CBX8 - chromobox 8 Gene

Also Known as PC3; RC1

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 57332

About CBX8

Cytogenetic location: 17q25.3 Genomic coordinates (GRCh38): 17:79,792,132-79,797,077 (from NCBI)

This gene has 4 transcripts (splice variants), 271 orthologues and 8 paralogues. Ubiquitous expression in testis (RPKM 4.1), placenta (RPKM 2.1) and 25 other tissues.

Summary

Enables methylated histone binding activity. Involved in negative regulation of transcription by RNA polymerase II. Located in chromatin and nucleoplasm. Part of PRC1 complex. Biomarker of esophagus squamous cell carcinoma and glioblastoma. [provided by Alliance of Genome Resources, Apr 2022]

CBX8 Products (1)

mRNA Protein Name
NM_020649.3 NP_065700.1 chromobox protein homolog 8

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables methylated histone binding IDA
IDA: Inferred from direct assay
21029866 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
16169070 GOA
Biological Process GO Annotation Evidence References Source
involved in negative regulation of transcription by RNA polymerase II IMP
IMP: Inferred from mutant phenotype
19636380 GOA
Cellular Component GO Annotation Evidence References Source
part of PRC1 complex IDA
IDA: Inferred from direct assay
12167701 GOA
part of PcG protein complex IDA
IDA: Inferred from direct assay
21282530 GOA
located in chromatin IDA
IDA: Inferred from direct assay
19636380 GOA
located in nucleus IDA
IDA: Inferred from direct assay
21282530 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

CBX8 Protein Structure

Chromo

Chromo: Chromo (CHRromatin Organisation MOdifier) domain (13 - 60)

  • 0
  • 100
  • 200
  • 300
  • 389 a.a.
Protein Preferred Names Protein Names

chromobox protein homolog 8

  • Pc class 3 homolog

CBX8 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
CBX8 Q9HC52 CCDC136 Homo sapiens Q96JN2-2
Validated Y2H
25416956
Intra
CBX8 Q9HC52 CCDC136 Homo sapiens Q96JN2-2
Y2H Prey Pooling
25416956
Intra
CBX8 Q9HC52 KRT40 Homo sapiens Q6A162
Validated Y2H
25416956
Intra
CBX8 Q9HC52 KRT40 Homo sapiens Q6A162
Y2H Array
32296183
Intra
CBX8 Q9HC52 KRT40 Homo sapiens Q6A162
Y2H Prey Pooling
32296183
Intra
CBX8 Q9HC52 MID2 Homo sapiens Q9UJV3-2
Y2H Prey Pooling
32296183
Intra
CBX8 Q9HC52 MID2 Homo sapiens Q9UJV3-2
Validated Y2H
32296183
Intra
CBX8 Q9HC52 MID2 Homo sapiens Q9UJV3-2
Y2H Array
25416956
Intra
CBX8 Q9HC52 MID2 Homo sapiens Q9UJV3-2
Y2H Array
32296183
Intra
CBX8 Q9HC52 ZBTB14 Homo sapiens O43829
Y2H Array
32296183
Intra
CBX8 Q9HC52 ZBTB14 Homo sapiens O43829
Validated Y2H
25416956
Intra
CBX8 Q9HC52 ZBTB14 Homo sapiens O43829
Y2H Prey Pooling
32296183
Intra
CBX8 Q9HC52 PIH1D2 Homo sapiens Q8WWB5
Y2H Prey Pooling
32296183
Intra
CBX8 Q9HC52 PIH1D2 Homo sapiens Q8WWB5
Y2H Array
32296183
Intra
CBX8 Q9HC52 KRT34 Homo sapiens O76011
Y2H Array
32296183
Intra
CBX8 Q9HC52 KRT34 Homo sapiens O76011
Y2H Prey Pooling
32296183
Intra
CBX8 Q9HC52 PCGF6 Homo sapiens Q9BYE7
TAP
21282530
Intra
CBX8 Q9HC52 PCGF6 Homo sapiens Q9BYE7
TAP
27705803
Intra
CBX8 Q9HC52 PCGF6 Homo sapiens Q9BYE7
Pull Down
21282530
Intra
CBX8 Q9HC52 RPGRIP1 Homo sapiens Q96KN7
Y2H Prey Pooling
25416956
Intra
CBX8 Q9HC52 RPGRIP1 Homo sapiens Q96KN7
Y2H Array
25416956
Intra
CBX8 Q9HC52 RPGRIP1 Homo sapiens Q96KN7
Validated Y2H
25416956
Intra
CBX8 Q9HC52 POLR1C Homo sapiens O15160
Y2H Array
32296183
Intra
CBX8 Q9HC52 MOV10 Homo sapiens Q9HCE1
TAP
21282530
Intra
CBX8 Q9HC52 HOOK2 Homo sapiens Q96ED9-2
Y2H Array
32296183
Intra
CBX8 Q9HC52 HOOK2 Homo sapiens Q96ED9-2
Y2H Prey Pooling
32296183
Intra
CBX8 Q9HC52 FXR1 Homo sapiens P51114-2
Y2H Prey Pooling
32296183
Intra
CBX8 Q9HC52 FXR1 Homo sapiens P51114-2
Y2H Array
32296183
Intra
CBX8 Q9HC52 TFIP11 Homo sapiens Q9UBB9
Y2H Prey Pooling
32296183
Intra
CBX8 Q9HC52 TFIP11 Homo sapiens Q9UBB9
Validated Y2H
32296183
Intra
CBX8 Q9HC52 TFIP11 Homo sapiens Q9UBB9
Y2H Array
32296183
Intra
CBX8 Q9HC52 TEPSIN Homo sapiens Q96N21
Y2H Prey Pooling
32296183
Intra
CBX8 Q9HC52 TEPSIN Homo sapiens Q96N21
Y2H Array
32296183
Intra
CBX8 Q9HC52 PRDM6 Homo sapiens Q9NQX0
Y2H Prey Pooling
32296183
Intra
CBX8 Q9HC52 PRDM6 Homo sapiens Q9NQX0
Validated Y2H
32296183
Intra
CBX8 Q9HC52 PRDM6 Homo sapiens Q9NQX0
Y2H Array
32296183
Intra
CBX8 Q9HC52 MB21D2 Homo sapiens Q8IYB1
Y2H Array
32296183
Intra
CBX8 Q9HC52 MB21D2 Homo sapiens Q8IYB1
Y2H Prey Pooling
32296183
Intra
CBX8 Q9HC52 IKZF1 Homo sapiens Q13422-7
Y2H Prey Pooling
32296183
Intra
CBX8 Q9HC52 IKZF1 Homo sapiens Q13422-7
Y2H Array
32296183
Intra
CBX8 Q9HC52 MTUS2 Homo sapiens Q5JR59-3
Y2H Prey Pooling
32296183
Intra
CBX8 Q9HC52 MTUS2 Homo sapiens Q5JR59-3
Y2H Array
32296183
Intra
CBX8 Q9HC52 BANP Homo sapiens Q8N9N5-2
Y2H Array
32296183
Intra
CBX8 Q9HC52 BANP Homo sapiens Q8N9N5-2
Y2H Prey Pooling
32296183
Intra
CBX8 Q9HC52 CARD9 Homo sapiens Q9H257-2
Y2H Array
32296183
Intra
CBX8 Q9HC52 CARD9 Homo sapiens Q9H257-2
Y2H Prey Pooling
32296183
Intra
CBX8 Q9HC52 ABLIM3 Homo sapiens O94929-2
Y2H Array
32296183
Intra
CBX8 Q9HC52 ABLIM3 Homo sapiens O94929-2
Y2H Prey Pooling
32296183
Intra
CBX8 Q9HC52 JADE2 Homo sapiens A0A0C4DFT8
Y2H Prey Pooling
32296183
Intra
CBX8 Q9HC52 JADE2 Homo sapiens A0A0C4DFT8
Y2H Array
32296183
Intra
CBX8 Q9HC52 PIBF1 Homo sapiens Q4G0R1
Y2H Prey Pooling
32296183
Intra
CBX8 Q9HC52 PIBF1 Homo sapiens Q4G0R1
Y2H Array
32296183
Intra
CBX8 Q9HC52 KIFC3 Homo sapiens Q9BVG8-5
Y2H Prey Pooling
32296183
Intra
CBX8 Q9HC52 KIFC3 Homo sapiens Q9BVG8-5
Y2H Array
32296183
Intra
CBX8 Q9HC52 BACH2 Homo sapiens Q9BYV9
Y2H Array
32296183
Intra
CBX8 Q9HC52 BACH2 Homo sapiens Q9BYV9
Y2H Prey Pooling
32296183
Intra
CBX8 Q9HC52 KIFC3 Homo sapiens Q9BVG8
Y2H Array
25416956
Intra
CBX8 Q9HC52 PCGF2 Homo sapiens P35227
Anti Bait CoIP
19636380
Intra
CBX8 Q9HC52 PCGF2 Homo sapiens P35227
TAP
24981860
Intra
CBX8 Q9HC52 PCGF2 Homo sapiens P35227
TAP
21282530
Intra
CBX8 Q9HC52 PCGF2 Homo sapiens P35227
TAP
27705803
Intra
CBX8 Q9HC52 TRIM54 Homo sapiens Q9BYV2
Y2H Prey Pooling
32296183
Intra
CBX8 Q9HC52 TRIM54 Homo sapiens Q9BYV2
Y2H Array
32296183
Intra
CBX8 Q9HC52 PCGF3 Homo sapiens Q3KNV8
Anti Tag CoIP
21282530
Intra
CBX8 Q9HC52 PCGF3 Homo sapiens Q3KNV8
TAP
21282530
Intra
CBX8 Q9HC52 PCGF3 Homo sapiens Q3KNV8
TAP
27705803
Intra
CBX8 Q9HC52 BMI1 Homo sapiens P35226
TAP
21282530
Intra
CBX8 Q9HC52 BMI1 Homo sapiens P35226
Pull Down
21282530
Intra
CBX8 Q9HC52 BMI1 Homo sapiens P35226
Anti Bait CoIP
19636380
Intra
CBX8 Q9HC52 BMI1 Homo sapiens P35226
Anti Bait CoIP
17332741
Intra
CBX8 Q9HC52 BMI1 Homo sapiens P35226
Anti Bait CoIP
20601937
Intra
CBX8 Q9HC52 BMI1 Homo sapiens P35226
TAP
24981860
Intra
CBX8 Q9HC52 HMBOX1 Homo sapiens Q6NT76
Y2H Array
32296183
Intra
CBX8 Q9HC52 HMBOX1 Homo sapiens Q6NT76
Y2H Prey Pooling
25416956
Intra
CBX8 Q9HC52 HMBOX1 Homo sapiens Q6NT76
Y2H Prey Pooling
32296183
Intra
CBX8 Q9HC52 HMBOX1 Homo sapiens Q6NT76
Validated Y2H
25416956
Intra
CBX8 Q9HC52 HMBOX1 Homo sapiens Q6NT76
Y2H Array
25416956
Intra
CBX8 Q9HC52 KANK2 Homo sapiens Q63ZY3
Y2H Prey Pooling
32296183
Intra
CBX8 Q9HC52 KANK2 Homo sapiens Q63ZY3
Y2H Array
32296183
Intra
CBX8 Q9HC52 JAKMIP1 Homo sapiens Q96N16
Y2H Prey Pooling
32296183
Intra
CBX8 Q9HC52 JAKMIP1 Homo sapiens Q96N16
Y2H Array
32296183
Intra
CBX8 Q9HC52 PRKAR1B Homo sapiens P31321
Y2H Array
32296183
Intra
CBX8 Q9HC52 PRKAR1B Homo sapiens P31321
Y2H Prey Pooling
32296183
Intra
CBX8 Q9HC52 CCDC57 Homo sapiens Q2TAC2
Y2H Prey Pooling
25416956
Intra
CBX8 Q9HC52 PCGF5 Homo sapiens Q86SE9
Anti Tag CoIP
26496610
Intra
CBX8 Q9HC52 PCGF5 Homo sapiens Q86SE9
TAP
21282530
Intra
CBX8 Q9HC52 PCGF5 Homo sapiens Q86SE9
TAP
27705803
Intra
CBX8 Q9HC52 RASSF3 Homo sapiens Q86WH2
Y2H Prey Pooling
32296183
Intra
CBX8 Q9HC52 RASSF3 Homo sapiens Q86WH2
Y2H Array
32296183
Intra
CBX8 Q9HC52 PNMA1 Homo sapiens Q8ND90
Y2H Prey Pooling
32296183
Intra
CBX8 Q9HC52 PNMA1 Homo sapiens Q8ND90
Y2H Array
32296183
Intra
CBX8 Q9HC52 PNMA2 Homo sapiens Q9UL42
Y2H Prey Pooling
32296183
Intra
CBX8 Q9HC52 PNMA2 Homo sapiens Q9UL42
Validated Y2H
25416956
Intra
CBX8 Q9HC52 PNMA2 Homo sapiens Q9UL42
Validated Y2H
32296183
Intra
CBX8 Q9HC52 PNMA2 Homo sapiens Q9UL42
Y2H Array
32296183
Intra
CBX8 Q9HC52 USP7 Homo sapiens Q93009
Anti Tag CoIP
20601937
Intra
CBX8 Q9HC52 USP7 Homo sapiens Q93009
Anti Bait CoIP
20601937
Intra
CBX8 Q9HC52 USP7 Homo sapiens Q93009
Pull Down
20601937
Intra
CBX8 Q9HC52 USP11 Homo sapiens P51784
Anti Tag CoIP
20601937
Intra
CBX8 Q9HC52 USP11 Homo sapiens P51784
Anti Bait CoIP
20601937
Intra
CBX8 Q9HC52 MCC Homo sapiens P23508
Y2H Prey Pooling
32296183
Intra
CBX8 Q9HC52 MCC Homo sapiens P23508
Y2H Array
32296183
Intra
CBX8 Q9HC52 LSM2 Homo sapiens Q9Y333
Y2H Array
32296183
Intra
CBX8 Q9HC52 LSM2 Homo sapiens Q9Y333
Y2H Prey Pooling
32296183
Intra
CBX8 Q9HC52 LSM2 Homo sapiens Q9Y333
Validated Y2H
32296183
Intra
CBX8 Q9HC52 SOX5 Homo sapiens P35711
Y2H Prey Pooling
25416956
Intra
CBX8 Q9HC52 VIM Homo sapiens P08670
Y2H Prey Pooling
32296183
Intra
CBX8 Q9HC52 VIM Homo sapiens P08670
Y2H Array
32296183
Intra
CBX8 Q9HC52 TRAF2 Homo sapiens Q12933
Y2H Prey Pooling
25416956
Intra
CBX8 Q9HC52 TRAF2 Homo sapiens Q12933
Y2H Prey Pooling
32296183
Intra
CBX8 Q9HC52 TRAF2 Homo sapiens Q12933
Y2H Array
32296183
Intra
CBX8 Q9HC52 CARD10 Homo sapiens Q9BWT7
Y2H Prey Pooling
32296183
Intra
CBX8 Q9HC52 CARD10 Homo sapiens Q9BWT7
Y2H Array
32296183
Intra
CBX8 Q9HC52 ZBTB9 Homo sapiens Q96C00
Y2H Prey Pooling
32296183
Intra
CBX8 Q9HC52 ZBTB9 Homo sapiens Q96C00
Y2H Array
32296183
Intra
CBX8 Q9HC52 KAT5 Homo sapiens Q92993
Y2H Pooling
16169070
Intra
CBX8 Q9HC52 KAT5 Homo sapiens Q92993
Anti Tag CoIP
22094252
Intra
CBX8 Q9HC52 KCTD9 Homo sapiens Q7L273
Y2H Array
32296183
Intra
CBX8 Q9HC52 KCTD9 Homo sapiens Q7L273
Y2H Prey Pooling
32296183
Intra
CBX8 Q9HC52 KCTD9 Homo sapiens Q7L273
Validated Y2H
25416956
Intra
CBX8 Q9HC52 GPRASP2 Homo sapiens Q96D09
Y2H Array
32296183
Intra
CBX8 Q9HC52 GPRASP2 Homo sapiens Q96D09
Y2H Prey Pooling
25416956
Intra
CBX8 Q9HC52 GPRASP2 Homo sapiens Q96D09
Y2H Array
25416956
Intra
CBX8 Q9HC52 GPRASP2 Homo sapiens Q96D09
Y2H Prey Pooling
32296183
Intra
CBX8 Q9HC52 TRIB3 Homo sapiens Q96RU7
Y2H Prey Pooling
32296183
Intra
CBX8 Q9HC52 TRIB3 Homo sapiens Q96RU7
Y2H Array
32296183
Intra
CBX8 Q9HC52 ZRANB1 Homo sapiens Q9UGI0
Y2H Prey Pooling
32296183
Intra
CBX8 Q9HC52 ZRANB1 Homo sapiens Q9UGI0
Validated Y2H
32296183
Intra
CBX8 Q9HC52 ZRANB1 Homo sapiens Q9UGI0
Y2H Array
32296183
Intra
CBX8 Q9HC52 TAX1BP1 Homo sapiens Q86VP1
Y2H Array
32296183
Intra
CBX8 Q9HC52 TAX1BP1 Homo sapiens Q86VP1
Y2H Prey Pooling
32296183
Intra
CBX8 Q9HC52 H1-5 Homo sapiens P16401
Crosslink
30021884
Intra
CBX8 Q9HC52 H1-5 Homo sapiens P16401
Anti Tag CoIP
26496610
Intra
CBX8 Q9HC52 FSD2 Homo sapiens A1L4K1
Y2H Array
32296183
Intra
CBX8 Q9HC52 FSD2 Homo sapiens A1L4K1
Validated Y2H
25416956
Intra
CBX8 Q9HC52 FSD2 Homo sapiens A1L4K1
Y2H Prey Pooling
32296183
Intra
CBX8 Q9HC52 GOLGA6L9 Homo sapiens A6NEM1
Y2H Array
32296183
Intra
CBX8 Q9HC52 GOLGA6L9 Homo sapiens A6NEM1
Y2H Prey Pooling
32296183
Intra
CBX8 Q9HC52 SESTD1 Homo sapiens Q86VW0
Y2H Prey Pooling
32296183
Intra
CBX8 Q9HC52 SESTD1 Homo sapiens Q86VW0
Y2H Array
32296183
Intra
CBX8 Q9HC52 GOLGA2 Homo sapiens Q08379
Y2H Array
32296183
Intra
CBX8 Q9HC52 GOLGA2 Homo sapiens Q08379
Y2H Prey Pooling
32296183
Intra
CBX8 Q9HC52 ZNF185 Homo sapiens O15231
Y2H Prey Pooling
32296183
Intra
CBX8 Q9HC52 ZNF185 Homo sapiens O15231
Y2H Array
32296183
Intra
CBX8 Q9HC52 HSF2BP Homo sapiens O75031
Y2H Array
32296183
Intra
CBX8 Q9HC52 HSF2BP Homo sapiens O75031
Y2H Prey Pooling
32296183
Intra
CBX8 Q9HC52 PHC2 Homo sapiens Q8IXK0
Validated Y2H
25416956
Intra
CBX8 Q9HC52 PHC2 Homo sapiens Q8IXK0
Y2H Array
25416956
Intra
CBX8 Q9HC52 PHC2 Homo sapiens Q8IXK0
Anti Bait CoIP
19636380
Intra
CBX8 Q9HC52 PHC2 Homo sapiens Q8IXK0
Imaging
17332741
Intra
CBX8 Q9HC52 PHC2 Homo sapiens Q8IXK0
TAP
27705803
Intra
CBX8 Q9HC52 PHC2 Homo sapiens Q8IXK0
TAP
24981860
Intra
CBX8 Q9HC52 TFCP2 Homo sapiens Q12800
Y2H Prey Pooling
25416956
Intra
CBX8 Q9HC52 TFCP2 Homo sapiens Q12800
Y2H Prey Pooling
32296183
Intra
CBX8 Q9HC52 TFCP2 Homo sapiens Q12800
Y2H Array
32296183
Intra
CBX8 Q9HC52 GRIPAP1 Homo sapiens Q4V328
Y2H Array
32296183
Intra
CBX8 Q9HC52 GRIPAP1 Homo sapiens Q4V328
Y2H Prey Pooling
32296183
Intra
CBX8 Q9HC52 TRIM27 Homo sapiens P14373
Y2H Array
32296183
Intra
CBX8 Q9HC52 TRIM27 Homo sapiens P14373
Y2H Prey Pooling
32296183
Intra
CBX8 Q9HC52 RNF2 Homo sapiens Q99496
Anti Bait CoIP
19636380
Intra
CBX8 Q9HC52 RNF2 Homo sapiens Q99496
Anti Tag CoIP
26496610
Intra
CBX8 Q9HC52 RNF2 Homo sapiens Q99496
Anti Tag CoIP
21282530
Intra
CBX8 Q9HC52 RNF2 Homo sapiens Q99496
TAP
21282530
Intra
CBX8 Q9HC52 RNF2 Homo sapiens Q99496
TAP
24981860
Intra
CBX8 Q9HC52 RNF2 Homo sapiens Q99496
TAP
27705803
Intra
CBX8 Q9HC52 CBX4 Homo sapiens O00257
TAP
24981860
Intra
CBX8 Q9HC52 CBX4 Homo sapiens O00257
Anti Tag CoIP
26496610
Intra
CBX8 Q9HC52 MDFI Homo sapiens Q99750
Y2H Prey Pooling
32296183
Intra
CBX8 Q9HC52 MDFI Homo sapiens Q99750
Y2H Array
32296183
Intra
CBX8 Q9HC52 TSC22D4 Homo sapiens Q9Y3Q8
Y2H Prey Pooling
32296183
Intra
CBX8 Q9HC52 TSC22D4 Homo sapiens Q9Y3Q8
Validated Y2H
32296183
Intra
CBX8 Q9HC52 TSC22D4 Homo sapiens Q9Y3Q8
Y2H Array
32296183
Intra
CBX8 Q9HC52 CALCOCO2 Homo sapiens Q13137
Y2H Array
32296183
Intra
CBX8 Q9HC52 CALCOCO2 Homo sapiens Q13137
Y2H Prey Pooling
25416956
Intra
CBX8 Q9HC52 CALCOCO2 Homo sapiens Q13137
Y2H Prey Pooling
32296183
Intra
CBX8 Q9HC52 CEP70 Homo sapiens Q8NHQ1
Y2H Prey Pooling
32296183
Intra
CBX8 Q9HC52 CEP70 Homo sapiens Q8NHQ1
Y2H Array
32296183
Intra
CBX8 Q9HC52 DVL3 Homo sapiens Q92997
Y2H Array
32296183
Intra
CBX8 Q9HC52 DVL3 Homo sapiens Q92997
Y2H Prey Pooling
32296183
Intra
CBX8 Q9HC52 TRIM23 Homo sapiens P36406
Y2H Prey Pooling
32296183
Intra
CBX8 Q9HC52 TRIM23 Homo sapiens P36406
Y2H Array
32296183
Intra
CBX8 Q9HC52 LZTS2 Homo sapiens Q9BRK4
Y2H Prey Pooling
32296183
Intra
CBX8 Q9HC52 LZTS2 Homo sapiens Q9BRK4
Y2H Array
25416956
Intra
CBX8 Q9HC52 LZTS2 Homo sapiens Q9BRK4
Y2H Array
32296183
Intra
CBX8 Q9HC52 FHL3 Homo sapiens Q13643
Y2H Prey Pooling
32296183
Intra
CBX8 Q9HC52 FHL3 Homo sapiens Q13643
Y2H Array
32296183
Intra
CBX8 Q9HC52 PLEKHF2 Homo sapiens Q9H8W4
Y2H Prey Pooling
32296183
Intra
CBX8 Q9HC52 PLEKHF2 Homo sapiens Q9H8W4
Y2H Array
32296183
Intra
CBX8 Q9HC52 ZBTB8A Homo sapiens Q96BR9
Y2H Prey Pooling
32296183
Intra
CBX8 Q9HC52 ZBTB8A Homo sapiens Q96BR9
Y2H Array
32296183
Intra
CBX8 Q9HC52 MTUS2 Homo sapiens Q5JR59
Y2H Array
25416956
Intra
CBX8 Q9HC52 MTUS2 Homo sapiens Q5JR59
Y2H Prey Pooling
25416956
Intra
CBX8 Q9HC52 TSGA10 Homo sapiens Q9BZW7
Y2H Prey Pooling
25416956
Intra
CBX8 Q9HC52 IKZF1 Homo sapiens Q13422
Validated Y2H
25416956
Intra
CBX8 Q9HC52 IKZF1 Homo sapiens Q13422
Y2H Array
25416956
Intra
CBX8 Q9HC52 IKZF1 Homo sapiens Q13422
Y2H Prey Pooling
25416956
Intra
CBX8 Q9HC52 PCGF1 Homo sapiens Q9BSM1
TAP
27705803
Intra
CBX8 Q9HC52 PCGF1 Homo sapiens Q9BSM1
TAP
21282530
Intra
CBX8 Q9HC52 PCGF1 Homo sapiens Q9BSM1
Pull Down
21282530
Intra
CBX8 Q9HC52 PCGF1 Homo sapiens Q9BSM1
Anti Tag CoIP
27505670
Intra
CBX8 Q9HC52 RING1 Homo sapiens Q06587
TAP
27705803
Intra
CBX8 Q9HC52 RING1 Homo sapiens Q06587
Validated Y2H
25416956
Intra
CBX8 Q9HC52 RING1 Homo sapiens Q06587
Anti Tag CoIP
26496610
Intra
CBX8 Q9HC52 RING1 Homo sapiens Q06587
TAP
21282530
Intra
CBX8 Q9HC52 RING1 Homo sapiens Q06587
Y2H Array
25416956
Intra
CBX8 Q9HC52 RING1 Homo sapiens Q06587
Y2H Array
32296183
Intra
CBX8 Q9HC52 RING1 Homo sapiens Q06587
Y2H Prey Pooling
32296183
Intra
CBX8 Q9HC52 PICK1 Homo sapiens Q9NRD5
Y2H Prey Pooling
32296183
Intra
CBX8 Q9HC52 PICK1 Homo sapiens Q9NRD5
Validated Y2H
32296183
Intra
CBX8 Q9HC52 PICK1 Homo sapiens Q9NRD5
Y2H Array
32296183
Intra
CBX8 Q9HC52 PHACTR1 Homo sapiens Q9C0D0
Y2H Prey Pooling
32296183
Intra
CBX8 Q9HC52 PHACTR1 Homo sapiens Q9C0D0
Y2H Array
32296183
Intra
CBX8 Q9HC52 USH1G Homo sapiens Q495M9
Y2H Array
32296183
Intra
CBX8 Q9HC52 USH1G Homo sapiens Q495M9
Y2H Prey Pooling
32296183
Intra
CBX8 Q9HC52 NAB2 Homo sapiens Q15742
Y2H Array
32296183
Intra
CBX8 Q9HC52 NAB2 Homo sapiens Q15742
Y2H Prey Pooling
32296183
Intra
CBX8 Q9HC52 TTC23 Homo sapiens Q5W5X9-3
Y2H Array
32296183
Intra
CBX8 Q9HC52 TTC23 Homo sapiens Q5W5X9-3
Y2H Prey Pooling
32296183
Intra
CBX8 Q9HC52 GIGYF1 Homo sapiens O75420
Y2H Prey Pooling
32296183
Intra
CBX8 Q9HC52 GIGYF1 Homo sapiens O75420
Y2H Array
32296183
Intra
CBX8 Q9HC52 KRT31 Homo sapiens Q15323
Y2H Array
32296183
Intra
CBX8 Q9HC52 KRT31 Homo sapiens Q15323
Y2H Prey Pooling
32296183
Intra
CBX8 Q9HC52 BCOR Homo sapiens Q6W2J9
Anti Bait CoIP
27505670
Intra
CBX8 Q9HC52 BCOR Homo sapiens Q6W2J9
TAP
27705803
Intra
CBX8 Q9HC52 BCOR Homo sapiens Q6W2J9
Anti Tag CoIP
27505670
Cross: Cross-species interaction Intra: Intraspecies interaction

CBX8 Antibodies

Cat. No. Product Name Application Reactivity
HY-P84807 CBX8 Antibody (YA4504) WB, FC, ELISA Human
HY-P84807A CBX8 Antibody (YA4504)(PBS only) WB, FC, ELISA Human

Related Diseases

Diseases Alias
Retinitis Pigmentosa 7

  • Leber Congenital Amaurosis 18

  • RP7

  • Retinitis Pigmentosa 7, Digenic Form

  • Retinitis Pigmentosa 7 And Digenic Form

  • Retinitis Pigmentosa 7, Digenic

  • LCA18

  • Retinitis Pigmentosa 7 Digenic
Glioblastoma

  • Glioblastoma Multiforme

  • Gbm

  • Adult Glioblastoma Multiforme

  • Grade Iv Adult Astrocytic Tumor

  • Primary Glioblastoma Multiforme

  • Spongioblastoma Multiforme

  • Adult Glioblastoma

  • Primary Glioblastoma
Retinitis Pigmentosa 90

  • RP90

  • Retinitis Pigmentosa, Type 90
Root Caries

  • Cementum Caries

  • Dental Caries Of Root Surface
Conversion Disorder

  • Conversion Hysteria Or Reaction

  • Conversion Hysterical Neurosis

  • Hysterical Neurosis, Conversion Type

  • Fnd

  • Functional Movement Disorder

  • Functional Neurological Disorder

  • Dissociative Disorder
Esophagus Squamous Cell Carcinoma

  • Esophageal Squamous Cell Carcinoma

  • Oesophagus Squamous Cell Carcinoma

  • Scc Of Esophagus

  • Scc Of Oesophagus

  • Squamous Cell Carcinoma Of The Esophagus

  • Escc

  • Esophageal Epidermoid Carcinoma

  • Squamous Cell Esophageal Cancer

  • Squamous Cell Carcinoma Of Esophagus
Hypochondriasis

  • Hypochondriacal Disorder

  • Hypochondria

  • Hypochondriacal Neurosis

  • Illness Anxiety Disorder

  • Health Anxiety Disorder

  • Hypochondriacal Reaction
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-141716 SW2_110A Inhibitor 99.19% Unkown
HY-181089 CBX2-IN-1 Inhibitor / Unkown
HY-RS02015 CBX8 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19122 Cbx8 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25612 Cbx8 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus CBX8 MGD MGI:1353589
Bos taurus CBX8 VGNC VGNC:26821
Rattus norvegicus CBX8 RGD RGD:1565375
Canis familiaris CBX8 VGNC VGNC:38769
Macaca mulatta CBX8 VGNC VGNC:99128
Felis catus CBX8 VGNC VGNC:60426
Others CBX8 NCBI