PPP1R18 - protein phosphatase 1 regulatory subunit 18 Gene

Also Known as HKMT1098; KIAA1949

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 170954

About PPP1R18

Cytogenetic location: 6p21.33 Genomic coordinates (GRCh38): 6:30,676,389-30,688,391 (from NCBI)

This gene has 6 transcripts (splice variants), 1 gene allele, 121 orthologues and 1 paralogue. Broad expression in lymph node (RPKM 31.8), appendix (RPKM 27.5) and 24 other tissues.

Summary

Protein phosphatase-1 (PP1; see MIM 176875) interacts with regulatory subunits that target the enzyme to different cellular locations and change its activity toward specific substrates. Phostensin is a regulatory subunit that targets PP1 to F-actin (see MIM 102610) Cytoskeleton (Kao et al., 2007 [PubMed 17374523]).[supplied by OMIM, Mar 2008]

PPP1R18 Products (2)

mRNA	Protein	Name
NM_001134870.2	NP_001128342.1	phostensin
NM_133471.4	NP_597728.1	phostensin

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	References	Source
enables protein binding	IPI IPI: Inferred from physical interaction	21516116	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

PPP1R18 Protein Structure

Phostensin_N

Phostensin

0
100
200
300
400
500
613 a.a.

Protein Preferred Names	Protein Names
phostensin	protein phosphatase 1 F-actin cytoskeleton targeting subunit

PPP1R18 Protein-protein interaction Information

Type	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	References
Intra	PPP1R18	Q6NYC8	CCDC136	Homo sapiens	Q96JN2-2	Validated Y2H	25416956
Intra	PPP1R18	Q6NYC8	KRT13	Homo sapiens	A1A4E9	Y2H Prey Pooling	25416956
Intra	PPP1R18	Q6NYC8	CCDC102B	Homo sapiens	Q68D86	Y2H Array	32296183
Intra	PPP1R18	Q6NYC8	CCDC102B	Homo sapiens	Q68D86	Y2H Prey Pooling	25416956
Intra	PPP1R18	Q6NYC8	CCDC102B	Homo sapiens	Q68D86	Y2H Prey Pooling	32296183
Intra	PPP1R18	Q6NYC8	CCDC102B	Homo sapiens	Q68D86	Validated Y2H	25416956
Intra	PPP1R18	Q6NYC8	KRT40	Homo sapiens	Q6A162	Y2H Prey Pooling	25416956
Intra	PPP1R18	Q6NYC8	KRT40	Homo sapiens	Q6A162	Y2H Array	25416956
Intra	PPP1R18	Q6NYC8	MID2	Homo sapiens	Q9UJV3-2	Y2H Array	32296183
Intra	PPP1R18	Q6NYC8	MID2	Homo sapiens	Q9UJV3-2	Y2H Prey Pooling	25416956
Intra	PPP1R18	Q6NYC8	MID2	Homo sapiens	Q9UJV3-2	Y2H Prey Pooling	32296183
Intra	PPP1R18	Q6NYC8	MID2	Homo sapiens	Q9UJV3-2	Validated Y2H	25416956
Intra	PPP1R18	Q6NYC8	MID2	Homo sapiens	Q9UJV3-2	Validated Y2H	32296183
Intra	PPP1R18	Q6NYC8	MID2	Homo sapiens	Q9UJV3-2	Y2H Array	25416956
Intra	PPP1R18	Q6NYC8	FAM9B	Homo sapiens	Q8IZU0	Validated Y2H	25416956
Intra	PPP1R18	Q6NYC8	FAM9B	Homo sapiens	Q8IZU0	Y2H Array	25416956
Intra	PPP1R18	Q6NYC8	KRT34	Homo sapiens	O76011	Y2H Prey Pooling	32296183
Intra	PPP1R18	Q6NYC8	KRT34	Homo sapiens	O76011	Y2H Array	32296183
Intra	PPP1R18	Q6NYC8	KRT33B	Homo sapiens	Q14525	Y2H Prey Pooling	32296183
Intra	PPP1R18	Q6NYC8	KRT33B	Homo sapiens	Q14525	Y2H Array	32296183
Intra	PPP1R18	Q6NYC8	DES	Homo sapiens	P17661	Validated Y2H	25416956
Intra	PPP1R18	Q6NYC8	DES	Homo sapiens	P17661	Y2H Array	32296183
Intra	PPP1R18	Q6NYC8	DES	Homo sapiens	P17661	Y2H Prey Pooling	32296183
Intra	PPP1R18	Q6NYC8	HOOK2	Homo sapiens	Q96ED9-2	Y2H Prey Pooling	32296183
Intra	PPP1R18	Q6NYC8	HOOK2	Homo sapiens	Q96ED9-2	Validated Y2H	32296183
Intra	PPP1R18	Q6NYC8	HOOK2	Homo sapiens	Q96ED9-2	Y2H Array	32296183
Intra	PPP1R18	Q6NYC8	PDE4DIP	Homo sapiens	Q5VU43	Y2H Prey Pooling	25416956
Intra	PPP1R18	Q6NYC8	PPP1R13B	Homo sapiens	Q96KQ4	Y2H Prey Pooling	32296183
Intra	PPP1R18	Q6NYC8	PPP1R13B	Homo sapiens	Q96KQ4	Validated Y2H	32296183
Intra	PPP1R18	Q6NYC8	PPP1R13B	Homo sapiens	Q96KQ4	Y2H Array	32296183
Intra	PPP1R18	Q6NYC8	TFIP11	Homo sapiens	Q9UBB9	Validated Y2H	25416956
Intra	PPP1R18	Q6NYC8	TFIP11	Homo sapiens	Q9UBB9	Y2H Array	25416956
Intra	PPP1R18	Q6NYC8	TFIP11	Homo sapiens	Q9UBB9	Y2H Prey Pooling	25416956
Intra	PPP1R18	Q6NYC8	CDR2L	Homo sapiens	Q86X02	Y2H Array	32296183
Intra	PPP1R18	Q6NYC8	CDR2L	Homo sapiens	Q86X02	Validated Y2H	32296183
Intra	PPP1R18	Q6NYC8	CDR2L	Homo sapiens	Q86X02	Y2H Prey Pooling	32296183
Intra	PPP1R18	Q6NYC8	GOPC	Homo sapiens	Q9HD26-2	Y2H Prey Pooling	32296183
Intra	PPP1R18	Q6NYC8	GOPC	Homo sapiens	Q9HD26-2	Validated Y2H	32296183
Intra	PPP1R18	Q6NYC8	GOPC	Homo sapiens	Q9HD26-2	Y2H Array	32296183
Intra	PPP1R18	Q6NYC8	MTUS2	Homo sapiens	Q5JR59-3	Y2H Prey Pooling	32296183
Intra	PPP1R18	Q6NYC8	MTUS2	Homo sapiens	Q5JR59-3	Y2H Array	32296183
Intra	PPP1R18	Q6NYC8	TEX11	Homo sapiens	Q8IYF3-3	Validated Y2H	32296183
Intra	PPP1R18	Q6NYC8	TEX11	Homo sapiens	Q8IYF3-3	Y2H Array	32296183
Intra	PPP1R18	Q6NYC8	TEX11	Homo sapiens	Q8IYF3-3	Y2H Prey Pooling	32296183
Intra	PPP1R18	Q6NYC8	CARD9	Homo sapiens	Q9H257-2	Validated Y2H	32296183
Intra	PPP1R18	Q6NYC8	CARD9	Homo sapiens	Q9H257-2	Y2H Prey Pooling	32296183
Intra	PPP1R18	Q6NYC8	CARD9	Homo sapiens	Q9H257-2	Y2H Array	32296183
Intra	PPP1R18	Q6NYC8	KRT36	Homo sapiens	O76013-2	Y2H Prey Pooling	32296183
Intra	PPP1R18	Q6NYC8	KRT36	Homo sapiens	O76013-2	Y2H Array	32296183
Intra	PPP1R18	Q6NYC8	BICD2	Homo sapiens	Q8TD16-2	Y2H Prey Pooling	32296183
Intra	PPP1R18	Q6NYC8	BICD2	Homo sapiens	Q8TD16-2	Y2H Array	32296183
Intra	PPP1R18	Q6NYC8	BICD2	Homo sapiens	Q8TD16-2	Validated Y2H	32296183
Intra	PPP1R18	Q6NYC8	ZMYND12	Homo sapiens	Q9H0C1	Y2H Array	32296183
Intra	PPP1R18	Q6NYC8	ZMYND12	Homo sapiens	Q9H0C1	Validated Y2H	32296183
Intra	PPP1R18	Q6NYC8	ZMYND12	Homo sapiens	Q9H0C1	Y2H Prey Pooling	32296183
Intra	PPP1R18	Q6NYC8	LZTS1	Homo sapiens	Q9Y250	Y2H Prey Pooling	32296183
Intra	PPP1R18	Q6NYC8	LZTS1	Homo sapiens	Q9Y250	Validated Y2H	32296183
Intra	PPP1R18	Q6NYC8	LZTS1	Homo sapiens	Q9Y250	Y2H Array	32296183
Intra	PPP1R18	Q6NYC8	TSC1	Homo sapiens	Q86WV8	Y2H Prey Pooling	32296183
Intra	PPP1R18	Q6NYC8	TSC1	Homo sapiens	Q86WV8	Validated Y2H	32296183
Intra	PPP1R18	Q6NYC8	TSC1	Homo sapiens	Q86WV8	Y2H Array	32296183
Intra	PPP1R18	Q6NYC8	PIBF1	Homo sapiens	Q4G0R1	Y2H Prey Pooling	32296183
Intra	PPP1R18	Q6NYC8	PIBF1	Homo sapiens	Q4G0R1	Y2H Array	32296183
Intra	PPP1R18	Q6NYC8	MEOX2	Homo sapiens	Q6FHY5	Y2H Array	32296183
Intra	PPP1R18	Q6NYC8	MEOX2	Homo sapiens	Q6FHY5	Y2H Prey Pooling	32296183
Intra	PPP1R18	Q6NYC8	TRIM54	Homo sapiens	Q9BYV2	Validated Y2H	25416956
Intra	PPP1R18	Q6NYC8	TRIM54	Homo sapiens	Q9BYV2	Validated Y2H	32296183
Intra	PPP1R18	Q6NYC8	TRIM54	Homo sapiens	Q9BYV2	Y2H Array	32296183
Intra	PPP1R18	Q6NYC8	TRIM54	Homo sapiens	Q9BYV2	Y2H Prey Pooling	25416956
Intra	PPP1R18	Q6NYC8	TRIM54	Homo sapiens	Q9BYV2	Y2H Prey Pooling	32296183
Intra	PPP1R18	Q6NYC8	GMCL1	Homo sapiens	Q96IK5	Y2H Prey Pooling	32296183
Intra	PPP1R18	Q6NYC8	GMCL1	Homo sapiens	Q96IK5	Validated Y2H	32296183
Intra	PPP1R18	Q6NYC8	GMCL1	Homo sapiens	Q96IK5	Y2H Array	32296183
Intra	PPP1R18	Q6NYC8	VPS52	Homo sapiens	Q8N1B4	Validated Y2H	32296183
Intra	PPP1R18	Q6NYC8	VPS52	Homo sapiens	Q8N1B4	Y2H Array	25416956
Intra	PPP1R18	Q6NYC8	VPS52	Homo sapiens	Q8N1B4	Y2H Array	32296183
Intra	PPP1R18	Q6NYC8	VPS52	Homo sapiens	Q8N1B4	Y2H Prey Pooling	32296183
Intra	PPP1R18	Q6NYC8	CCDC57	Homo sapiens	Q2TAC2	Validated Y2H	25416956
Intra	PPP1R18	Q6NYC8	CCDC57	Homo sapiens	Q2TAC2	Y2H Array	25416956
Intra	PPP1R18	Q6NYC8	ACTN3	Homo sapiens	Q08043	Y2H Array	32296183
Intra	PPP1R18	Q6NYC8	ACTN3	Homo sapiens	Q08043	Y2H Prey Pooling	32296183
Intra	PPP1R18	Q6NYC8	KRT27	Homo sapiens	Q7Z3Y8	Y2H Prey Pooling	32296183
Intra	PPP1R18	Q6NYC8	KRT27	Homo sapiens	Q7Z3Y8	Validated Y2H	32296183
Intra	PPP1R18	Q6NYC8	KRT27	Homo sapiens	Q7Z3Y8	Y2H Array	32296183
Intra	PPP1R18	Q6NYC8	CCDC88B	Homo sapiens	A6NC98	Y2H Prey Pooling	32296183
Intra	PPP1R18	Q6NYC8	CCDC88B	Homo sapiens	A6NC98	Y2H Array	32296183
Intra	PPP1R18	Q6NYC8	VIM	Homo sapiens	P08670	Y2H Prey Pooling	32296183
Intra	PPP1R18	Q6NYC8	VIM	Homo sapiens	P08670	Y2H Array	32296183
Intra	PPP1R18	Q6NYC8	TRAF2	Homo sapiens	Q12933	Y2H Array	25416956
Intra	PPP1R18	Q6NYC8	KRT16	Homo sapiens	P08779	Y2H Prey Pooling	32296183
Intra	PPP1R18	Q6NYC8	KRT16	Homo sapiens	P08779	Y2H Array	32296183
Intra	PPP1R18	Q6NYC8	PPP1CA	Homo sapiens	P62136	Y2H	22321011
Intra	PPP1R18	Q6NYC8	PPP1CA	Homo sapiens	P62136	Anti Tag CoIP	33961781
Intra	PPP1R18	Q6NYC8	EIF3L	Homo sapiens	Q9Y262	Y2H Array	32296183
Intra	PPP1R18	Q6NYC8	EIF3L	Homo sapiens	Q9Y262	Validated Y2H	32296183
Intra	PPP1R18	Q6NYC8	EIF3L	Homo sapiens	Q9Y262	Y2H Prey Pooling	32296183
Intra	PPP1R18	Q6NYC8	COG6	Homo sapiens	Q9Y2V7	Y2H Array	32296183
Intra	PPP1R18	Q6NYC8	COG6	Homo sapiens	Q9Y2V7	Y2H Prey Pooling	32296183
Intra	PPP1R18	Q6NYC8	COG6	Homo sapiens	Q9Y2V7	Validated Y2H	32296183
Intra	PPP1R18	Q6NYC8	ABRA	Homo sapiens	Q8N0Z2	Y2H Prey Pooling	32296183
Intra	PPP1R18	Q6NYC8	ABRA	Homo sapiens	Q8N0Z2	Validated Y2H	32296183
Intra	PPP1R18	Q6NYC8	ABRA	Homo sapiens	Q8N0Z2	Y2H Array	32296183
Intra	PPP1R18	Q6NYC8	KCTD9	Homo sapiens	Q7L273	Y2H Prey Pooling	25416956
Intra	PPP1R18	Q6NYC8	KCTD9	Homo sapiens	Q7L273	Y2H Array	25416956
Intra	PPP1R18	Q6NYC8	NEFL	Homo sapiens	P07196	Validated Y2H	25416956
Intra	PPP1R18	Q6NYC8	NEFL	Homo sapiens	P07196	Y2H Array	25416956
Intra	PPP1R18	Q6NYC8	ZRANB1	Homo sapiens	Q9UGI0	Validated Y2H	32296183
Intra	PPP1R18	Q6NYC8	ZRANB1	Homo sapiens	Q9UGI0	Y2H Prey Pooling	32296183
Intra	PPP1R18	Q6NYC8	ZRANB1	Homo sapiens	Q9UGI0	Y2H Array	32296183
Intra	PPP1R18	Q6NYC8	TCF4	Homo sapiens	P15884	Y2H Prey Pooling	25416956
Intra	PPP1R18	Q6NYC8	TCF4	Homo sapiens	P15884	Validated Y2H	25416956
Intra	PPP1R18	Q6NYC8	FSD2	Homo sapiens	A1L4K1	Y2H Prey Pooling	32296183
Intra	PPP1R18	Q6NYC8	FSD2	Homo sapiens	A1L4K1	Y2H Array	25416956
Intra	PPP1R18	Q6NYC8	FSD2	Homo sapiens	A1L4K1	Y2H Array	32296183
Intra	PPP1R18	Q6NYC8	GOLGA6L9	Homo sapiens	A6NEM1	Y2H Array	32296183
Intra	PPP1R18	Q6NYC8	GOLGA6L9	Homo sapiens	A6NEM1	Y2H Prey Pooling	32296183
Intra	PPP1R18	Q6NYC8	GOLGA2	Homo sapiens	Q08379	Y2H Array	32296183
Intra	PPP1R18	Q6NYC8	GOLGA2	Homo sapiens	Q08379	Validated Y2H	25416956
Intra	PPP1R18	Q6NYC8	GOLGA2	Homo sapiens	Q08379	Y2H Prey Pooling	25416956
Intra	PPP1R18	Q6NYC8	GOLGA2	Homo sapiens	Q08379	Y2H Prey Pooling	32296183
Intra	PPP1R18	Q6NYC8	GOLGA2	Homo sapiens	Q08379	Y2H Array	25416956
Intra	PPP1R18	Q6NYC8	TRIM62	Homo sapiens	Q9BVG3	Y2H Array	32296183
Intra	PPP1R18	Q6NYC8	TRIM62	Homo sapiens	Q9BVG3	Y2H Prey Pooling	32296183
Intra	PPP1R18	Q6NYC8	TRIM62	Homo sapiens	Q9BVG3	Validated Y2H	32296183
Intra	PPP1R18	Q6NYC8	HSF2BP	Homo sapiens	O75031	Y2H Prey Pooling	32296183
Intra	PPP1R18	Q6NYC8	HSF2BP	Homo sapiens	O75031	Y2H Array	32296183
Intra	PPP1R18	Q6NYC8	HAP1	Homo sapiens	P54257	Y2H Array	32296183
Intra	PPP1R18	Q6NYC8	HAP1	Homo sapiens	P54257	Y2H Prey Pooling	32296183
Intra	PPP1R18	Q6NYC8	STX11	Homo sapiens	O75558	Y2H Array	32296183
Intra	PPP1R18	Q6NYC8	STX11	Homo sapiens	O75558	Y2H Prey Pooling	25416956
Intra	PPP1R18	Q6NYC8	STX11	Homo sapiens	O75558	Y2H Prey Pooling	32296183
Intra	PPP1R18	Q6NYC8	SPDL1	Homo sapiens	Q96EA4	Y2H Prey Pooling	25416956
Intra	PPP1R18	Q6NYC8	GRIPAP1	Homo sapiens	Q4V328	MAPPIT	32296183
Intra	PPP1R18	Q6NYC8	GRIPAP1	Homo sapiens	Q4V328	Y2H Array	32296183
Intra	PPP1R18	Q6NYC8	GRIPAP1	Homo sapiens	Q4V328	Y2H Prey Pooling	32296183
Intra	PPP1R18	Q6NYC8	TRIM27	Homo sapiens	P14373	Y2H Prey Pooling	32296183
Intra	PPP1R18	Q6NYC8	TRIM27	Homo sapiens	P14373	Y2H Array	32296183
Intra	PPP1R18	Q6NYC8	TRIM27	Homo sapiens	P14373	Y2H Prey Pooling	25416956
Intra	PPP1R18	Q6NYC8	TRIM27	Homo sapiens	P14373	Validated Y2H	25416956
Intra	PPP1R18	Q6NYC8	TRIM27	Homo sapiens	P14373	Y2H	21516116
Intra	PPP1R18	Q6NYC8	MRPL38	Homo sapiens	Q96DV4	Validated Y2H	32296183
Intra	PPP1R18	Q6NYC8	MRPL38	Homo sapiens	Q96DV4	Y2H Prey Pooling	32296183
Intra	PPP1R18	Q6NYC8	MRPL38	Homo sapiens	Q96DV4	Y2H Array	32296183
Intra	PPP1R18	Q6NYC8	KRT15	Homo sapiens	P19012	Y2H Prey Pooling	25416956
Intra	PPP1R18	Q6NYC8	KRT15	Homo sapiens	P19012	Y2H Prey Pooling	32296183
Intra	PPP1R18	Q6NYC8	KRT15	Homo sapiens	P19012	Y2H Array	25416956
Intra	PPP1R18	Q6NYC8	KRT15	Homo sapiens	P19012	Y2H Array	32296183
Intra	PPP1R18	Q6NYC8	CALCOCO2	Homo sapiens	Q13137	Validated Y2H	25416956
Intra	PPP1R18	Q6NYC8	CEP70	Homo sapiens	Q8NHQ1	Y2H Array	32296183
Intra	PPP1R18	Q6NYC8	CEP70	Homo sapiens	Q8NHQ1	Y2H Prey Pooling	32296183
Intra	PPP1R18	Q6NYC8	CEP70	Homo sapiens	Q8NHQ1	Validated Y2H	32296183
Intra	PPP1R18	Q6NYC8	TRIM23	Homo sapiens	P36406	Y2H Prey Pooling	25416956
Intra	PPP1R18	Q6NYC8	GTPBP3	Homo sapiens	Q969Y2	Y2H Array	32296183
Intra	PPP1R18	Q6NYC8	GTPBP3	Homo sapiens	Q969Y2	Y2H Prey Pooling	32296183
Intra	PPP1R18	Q6NYC8	GTPBP3	Homo sapiens	Q969Y2	Validated Y2H	32296183
Intra	PPP1R18	Q6NYC8	LDOC1	Homo sapiens	O95751	Y2H Prey Pooling	32296183
Intra	PPP1R18	Q6NYC8	LDOC1	Homo sapiens	O95751	Y2H Array	32296183
Intra	PPP1R18	Q6NYC8	LZTS2	Homo sapiens	Q9BRK4	Y2H Prey Pooling	25416956
Intra	PPP1R18	Q6NYC8	LZTS2	Homo sapiens	Q9BRK4	Validated Y2H	25416956
Intra	PPP1R18	Q6NYC8	LZTS2	Homo sapiens	Q9BRK4	Y2H Array	25416956
Intra	PPP1R18	Q6NYC8	SORBS3	Homo sapiens	O60504	Y2H Prey Pooling	32296183
Intra	PPP1R18	Q6NYC8	SORBS3	Homo sapiens	O60504	Y2H Array	32296183
Intra	PPP1R18	Q6NYC8	PLEKHF2	Homo sapiens	Q9H8W4	Y2H Array	32296183
Intra	PPP1R18	Q6NYC8	PLEKHF2	Homo sapiens	Q9H8W4	Y2H Prey Pooling	32296183
Intra	PPP1R18	Q6NYC8	PLEKHF2	Homo sapiens	Q9H8W4	Validated Y2H	32296183
Intra	PPP1R18	Q6NYC8	TEX11	Homo sapiens	Q8IYF3	Y2H Array	25416956
Intra	PPP1R18	Q6NYC8	TEX11	Homo sapiens	Q8IYF3	Y2H Prey Pooling	25416956
Intra	PPP1R18	Q6NYC8	MAD1L1	Homo sapiens	Q9Y6D9	Y2H Prey Pooling	32296183
Intra	PPP1R18	Q6NYC8	MAD1L1	Homo sapiens	Q9Y6D9	Validated Y2H	32296183
Intra	PPP1R18	Q6NYC8	MAD1L1	Homo sapiens	Q9Y6D9	Y2H Array	32296183
Intra	PPP1R18	Q6NYC8	KRT19	Homo sapiens	P08727	Y2H Prey Pooling	25416956
Intra	PPP1R18	Q6NYC8	MTUS2	Homo sapiens	Q5JR59	Validated Y2H	25416956
Intra	PPP1R18	Q6NYC8	MTUS2	Homo sapiens	Q5JR59	Y2H Array	25416956
Intra	PPP1R18	Q6NYC8	GFAP	Homo sapiens	P14136	Y2H Prey Pooling	32296183
Intra	PPP1R18	Q6NYC8	GFAP	Homo sapiens	P14136	Y2H Array	32296183
Intra	PPP1R18	Q6NYC8	TSGA10	Homo sapiens	Q9BZW7	Validated Y2H	25416956
Intra	PPP1R18	Q6NYC8	TSGA10	Homo sapiens	Q9BZW7	Y2H Array	25416956
Intra	PPP1R18	Q6NYC8	GCC1	Homo sapiens	Q96CN9	Y2H Array	32296183
Intra	PPP1R18	Q6NYC8	GCC1	Homo sapiens	Q96CN9	Y2H Prey Pooling	32296183
Intra	PPP1R18	Q6NYC8	GCC1	Homo sapiens	Q96CN9	Validated Y2H	32296183
Intra	PPP1R18	Q6NYC8	IKZF3	Homo sapiens	Q9UKT9	Y2H Prey Pooling	32296183
Intra	PPP1R18	Q6NYC8	IKZF3	Homo sapiens	Q9UKT9	Validated Y2H	32296183
Intra	PPP1R18	Q6NYC8	IKZF3	Homo sapiens	Q9UKT9	Y2H Array	32296183
Intra	PPP1R18	Q6NYC8	HOMER3	Homo sapiens	Q9NSC5	Validated Y2H	25416956
Intra	PPP1R18	Q6NYC8	HOMER3	Homo sapiens	Q9NSC5	Validated Y2H	32296183
Intra	PPP1R18	Q6NYC8	HOMER3	Homo sapiens	Q9NSC5	Y2H Array	32296183
Intra	PPP1R18	Q6NYC8	HOMER3	Homo sapiens	Q9NSC5	Y2H Prey Pooling	32296183
Intra	PPP1R18	Q6NYC8	KASH5	Homo sapiens	Q8N6L0	Y2H Prey Pooling	32296183
Intra	PPP1R18	Q6NYC8	KASH5	Homo sapiens	Q8N6L0	Validated Y2H	32296183
Intra	PPP1R18	Q6NYC8	KASH5	Homo sapiens	Q8N6L0	Y2H Array	25416956
Intra	PPP1R18	Q6NYC8	KASH5	Homo sapiens	Q8N6L0	Y2H Array	32296183
Intra	PPP1R18	Q6NYC8	TRIM69	Homo sapiens	Q86WT6	Validated Y2H	25416956
Intra	PPP1R18	Q6NYC8	FHL5	Homo sapiens	Q5TD97	Y2H Prey Pooling	32296183
Intra	PPP1R18	Q6NYC8	FHL5	Homo sapiens	Q5TD97	Y2H Array	32296183
Intra	PPP1R18	Q6NYC8	CARD9	Homo sapiens	Q9H257	Y2H Array	25416956
Intra	PPP1R18	Q6NYC8	CARD9	Homo sapiens	Q9H257	Y2H Prey Pooling	25416956
Intra	PPP1R18	Q6NYC8	CARD9	Homo sapiens	Q9H257	Y2H Array	31515488
Intra	PPP1R18	Q6NYC8	PRPH	Homo sapiens	P41219	Y2H Prey Pooling	32296183
Intra	PPP1R18	Q6NYC8	PRPH	Homo sapiens	P41219	Y2H Array	32296183
Intra	PPP1R18	Q6NYC8	KRT31	Homo sapiens	Q15323	Y2H Array	32296183
Intra	PPP1R18	Q6NYC8	KRT31	Homo sapiens	Q15323	Y2H Prey Pooling	25416956
Intra	PPP1R18	Q6NYC8	KRT31	Homo sapiens	Q15323	Y2H Prey Pooling	32296183
Intra	PPP1R18	Q6NYC8	MAPK1	Homo sapiens	P28482	Y2H Prey Pooling	32296183
Intra	PPP1R18	Q6NYC8	MAPK1	Homo sapiens	P28482	Y2H Array	32296183
Intra	PPP1R18	Q6NYC8	DZIP1	Homo sapiens	Q86YF9	Y2H Prey Pooling	32296183
Intra	PPP1R18	Q6NYC8	DZIP1	Homo sapiens	Q86YF9	Validated Y2H	32296183
Intra	PPP1R18	Q6NYC8	DZIP1	Homo sapiens	Q86YF9	Y2H Array	32296183

Cross: Cross-species interaction Intra: Intraspecies interaction

PPP1R18 Antibodies

Cat. No.	Product Name	Application	Reactivity
HY-P81329	Phostensin Antibody (YA1074)	WB	Human
HY-P81329A	Phostensin Antibody (YA1074)(PBS only)	WB	Human
HY-P85576	Phostensin Antibody (YA5268)	WB	Human

Related Diseases

Diseases	Alias
Deafness, Autosomal Recessive 79	DFNB79 Autosomal Recessive Nonsyndromic Deafness 79 Autosomal Recessive Deafness 79 Deafness, Autosomal Recessive, 79 Non-Syndromic Neurosensory Deafness Autosomal Recessive Type 79 Deafness, Autosomal Recessive, Type 79
Schizophrenia 4	SCZD4 Schizophrenia, Susceptibility To, 4 Schizophrenia Susceptibility Locus, Chromosome 22q11-Related Schizophrenia Susceptibility Locus Chromosome 22-Related Schizophrenia, Type 4

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS10991	PPP1R18 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	PPP1R18	VGNC	VGNC:102489
Macaca mulatta	PPP1R18	VGNC	VGNC:104421
Bos taurus	PPP1R18	VGNC	VGNC:33233
Mus musculus	PPP1R18	MGD	MGI:1923698
Rattus norvegicus	PPP1R18	RGD	RGD:1309543
Canis familiaris	PPP1R18	VGNC	VGNC:57230
Others	PPP1R18	NCBI