intra
MALL Q13021 MANBAL Homo sapiens Q9NQG1
Y2H Array
32296183
Intra
MALL Q13021 SLC10A1 Homo sapiens Q14973
Y2H Prey Pooling
32296183
Intra
MALL Q13021 SLC10A1 Homo sapiens Q14973
Validated Y2H
32296183
Intra
MALL Q13021 SLC10A1 Homo sapiens Q14973
Y2H Array
32296183
Intra
MALL Q13021 GPA33 Homo sapiens Q99795
Y2H Array
32296183
Intra
MALL Q13021 GPA33 Homo sapiens Q99795
Validated Y2H
32296183
Intra
MALL Q13021 GPA33 Homo sapiens Q99795
Y2H Prey Pooling
32296183
Intra
MALL Q13021 EMP1 Homo sapiens P54849
Y2H Prey Pooling
32296183
Intra
MALL Q13021 EMP1 Homo sapiens P54849
Y2H Array
32296183
Intra
MALL Q13021 TMX2 Homo sapiens Q9Y320
Y2H Prey Pooling
32296183
Intra
MALL Q13021 TMX2 Homo sapiens Q9Y320
Validated Y2H
32296183
Intra
MALL Q13021 TMX2 Homo sapiens Q9Y320
Y2H Array
32296183
Intra
MALL Q13021 CREB3L1 Homo sapiens Q96BA8
Y2H Array
32296183
Intra
MALL Q13021 CREB3L1 Homo sapiens Q96BA8
Validated Y2H
32296183
Intra
MALL Q13021 CREB3L1 Homo sapiens Q96BA8
Y2H Prey Pooling
32296183
Intra
MALL Q13021 SIT1 Homo sapiens Q9Y3P8
Y2H Prey Pooling
32296183
Intra
MALL Q13021 SIT1 Homo sapiens Q9Y3P8
Validated Y2H
32296183
Intra
MALL Q13021 SIT1 Homo sapiens Q9Y3P8
Y2H Array
32296183
Intra
MALL Q13021 STX1A Homo sapiens Q16623
Validated Y2H
32296183
Intra
MALL Q13021 STX1A Homo sapiens Q16623
Y2H Prey Pooling
32296183
Intra
MALL Q13021 STX1A Homo sapiens Q16623
Y2H Array
32296183
Intra
MALL Q13021 SYNE4 Homo sapiens Q8N205
Y2H Array
25416956
Intra
MALL Q13021 TMEM139 Homo sapiens Q8IV31
Y2H Array
32296183
Intra
MALL Q13021 TMEM139 Homo sapiens Q8IV31
Validated Y2H
32296183
Intra
MALL Q13021 TMEM139 Homo sapiens Q8IV31
Y2H Prey Pooling
32296183
Intra
MALL Q13021 CLDN7 Homo sapiens O95471
Y2H Array
32296183
Intra
MALL Q13021 CLDN7 Homo sapiens O95471
Y2H Prey Pooling
32296183
Intra
MALL Q13021 KASH5 Homo sapiens Q8N6L0
Y2H Prey Pooling
25416956
Intra
MALL Q13021 KASH5 Homo sapiens Q8N6L0
Validated Y2H
25416956
Intra
MALL Q13021 BNIP3 Homo sapiens Q12983
Y2H Prey Pooling
32296183
Intra
MALL Q13021 BNIP3 Homo sapiens Q12983
Y2H Array
32296183
Intra
MALL Q13021 LEPROTL1 Homo sapiens O95214
Y2H Prey Pooling
32296183
Intra
MALL Q13021 LEPROTL1 Homo sapiens O95214
Y2H Array
32296183
Intra
MALL Q13021 CD79A Homo sapiens P11912
Y2H Prey Pooling
32296183
Intra
MALL Q13021 CD79A Homo sapiens P11912
Y2H Array
32296183
Intra
MALL Q13021 SYT2 Homo sapiens Q8N9I0
Y2H Prey Pooling
32296183
Intra
MALL Q13021 SYT2 Homo sapiens Q8N9I0
Validated Y2H
32296183
Intra
MALL Q13021 SYT2 Homo sapiens Q8N9I0
Y2H Array
32296183
Intra
MALL Q13021 IL7R Homo sapiens P16871
Y2H Array
32296183
Intra
MALL Q13021 IL7R Homo sapiens P16871
Y2H Prey Pooling
32296183
Intra
MALL Q13021 BNIP3L Homo sapiens O60238
Y2H Prey Pooling
32296183
Intra
MALL Q13021 BNIP3L Homo sapiens O60238
Y2H Array
32296183
Intra
MALL Q13021 KLRC1 Homo sapiens P26715
Y2H Array
32296183
Intra
MALL Q13021 KLRC1 Homo sapiens P26715
Y2H Prey Pooling
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Cascade Stomach

  • Hourglass Stricture Or Stenosis Of Stomach

  • Hourglass Contraction Of Stomach

  • Hourglass Stenosis Of Stomach

  • Hourglass Stricture Of Stomach
Joubert Syndrome 4

  • JBTS4

  • Joubert Syndrome With Renal Defect

  • Joubert Syndrome With Renal Anomalies

  • Js-R

  • Joubert Syndrome, Type 4
Nephronophthisis

  • Medullary Cystic Disease

  • Medullary Cystic Kidney

  • Nph

  • Nphp

  • Kidney Disease, Cystic, Medullary
Leukoencephalopathy With Vanishing White Matter

  • Cree Leukoencephalopathy

  • Vanishing White Matter Disease

  • Ovarioleukodystrophy

  • Vanishing White Matter Leukodystrophy

  • Childhood Ataxia With Central Nervous System Hypomyelinization

  • Cach

  • Cach Syndrome

  • Myelinosis Centralis Diffusa

  • VWM

  • Cle

  • Childhood Ataxia With Central Nervous System Hypomyelination

  • Childhood Ataxia With Diffuse Central Nervous System Hypomyelination

  • Cach/Vwm

  • Cach/Vwm Syndrome

  • Childhood Ataxia With Central Nervous System Hypomyelination/Vanishing White Matter

  • Cree Leukoencehalopathy

  • Late Infantile Cach Syndrome

  • Juvenile Or Adult Cach Syndrome

  • Congenital Or Early Infantile Cach Syndrome

  • Leukodystrophy With Vanishing White Matter
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07993 MALL Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17107 Mall Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23552 Mall Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus MALL VGNC VGNC:31154
Canis familiaris MALL VGNC VGNC:42934
Felis catus MALL VGNC VGNC:68141
Rattus norvegicus MALL RGD RGD:1310869
Mus musculus MALL MGD MGI:2385152
Others MALL NCBI