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Cat. No.: HY-186260

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TMEM175 agonist 6

TMEM175 agonist 6 (Compound F-101) is a TMEM175 agonist. TMEM175 agonists can restore/enhance the function of lysosomes and reduce aSyn aggregation, thus being applicable for the research of diseases such as Parkinson's disease.

For research use only. We do not sell to patients.

CAS No.: 3132328-83-4
Formula: C₁₉H₁₂F₇N₃O₂
Molecular Weight:447.31

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

TMEM175 agonist 6 Chemical Structure

CAS No.: 3132328-83-4

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

Chemical Information

CAS No. 3132328-83-4
Molecular Weight 447.31
Formula C₁₉H₁₂F₇N₃O₂
SMILES

O=C1N(C=CC2=CC(C(F)(F)F)=CC=C21)[C@@H](C(NC3=C(N=C(C=C3)C(F)(F)F)F)=O)C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Oehlrich, et al. Preparation of N-phenyl-2-(1-oxoisoquinolin-2(1H)-yl)-propanamide derivatives as TMEM175 modulators for reducing alpha-synuclein aggregation for the treatment of Parkinson's disease. WO2026114612 A1.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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