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64978

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9

Inhibitors & Agonists

1

Recombinant Proteins

6

Antibodies

8

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-12558
    LY3009120
    10+ Cited Publications

    DP-4978

    		 Raf Autophagy Cancer
    LY3009120 (DP-4978) is a pan RAF inhibitor which inhibits BRAF V600E, BRAF WT and CRAF WT with IC50s of 5.8, 9.1 and 15 nM, respectively.
    LY3009120
  • HY-RI03687A
    mmu-miR-6978-5p antagomir

    		MicroRNA Cancer
    mmu-miR-6978-5p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
    mmu-miR-6978-5p antagomir
    mmu-miR-6978-5p antagomir
  • HY-R03686
    mmu-miR-6978-3p mimic

    		MicroRNA Cancer
    mmu-miR-6978-3p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.
    mmu-miR-6978-3p mimic
    mmu-miR-6978-3p mimic
  • HY-RI03687
    mmu-miR-6978-5p inhibitor

    		MicroRNA Cancer
    mmu-miR-6978-5p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.
    mmu-miR-6978-5p inhibitor
    mmu-miR-6978-5p inhibitor
  • HY-RI03686A
    mmu-miR-6978-3p antagomir

    		MicroRNA Cancer
    mmu-miR-6978-3p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
    mmu-miR-6978-3p antagomir
    mmu-miR-6978-3p antagomir
  • HY-R03687A
    mmu-miR-6978-5p agomir

    		MicroRNA Cancer
    mmu-miR-6978-5p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
    mmu-miR-6978-5p agomir
    mmu-miR-6978-5p agomir
  • HY-RI03686
    mmu-miR-6978-3p inhibitor

    		MicroRNA Cancer
    mmu-miR-6978-3p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.
    mmu-miR-6978-3p inhibitor
    mmu-miR-6978-3p inhibitor
  • HY-R03687
    mmu-miR-6978-5p mimic

    		MicroRNA Cancer
    mmu-miR-6978-5p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.
    mmu-miR-6978-5p mimic
    mmu-miR-6978-5p mimic
  • HY-R03686A
    mmu-miR-6978-3p agomir

    		MicroRNA Cancer
    mmu-miR-6978-3p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
    mmu-miR-6978-3p agomir
    mmu-miR-6978-3p agomir

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