PIH1D2 - PIH1 domain containing 2 Gene
Also Known as DNAAF15
Species: Homo sapiens
Gene Type: protein coding
Gene ID: 120379
Summary
Enables small GTPase binding activity. Predicted to be involved in box C/D snoRNP assembly and rRNA processing. Predicted to be part of R2TP complex and ribonucleoprotein complex. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Jun 2026]
Broad expression in testis (RPKM 17.4), heart (RPKM 9.8) and 20 other tissues.
PIH1D2 Products (5)
| mRNA | Protein | Name |
|---|---|---|
| NM_001082619.2 | NP_001076088.1 | PIH1 domain-containing protein 2 isoform 2 |
| NM_001439210.1 | NP_001426139.1 | PIH1 domain-containing protein 2 isoform 3 |
| NM_001439211.1 | NP_001426140.1 | PIH1 domain-containing protein 2 isoform 1 |
| NM_001439212.1 | NP_001426141.1 | PIH1 domain-containing protein 2 isoform 2 |
| NM_138789.4 | NP_620144.1 | PIH1 domain-containing protein 2 isoform 1 |
| Molecular Function GO Annotation | Evidence | References | Source |
|---|---|---|---|
| enables protein binding |
IPI
IPI: Inferred from physical interaction
|
25416956 | GOA |
| enables small GTPase binding |
IPI
IPI: Inferred from physical interaction
|
24056301 | GOA |
| Cellular Component GO Annotation | Evidence | References | Source |
|---|---|---|---|
| part of protein folding chaperone complex |
IPI
IPI: Inferred from physical interaction
|
29844425 | GOA |
EXP: Inferred from Experiment
IDA: Inferred from direct assay
IPI: Inferred from physical interaction
IMP: Inferred from mutant phenotype
IGI: Inferred from genetic interaction
IEP: Inferred from expression pattern
Compound Screening Libraries
Virtual Screening
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Drug Screening Service
PIH1D2 Protein-protein interaction Information
|
Type
|
Protein Name | Protein ID | Interactor | Interactor Species | Interactor ID | Detection Method | References |
|---|---|---|---|---|---|---|---|
|
Intra
|
PIH1D2 | Q8WWB5 | NF2 | Homo sapiens | P35240 | 32814053 | |
|
Intra
|
PIH1D2 | Q8WWB5 | NF2 | Homo sapiens | P35240 | 32814053 | |
|
Intra
|
PIH1D2 | Q8WWB5 | NF2 | Homo sapiens | P35240 | 32814053 | |
|
Intra
|
PIH1D2 | Q8WWB5 | ITGB3BP | Homo sapiens | Q13352-5 | 25416956 | |
|
Intra
|
PIH1D2 | Q8WWB5 | KRTAP12-2 | Homo sapiens | P59991 | 32296183 | |
|
Intra
|
PIH1D2 | Q8WWB5 | KRTAP12-2 | Homo sapiens | P59991 | 32296183 | |
|
Intra
|
PIH1D2 | Q8WWB5 | KRTAP12-4 | Homo sapiens | P60329 | 25416956 | |
|
Intra
|
PIH1D2 | Q8WWB5 | KRTAP12-4 | Homo sapiens | P60329 | 25416956 | |
|
Intra
|
PIH1D2 | Q8WWB5 | KRTAP12-4 | Homo sapiens | P60329 | 32296183 | |
|
Intra
|
PIH1D2 | Q8WWB5 | KRTAP12-4 | Homo sapiens | P60329 | 25416956 | |
|
Intra
|
PIH1D2 | Q8WWB5 | KRTAP12-4 | Homo sapiens | P60329 | 32296183 | |
|
Intra
|
PIH1D2 | Q8WWB5 | IQUB | Homo sapiens | Q8NA54 | 32296183 | |
|
Intra
|
PIH1D2 | Q8WWB5 | IQUB | Homo sapiens | Q8NA54 | 32296183 | |
|
Intra
|
PIH1D2 | Q8WWB5 | SSX3 | Homo sapiens | Q99909 | 32296183 | |
|
Intra
|
PIH1D2 | Q8WWB5 | PBX4 | Homo sapiens | Q9BYU1 | 32296183 | |
|
Intra
|
PIH1D2 | Q8WWB5 | PBX4 | Homo sapiens | Q9BYU1 | 32296183 | |
|
Intra
|
PIH1D2 | Q8WWB5 | PBX4 | Homo sapiens | Q9BYU1 | 32296183 | |
|
Intra
|
PIH1D2 | Q8WWB5 | PLEKHJ1 | Homo sapiens | Q9NW61 | 32296183 | |
|
Intra
|
PIH1D2 | Q8WWB5 | PLEKHJ1 | Homo sapiens | Q9NW61 | 32296183 | |
|
Intra
|
PIH1D2 | Q8WWB5 | PLEKHJ1 | Homo sapiens | Q9NW61 | 32296183 | |
|
Intra
|
PIH1D2 | Q8WWB5 | PRDM6 | Homo sapiens | Q9NQX0 | 32296183 | |
|
Intra
|
PIH1D2 | Q8WWB5 | PRDM6 | Homo sapiens | Q9NQX0 | 32296183 | |
|
Intra
|
PIH1D2 | Q8WWB5 | PRDM6 | Homo sapiens | Q9NQX0 | 32296183 | |
|
Intra
|
PIH1D2 | Q8WWB5 | ZNF438 | Homo sapiens | Q7Z4V0 | 32296183 | |
|
Intra
|
PIH1D2 | Q8WWB5 | ZNF438 | Homo sapiens | Q7Z4V0 | 32296183 | |
|
Intra
|
PIH1D2 | Q8WWB5 | MCCD1 | Homo sapiens | P59942 | 32296183 | |
|
Intra
|
PIH1D2 | Q8WWB5 | MCCD1 | Homo sapiens | P59942 | 32296183 | |
|
Intra
|
PIH1D2 | Q8WWB5 | CCNL2 | Homo sapiens | Q96S94-5 | 32296183 | |
|
Intra
|
PIH1D2 | Q8WWB5 | CCNL2 | Homo sapiens | Q96S94-5 | 32296183 | |
|
Intra
|
PIH1D2 | Q8WWB5 | CCNL2 | Homo sapiens | Q96S94-5 | 32296183 | |
|
Intra
|
PIH1D2 | Q8WWB5 | HSF4 | Homo sapiens | Q9ULV5-2 | 32296183 | |
|
Intra
|
PIH1D2 | Q8WWB5 | HES7 | Homo sapiens | Q9BYE0 | 32296183 | |
|
Intra
|
PIH1D2 | Q8WWB5 | HES7 | Homo sapiens | Q9BYE0 | 32296183 | |
|
Intra
|
PIH1D2 | Q8WWB5 | HES7 | Homo sapiens | Q9BYE0 | 32296183 | |
|
Intra
|
PIH1D2 | Q8WWB5 | RSPO4 | Homo sapiens | Q2I0M5 | 32296183 | |
|
Intra
|
PIH1D2 | Q8WWB5 | RSPO4 | Homo sapiens | Q2I0M5 | 32296183 | |
|
Intra
|
PIH1D2 | Q8WWB5 | TAF6 | Homo sapiens | P49848-3 | 32296183 | |
|
Intra
|
PIH1D2 | Q8WWB5 | TAF6 | Homo sapiens | P49848-3 | 32296183 | |
|
Intra
|
PIH1D2 | Q8WWB5 | ANKRD11 | Homo sapiens | X5D778 | 32296183 | |
|
Intra
|
PIH1D2 | Q8WWB5 | ANKRD11 | Homo sapiens | X5D778 | 32296183 | |
|
Intra
|
PIH1D2 | Q8WWB5 | ANKRD11 | Homo sapiens | X5D778 | 32296183 | |
|
Intra
|
PIH1D2 | Q8WWB5 | NOTO | Homo sapiens | A8MTQ0 | 32296183 | |
|
Intra
|
PIH1D2 | Q8WWB5 | NOTO | Homo sapiens | A8MTQ0 | 32296183 | |
|
Intra
|
PIH1D2 | Q8WWB5 | DSCAM | Homo sapiens | O60469 | 32296183 | |
|
Intra
|
PIH1D2 | Q8WWB5 | DSCAM | Homo sapiens | O60469 | 32296183 | |
|
Intra
|
PIH1D2 | Q8WWB5 | LAP3 | Homo sapiens | P28838 | 32296183 | |
|
Intra
|
PIH1D2 | Q8WWB5 | LAP3 | Homo sapiens | P28838 | 32296183 | |
|
Intra
|
PIH1D2 | Q8WWB5 | TBATA | Homo sapiens | Q96M53 | 32296183 | |
|
Intra
|
PIH1D2 | Q8WWB5 | TBATA | Homo sapiens | Q96M53 | 32296183 | |
|
Intra
|
PIH1D2 | Q8WWB5 | TBATA | Homo sapiens | Q96M53 | 32296183 | |
|
Intra
|
PIH1D2 | Q8WWB5 | GMCL1 | Homo sapiens | Q96IK5 | 32296183 | |
|
Intra
|
PIH1D2 | Q8WWB5 | GMCL1 | Homo sapiens | Q96IK5 | 32296183 | |
|
Intra
|
PIH1D2 | Q8WWB5 | GMCL1 | Homo sapiens | Q96IK5 | 32296183 | |
|
Intra
|
PIH1D2 | Q8WWB5 | ZBTB1 | Homo sapiens | Q9Y2K1 | 32296183 | |
|
Intra
|
PIH1D2 | Q8WWB5 | ZBTB1 | Homo sapiens | Q9Y2K1 | 32296183 | |
|
Intra
|
PIH1D2 | Q8WWB5 | ZBTB1 | Homo sapiens | Q9Y2K1 | 32296183 | |
|
Intra
|
PIH1D2 | Q8WWB5 | REL | Homo sapiens | Q04864 | 25416956 | |
|
Intra
|
PIH1D2 | Q8WWB5 | REL | Homo sapiens | Q04864 | 25416956 | |
|
Intra
|
PIH1D2 | Q8WWB5 | SLPI | Homo sapiens | P03973 | 32296183 | |
|
Intra
|
PIH1D2 | Q8WWB5 | SLPI | Homo sapiens | P03973 | 32296183 | |
|
Intra
|
PIH1D2 | Q8WWB5 | EXOSC5 | Homo sapiens | Q9NQT4 | 32296183 | |
|
Intra
|
PIH1D2 | Q8WWB5 | MED20 | Homo sapiens | Q9H944 | 32296183 | |
|
Intra
|
PIH1D2 | Q8WWB5 | MED20 | Homo sapiens | Q9H944 | 32296183 | |
|
Intra
|
PIH1D2 | Q8WWB5 | MED20 | Homo sapiens | Q9H944 | 32296183 | |
|
Intra
|
PIH1D2 | Q8WWB5 | CDC23 | Homo sapiens | Q9UJX2 | 32296183 | |
|
Intra
|
PIH1D2 | Q8WWB5 | NXF1 | Homo sapiens | Q9UBU9 | 32296183 | |
|
Intra
|
PIH1D2 | Q8WWB5 | ZNF688 | Homo sapiens | P0C7X2 | 32296183 | |
|
Intra
|
PIH1D2 | Q8WWB5 | ZNF688 | Homo sapiens | P0C7X2 | 32296183 | |
|
Intra
|
PIH1D2 | Q8WWB5 | DPH3 | Homo sapiens | Q96FX2 | 25416956 | |
|
Intra
|
PIH1D2 | Q8WWB5 | DPH3 | Homo sapiens | Q96FX2 | 32296183 | |
|
Intra
|
PIH1D2 | Q8WWB5 | DPH3 | Homo sapiens | Q96FX2 | 25416956 | |
|
Intra
|
PIH1D2 | Q8WWB5 | DPH3 | Homo sapiens | Q96FX2 | 25416956 | |
|
Intra
|
PIH1D2 | Q8WWB5 | GPRASP2 | Homo sapiens | Q96D09 | 32296183 | |
|
Intra
|
PIH1D2 | Q8WWB5 | GPRASP2 | Homo sapiens | Q96D09 | 32296183 | |
|
Intra
|
PIH1D2 | Q8WWB5 | GPRASP2 | Homo sapiens | Q96D09 | 32296183 | |
|
Intra
|
PIH1D2 | Q8WWB5 | HTRA2 | Homo sapiens | O43464 | 32814053 | |
|
Intra
|
PIH1D2 | Q8WWB5 | HTRA2 | Homo sapiens | O43464 | 32814053 | |
|
Intra
|
PIH1D2 | Q8WWB5 | HTRA2 | Homo sapiens | O43464 | 32814053 | |
|
Intra
|
PIH1D2 | Q8WWB5 | SPRED1 | Homo sapiens | Q7Z699 | 32296183 | |
|
Intra
|
PIH1D2 | Q8WWB5 | SPRED1 | Homo sapiens | Q7Z699 | 32814053 | |
|
Intra
|
PIH1D2 | Q8WWB5 | SPRED1 | Homo sapiens | Q7Z699 | 32814053 | |
|
Intra
|
PIH1D2 | Q8WWB5 | SPRED1 | Homo sapiens | Q7Z699 | 32814053 | |
|
Intra
|
PIH1D2 | Q8WWB5 | SPRED1 | Homo sapiens | Q7Z699 | 32296183 | |
|
Intra
|
PIH1D2 | Q8WWB5 | CT55 | Homo sapiens | Q8WUE5 | 32296183 | |
|
Intra
|
PIH1D2 | Q8WWB5 | CT55 | Homo sapiens | Q8WUE5 | 32296183 | |
|
Intra
|
PIH1D2 | Q8WWB5 | ZNF185 | Homo sapiens | O15231 | 32296183 | |
|
Intra
|
PIH1D2 | Q8WWB5 | ZNF185 | Homo sapiens | O15231 | 32296183 | |
|
Intra
|
PIH1D2 | Q8WWB5 | ITGB3BP | Homo sapiens | Q13352 | 32296183 | |
|
Intra
|
PIH1D2 | Q8WWB5 | ITGB3BP | Homo sapiens | Q13352 | 32296183 | |
|
Intra
|
PIH1D2 | Q8WWB5 | CBX8 | Homo sapiens | Q9HC52 | 32296183 | |
|
Intra
|
PIH1D2 | Q8WWB5 | COMMD3 | Homo sapiens | Q9UBI1 | 32296183 | |
|
Intra
|
PIH1D2 | Q8WWB5 | MDFI | Homo sapiens | Q99750 | 32296183 | |
|
Intra
|
PIH1D2 | Q8WWB5 | MDFI | Homo sapiens | Q99750 | 32296183 | |
|
Intra
|
PIH1D2 | Q8WWB5 | MDFI | Homo sapiens | Q99750 | 32296183 | |
|
Intra
|
PIH1D2 | Q8WWB5 | FRS3 | Homo sapiens | O43559 | 32296183 | |
|
Intra
|
PIH1D2 | Q8WWB5 | FRS3 | Homo sapiens | O43559 | 32296183 | |
|
Intra
|
PIH1D2 | Q8WWB5 | NTAQ1 | Homo sapiens | Q96HA8 | 32296183 | |
|
Intra
|
PIH1D2 | Q8WWB5 | ENKD1 | Homo sapiens | Q9H0I2 | 32296183 | |
|
Intra
|
PIH1D2 | Q8WWB5 | GFAP | Homo sapiens | P14136 | 25416956 | |
|
Intra
|
PIH1D2 | Q8WWB5 | TASOR2 | Homo sapiens | Q5VWN6 | 32296183 | |
|
Intra
|
PIH1D2 | Q8WWB5 | TASOR2 | Homo sapiens | Q5VWN6 | 32296183 | |
|
Intra
|
PIH1D2 | Q8WWB5 | TNNI1 | Homo sapiens | P19237 | 32296183 | |
|
Intra
|
PIH1D2 | Q8WWB5 | TNNI1 | Homo sapiens | P19237 | 32296183 | |
|
Intra
|
PIH1D2 | Q8WWB5 | SERTAD1 | Homo sapiens | Q9UHV2 | 32296183 | |
|
Intra
|
PIH1D2 | Q8WWB5 | SERTAD1 | Homo sapiens | Q9UHV2 | 32296183 | |
|
Intra
|
PIH1D2 | Q8WWB5 | SERTAD1 | Homo sapiens | Q9UHV2 | 32296183 | |
|
Intra
|
PIH1D2 | Q8WWB5 | MRFAP1L1 | Homo sapiens | Q96HT8 | 32296183 | |
|
Intra
|
PIH1D2 | Q8WWB5 | MRFAP1L1 | Homo sapiens | Q96HT8 | 32296183 | |
|
Intra
|
PIH1D2 | Q8WWB5 | MRFAP1L1 | Homo sapiens | Q96HT8 | 32296183 | |
|
Intra
|
PIH1D2 | Q8WWB5 | MRFAP1L1 | Homo sapiens | Q96HT8 | 25416956 | |
|
Intra
|
PIH1D2 | Q8WWB5 | CFAP206 | Homo sapiens | Q8IYR0 | 32296183 | |
|
Intra
|
PIH1D2 | Q8WWB5 | CFAP206 | Homo sapiens | Q8IYR0 | 32296183 | |
|
Intra
|
PIH1D2 | Q8WWB5 | PRPH | Homo sapiens | P41219 | 32814053 | |
|
Intra
|
PIH1D2 | Q8WWB5 | PRPH | Homo sapiens | P41219 | 32814053 | |
|
Intra
|
PIH1D2 | Q8WWB5 | PRPH | Homo sapiens | P41219 | 32814053 | |
|
Intra
|
PIH1D2 | Q8WWB5 | ZMAT5 | Homo sapiens | Q9UDW3 | 32296183 | |
|
Intra
|
PIH1D2 | Q8WWB5 | ZMAT5 | Homo sapiens | Q9UDW3 | 32296183 | |
|
Intra
|
PIH1D2 | Q8WWB5 | ZMAT5 | Homo sapiens | Q9UDW3 | 32296183 | |
|
Intra
|
PIH1D2 | Q8WWB5 | TTC23 | Homo sapiens | Q5W5X9-3 | 32296183 | |
|
Intra
|
PIH1D2 | Q8WWB5 | TTC23 | Homo sapiens | Q5W5X9-3 | 32296183 | |
|
Intra
|
PIH1D2 | Q8WWB5 | CDCA8 | Homo sapiens | Q53HL2 | 32296183 | |
|
Intra
|
PIH1D2 | Q8WWB5 | CDCA8 | Homo sapiens | Q53HL2 | 32296183 |
Cross: Cross-species interaction
Intra: Intraspecies interaction