GRIPAP1 - GRIP1 associated protein 1 Gene

Also Known as GRASP-1

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 56850

About GRIPAP1

Cytogenetic location: Xp11.23 Genomic coordinates (GRCh38): X:48,973,723-49,002,264 (from NCBI)

This gene has 107 transcripts (splice variants) and 191 orthologues. Ubiquitous expression in brain (RPKM 17.5), spleen (RPKM 12.2) and 25 other tissues.

Summary

This gene encodes a guanine nucleotide exchange factor for the Ras family of small G proteins (RasGEF). The encoded protein interacts in a complex with glutamate receptor interacting protein 1 (GRIP1) and plays a role in the regulation of AMPA Receptor function. [provided by RefSeq, Aug 2013]

GRIPAP1 Products (1)

mRNA Protein Name
NM_020137.5 NP_064522.4 GRIP1-associated protein 1

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables identical protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
21988832 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

GRIP1-associated protein 1

GRIPAP1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
GRIPAP1 Q4V328 CCDC103 Homo sapiens Q8IW40
Y2H Prey Pooling
32296183
Intra
GRIPAP1 Q4V328 CCDC103 Homo sapiens Q8IW40
Validated Y2H
32296183
Intra
GRIPAP1 Q4V328 CCDC103 Homo sapiens Q8IW40
Y2H Array
32296183
Intra
GRIPAP1 Q4V328 ATG5 Homo sapiens Q9H1Y0
Validated Y2H
32296183
Intra
GRIPAP1 Q4V328 GAS8 Homo sapiens O95995
Y2H Array
32296183
Intra
GRIPAP1 Q4V328 GAS8 Homo sapiens O95995
Y2H Prey Pooling
32296183
Intra
GRIPAP1 Q4V328 TSHZ2 Homo sapiens Q9NRE2
Validated Y2H
32296183
Intra
GRIPAP1 Q4V328 PKP2 Homo sapiens Q99959-2
Y2H Prey Pooling
32296183
Intra
GRIPAP1 Q4V328 PKP2 Homo sapiens Q99959-2
Validated Y2H
32296183
Intra
GRIPAP1 Q4V328 PKP2 Homo sapiens Q99959-2
Y2H Array
32296183
Intra
GRIPAP1 Q4V328 CEP57L1 Homo sapiens Q8IYX8
Y2H Prey Pooling
32296183
Intra
GRIPAP1 Q4V328 CEP57L1 Homo sapiens Q8IYX8
Validated Y2H
32296183
Intra
GRIPAP1 Q4V328 CEP57L1 Homo sapiens Q8IYX8
Y2H Array
32296183
Intra
GRIPAP1 Q4V328 TEPSIN Homo sapiens Q96N21
Validated Y2H
32296183
Intra
GRIPAP1 Q4V328 TEPSIN Homo sapiens Q96N21
Y2H Array
32296183
Intra
GRIPAP1 Q4V328 TEPSIN Homo sapiens Q96N21
Y2H Prey Pooling
32296183
Intra
GRIPAP1 Q4V328 NUAK2 Homo sapiens Q9H093
Validated Y2H
32296183
Intra
GRIPAP1 Q4V328 DISC1 Homo sapiens Q9NRI5-2
Y2H Prey Pooling
32296183
Intra
GRIPAP1 Q4V328 DISC1 Homo sapiens Q9NRI5-2
Validated Y2H
32296183
Intra
GRIPAP1 Q4V328 DISC1 Homo sapiens Q9NRI5-2
Y2H Array
32296183
Intra
GRIPAP1 Q4V328 SNAPC5 Homo sapiens O75971-2
Y2H Prey Pooling
32296183
Intra
GRIPAP1 Q4V328 SNAPC5 Homo sapiens O75971-2
Y2H Array
32296183
Intra
GRIPAP1 Q4V328 MGC50722 Homo sapiens Q8IVT4
Validated Y2H
32296183
Intra
GRIPAP1 Q4V328 RCOR3 Homo sapiens Q9P2K3-2
Validated Y2H
32296183
Intra
GRIPAP1 Q4V328 MEOX2 Homo sapiens Q6FHY5
Y2H Array
32296183
Intra
GRIPAP1 Q4V328 MEOX2 Homo sapiens Q6FHY5
Validated Y2H
32296183
Intra
GRIPAP1 Q4V328 MEOX2 Homo sapiens Q6FHY5
Y2H Prey Pooling
32296183
Intra
GRIPAP1 Q4V328 ANKRD11 Homo sapiens X5D778
Y2H Prey Pooling
32296183
Intra
GRIPAP1 Q4V328 ANKRD11 Homo sapiens X5D778
Validated Y2H
32296183
Intra
GRIPAP1 Q4V328 TBC1D30 Homo sapiens Q9Y2I9-2
Validated Y2H
32296183
Intra
GRIPAP1 Q4V328 TSNAX Homo sapiens Q99598
Y2H Prey Pooling
32296183
Intra
GRIPAP1 Q4V328 TSNAX Homo sapiens Q99598
Validated Y2H
32296183
Intra
GRIPAP1 Q4V328 TSNAX Homo sapiens Q99598
Y2H Array
32296183
Intra
GRIPAP1 Q4V328 PPP1R18 Homo sapiens Q6NYC8
Validated Y2H
32296183
Intra
GRIPAP1 Q4V328 ZMAT2 Homo sapiens Q96NC0
Validated Y2H
32296183
Intra
GRIPAP1 Q4V328 PRPF18 Homo sapiens Q99633
Validated Y2H
32296183
Intra
GRIPAP1 Q4V328 ING4 Homo sapiens Q9UNL4
Validated Y2H
32296183
Intra
GRIPAP1 Q4V328 DUSP26 Homo sapiens Q9BV47
Validated Y2H
32296183
Intra
GRIPAP1 Q4V328 TRAF2 Homo sapiens Q12933
Y2H Prey Pooling
32296183
Intra
GRIPAP1 Q4V328 TRAF2 Homo sapiens Q12933
Y2H Array
32296183
Intra
GRIPAP1 Q4V328 TCP10L Homo sapiens Q8TDR4
Validated Y2H
32296183
Intra
GRIPAP1 Q4V328 TCP10L Homo sapiens Q8TDR4
Y2H Prey Pooling
32296183
Intra
GRIPAP1 Q4V328 TCP10L Homo sapiens Q8TDR4
Y2H Array
32296183
Intra
GRIPAP1 Q4V328 ZNF219 Homo sapiens Q9P2Y4
Y2H Array
32296183
Intra
GRIPAP1 Q4V328 ZNF219 Homo sapiens Q9P2Y4
Y2H Prey Pooling
32296183
Intra
GRIPAP1 Q4V328 ZNF219 Homo sapiens Q9P2Y4
Validated Y2H
32296183
Intra
GRIPAP1 Q4V328 SMARCE1 Homo sapiens Q969G3
Validated Y2H
32296183
Intra
GRIPAP1 Q4V328 ING5 Homo sapiens Q8WYH8
Validated Y2H
32296183
Intra
GRIPAP1 Q4V328 ING5 Homo sapiens Q8WYH8
Y2H Array
32296183
Intra
GRIPAP1 Q4V328 ING5 Homo sapiens Q8WYH8
Y2H Prey Pooling
32296183
Intra
GRIPAP1 Q4V328 ZNF835 Homo sapiens Q9Y2P0
Validated Y2H
32296183
Intra
GRIPAP1 Q4V328 STAP1 Homo sapiens Q9ULZ2
Validated Y2H
32296183
Intra
GRIPAP1 Q4V328 SNW1 Homo sapiens Q13573
Y2H Prey Pooling
32296183
Intra
GRIPAP1 Q4V328 SNW1 Homo sapiens Q13573
Y2H Array
32296183
Intra
GRIPAP1 Q4V328 FAM90A1 Homo sapiens Q86YD7
Validated Y2H
32296183
Intra
GRIPAP1 Q4V328 CBX8 Homo sapiens Q9HC52
Validated Y2H
32296183
Intra
GRIPAP1 Q4V328 LNX1 Homo sapiens Q8TBB1
Validated Y2H
32296183
Intra
GRIPAP1 Q4V328 MLLT6 Homo sapiens P55198
Y2H Prey Pooling
32296183
Intra
GRIPAP1 Q4V328 MLLT6 Homo sapiens P55198
Y2H Array
32296183
Intra
GRIPAP1 Q4V328 CCDC185 Homo sapiens Q8N715
Validated Y2H
32296183
Intra
GRIPAP1 Q4V328 CFAP53 Homo sapiens Q96M91
Validated Y2H
32296183
Intra
GRIPAP1 Q4V328 FAM50B Homo sapiens Q9Y247
Validated Y2H
32296183
Intra
GRIPAP1 Q4V328 ENKD1 Homo sapiens Q9H0I2
Validated Y2H
32296183
Intra
GRIPAP1 Q4V328 DAXX Homo sapiens Q9UER7
Validated Y2H
32296183
Intra
GRIPAP1 Q4V328 TTC23 Homo sapiens Q5W5X9-3
Validated Y2H
32296183
Intra
GRIPAP1 Q4V328 TTC23 Homo sapiens Q5W5X9-3
Y2H Prey Pooling
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05811 GRIPAP1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris GRIPAP1 VGNC VGNC:41500
Rattus norvegicus GRIPAP1 RGD RGD:621249
Bos taurus GRIPAP1 VGNC VGNC:29653
Mus musculus GRIPAP1 MGD MGI:1859616
Macaca mulatta GRIPAP1 VGNC VGNC:73194
Felis catus GRIPAP1 VGNC VGNC:62716
Others GRIPAP1 NCBI