TMEM175 agonist 4
TMEM175 agonist 4 (Compound 276) is a TMEM175 agonist. TMEM175 agonist 4 can be used for the research of neurodegenerative diseases and lysosomal storage diseases.
For research use only. We do not sell to patients.
- Formula: C22H22F2N4O2
- Molecular Weight:412.43
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
|
TMEM175 138 nM (EC50) |
TMEM175 is a bifunctional channel protein located on the lysosomal membrane with permeability to both protons and potassium ions. It maintains lysosomal homeostasis and α-synuclein degradation, and its loss-of-function mutations significantly increase the risk of Parkinson's disease.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
Molecular Weight 412.43
-
Formula C22H22F2N4O2
-
SMILES
FC(C1=C2CCCC1)=CN(C(C)C(NC3=CC=C(C4=C(F)C=NN4C)C=C3)=O)C2=O
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)