NRIP3 - nuclear receptor interacting protein 3 Gene

Also Known as C11orf14; NY-SAR-105

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 56675

About NRIP3

Cytogenetic location: 11p15.4 Genomic coordinates (GRCh38): 11:8,980,576-9,004,505 (from NCBI)

This gene has 7 transcripts (splice variants), 168 orthologues and 4 paralogues. Biased expression in testis (RPKM 15.1), brain (RPKM 14.4) and 4 other tissues.

Summary

Predicted to enable aspartic-type endopeptidase activity. Predicted to be involved in proteolysis. [provided by Alliance of Genome Resources, Apr 2022]

NRIP3 Products (1)

mRNA Protein Name
NM_020645.3 NP_065696.1 nuclear receptor-interacting protein 3

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
25416956 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

NRIP3 Protein Structure

Asp_protease

Asp_protease: Aspartyl protease (105 - 209)

  • 0
  • 100
  • 200
  • 241 a.a.
Protein Preferred Names Protein Names

nuclear receptor-interacting protein 3

  • sarcoma antigen NY-SAR-105

NRIP3 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
NRIP3 Q9NQ35 C14orf119 Homo sapiens Q9NWQ9
Validated Y2H
32296183
Intra
NRIP3 Q9NQ35 KASH5 Homo sapiens Q8N6L0
Y2H Array
25416956
Intra
NRIP3 Q9NQ35 KASH5 Homo sapiens Q8N6L0
Y2H Array
32296183
Intra
NRIP3 Q9NQ35 KASH5 Homo sapiens Q8N6L0
Y2H Prey Pooling
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Arthrogryposis, Distal, Type 2a

  • Freeman-Sheldon Syndrome

  • Craniocarpotarsal Dystrophy

  • Craniocarpotarsal Dysplasia

  • DA2A

  • Whistling Face-Windmill Vane Hand Syndrome

  • Fss

  • Distal Arthrogryposis Type 2a

  • Whistling Face Syndrome

  • Freeman-Burian Syndrome

  • Arthrogryposis Distal Type 2a

  • Distal Arthrogryposis, Type 2a

  • Fbs

  • Arthrogryposis, Distal, 2a
Retinitis Pigmentosa 22

  • RP22

  • Retinitis Pigmentosa-22
Retinitis Pigmentosa 29

  • RP29
Nephronophthisis 11

  • NPHP11

  • Nephronophthisis, Type 11
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS09573 NRIP3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus NRIP3 VGNC VGNC:32264
Rattus norvegicus NRIP3 RGD RGD:1304777
Macaca mulatta NRIP3 VGNC VGNC:75397
Mus musculus NRIP3 MGD MGI:1925843
Felis catus NRIP3 VGNC VGNC:63880
Others NRIP3 NCBI