TMEM174 - transmembrane protein 174 Gene

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 134288

Summary

Predicted to be involved in phosphate ion homeostasis. Located in endoplasmic reticulum membrane. [provided by Alliance of Genome Resources, Jul 2025]
Restricted expression toward kidney (RPKM 66.3).

TMEM174 Products (1)

mRNA Protein Name
NM_153217.3 NP_694949.1 transmembrane protein 174

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
25416956 GOA
Cellular Component GO Annotation Evidence References Source
located in endoplasmic reticulum membrane IDA
IDA: Inferred from direct assay
20331980 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

TMEM174 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
TMEM174 Q8WUU8 KRT34 Homo sapiens O76011
Y2H Array
32296183
Intra
TMEM174 Q8WUU8 KRT34 Homo sapiens O76011
Y2H Prey Pooling
32296183
Intra
TMEM174 Q8WUU8 CMTM7 Homo sapiens Q96FZ5
Complementation
32296183
Intra
TMEM174 Q8WUU8 CMTM7 Homo sapiens Q96FZ5
Validated Y2H
32296183
Intra
TMEM174 Q8WUU8 SGTA Homo sapiens O43765
Validated Y2H
25416956
Intra
TMEM174 Q8WUU8 SGTA Homo sapiens O43765
Y2H Array
25416956
Intra
TMEM174 Q8WUU8 CYSRT1 Homo sapiens A8MQ03
Y2H Prey Pooling
32296183
Intra
TMEM174 Q8WUU8 CYSRT1 Homo sapiens A8MQ03
Y2H Array
32296183
Intra
TMEM174 Q8WUU8 PLLP Homo sapiens Q9Y342
Validated Y2H
32296183
Intra
TMEM174 Q8WUU8 SEC22A Homo sapiens Q96IW7
Validated Y2H
32296183
Intra
TMEM174 Q8WUU8 KRT31 Homo sapiens Q15323
Y2H Prey Pooling
32296183
Intra
TMEM174 Q8WUU8 KRT31 Homo sapiens Q15323
Y2H Array
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (24)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-162666 TMEM175 modulator 1 Modulator 98.91% Unkown
HY-RS29457 TMEM175 Monkey Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19555 Tmem175 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-181621 Tmem175 modulator 2 Modulator / Unkown
HY-181622 TMEM175 modulator 3 Activator / Unkown
HY-182768 TMEM175 modulator-4 Modulator / Unkown
HY-186253 TMEM175 agonist 1 Agonist / Unkown
HY-186254 TMEM175 agonist 2 Agonist / Unkown
HY-186257 TMEM175 agonist 3 Agonist / Unkown
HY-186258 TMEM175 agonist 4 Agonist / Unkown
HY-186259 TMEM175 agonist 5 Agonist / Unkown
HY-186260 TMEM175 agonist 6 Agonist / Unkown
HY-186261 TMEM175 agonist 7 Agonist / Unkown
HY-RS14670 TMEM147 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS14673 TMEM154 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS14678 TMEM164 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS14680 TMEM17 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS14682 TMEM171 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS14683 TMEM175 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS14686 TMEM177 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS14741 TMEM74 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20606 Tmem17 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26051 Tmem175 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27114 Tmem17 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown