TMEM175 agonist 1
TMEM175 agonist 1 is a TMEM175 agonist, with a human EC50 of 0.378 μM in FLIPR assays and a human EC50 of 0.886 μM in EP analyses. TMEM175 agonist 1 can be used in the research of Parkinson's disease, dementia with Lewy bodies, rapid eye movement sleep behavior disorder, amyotrophic lateral sclerosis, and lysosomal storage diseases.
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- CAS. Nr.: 3129653-69-3
- Formel: C27H26F3N5O5S
- Molecular Weight:589.59
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
TMEM175 agonist 1 (Compound 232) activates human TMEM175 in FLIPR assays, with an EC50 of 0.378 μM[1].
TMEM175 agonist 1 activates human TMEM175 in EP assays, with an EC50 value of 0.886 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 3129653-69-3
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Molecular Weight 589.59
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Formel C27H26F3N5O5S
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SMILES
CO[C@@H](C1=NC2=C(C(N1NS(=O)(C3=CC=C(C=C3)N[C@@H]4C[C@@H](C4)OC(F)F)=O)=O)C=CN=C2C)C5=CC=C(C=C5)F
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)