SERTAD1 - SERTA domain containing 1 Gene

Also Known as SEI1; TRIPBR1; TRIP-Br1

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 29950

About SERTAD1

Cytogenetic location: 19q13.2 Genomic coordinates (GRCh38): 19:40,421,589-40,425,992 (from NCBI)

This gene has 1 transcript (splice variant), 86 orthologues and 1 paralogue. Ubiquitous expression in bone marrow (RPKM 19.1), gall bladder (RPKM 14.1) and 25 other tissues.

Summary

Predicted to be involved in epigenetic maintenance of chromatin in transcription-competent conformation. Predicted to act upstream of or within positive regulation of transcription by RNA polymerase II. Predicted to be located in cytoplasm. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

SERTAD1 Products (1)

mRNA Protein Name
NM_013376.4 NP_037508.2 SERTA domain-containing protein 1

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
16189514 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

SERTAD1 Protein Structure

SERTA

SERTA: SERTA motif (45 - 81)

  • 0
  • 100
  • 200
  • 236 a.a.
Protein Preferred Names Protein Names

SERTA domain-containing protein 1

  • CDK4-binding protein p34SEI

SERTAD1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
SERTAD1 Q9UHV2 PSORS1C2 Homo sapiens Q9UIG4
Validated Y2H
32296183
Intra
SERTAD1 Q9UHV2 SETD7 Homo sapiens Q8WTS6
Anti Tag CoIP
21988832
Intra
SERTAD1 Q9UHV2 SSX7 Homo sapiens Q7RTT5
Y2H Array
32296183
Intra
SERTAD1 Q9UHV2 CKS1B Homo sapiens P61024
Validated Y2H
32296183
Intra
SERTAD1 Q9UHV2 KLHL42 Homo sapiens Q9P2K6
Y2H Pooling
16189514
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS12731 SERTAD1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus SERTAD1 VGNC VGNC:65031
Macaca mulatta SERTAD1 VGNC VGNC:77263
Rattus norvegicus SERTAD1 RGD RGD:1549778
Canis familiaris SERTAD1 VGNC VGNC:46044
Bos taurus SERTAD1 VGNC VGNC:34483
Mus musculus SERTAD1 MGD MGI:1913438
Others SERTAD1 NCBI