3129653-69-3
3129653-69-3
Chemical Structure
TMEM175 agonist 1
- CAS No.: 3129653-69-3
- Formula:C27H26F3N5O5S
- Molecular Weight:589.59
InChIKey: ICGVLRCORRESFB-JXALWOEJSA-N
SMILES: CO[C@@H](C1=NC2=C(C(N1NS(=O)(C3=CC=C(C=C3)N[C@@H]4C[C@@H](C4)OC(F)F)=O)=O)C=CN=C2C)C5=CC=C(C=C5)F
Biological Activity: TMEM175 agonist 1 is a TMEM175 agonist, with a human EC50 of 0.378 μM in FLIPR assays and a human EC50 of 0.886 μM in EP analyses. TMEM175 agonist 1 can be used in the research of Parkinson's disease, dementia with Lewy bodies, rapid eye movement sleep behavior disorder, amyotrophic lateral sclerosis, and lysosomal storage diseases[1].
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TMEM175 agonist 1 | TMEM175 agonist 1 is a TMEM175 agonist, with a human EC50 of 0.378 μM in FLIPR assays and a human EC50 of 0.886 μM in EP analyses. TMEM175 agonist 1 can be used in the research of Parkinson's disease, dementia with Lewy bodies, rapid eye movement sleep behavior disorder, amyotrophic lateral sclerosis, and lysosomal storage diseases. | |||||||||||||||||||||
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