TMEM175 agonist 5
TMEM175 agonist 5 (Compound 252) is a TMEM175 agonist with an EC50 of 421 nM in FLIPR cell assays. TMEM175 agonist 5 can be used for the research of neurodegenerative diseases and lysosomal storage disorders.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Formel: C20H18FN3O2
- Molecular Weight:351.37
-
Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biologische Aktivität
-
Chemical Information
- Reinheit & Dokumentation
- Verweise
-
Help & FAQs
Biologische Aktivität
|
TMEM175 421 nM (EC50) |
TMEM175 is a bifunctional channel protein on the lysosomal membrane with both proton and potassium ion permeability. It maintains lysosomal homeostasis and α-synuclein degradation, and its loss-of-function mutations significantly increase the risk of Parkinson's disease.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
Molecular Weight 351.37
-
Formel C20H18FN3O2
-
SMILES
O=C1C2=C(C=C(F)C=C2)N=CN1[C@H](C)C(NC3=CC=C(C4CC4)C=C3)=O
-
Versand
Room temperature in continental US; may vary elsewhere.
-
Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
TMEM175 agonist 5 Related Classifications
HY-186259 Related Classifications
Powered by Bioz