FRS3 - fibroblast growth factor receptor substrate 3 Gene

Also Known as SNT2; FRS2B; SNT-2; FRS2beta; FRS2-beta

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 10817

About FRS3

Cytogenetic location: 6p21.1 Genomic coordinates (GRCh38): 6:41,770,176-41,779,900 (from NCBI)

This gene has 5 transcripts (splice variants), 205 orthologues and 7 paralogues. Broad expression in testis (RPKM 6.0), brain (RPKM 2.3) and 23 other tissues.

Summary

This gene encodes a substrate for the Fibroblast Growth Factor receptor. The encoded protein is found in the peripheral plasma membrane and links Fibroblast Growth Factor receptor stimulation to activators of Ras. The encoded protein down-regulates extracellular regulated kinase 2 through direct binding. [provided by RefSeq, Jul 2013]

FRS3 Products (1)

mRNA Protein Name
NM_006653.5 NP_006644.1 fibroblast growth factor receptor substrate 3

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables fibroblast growth factor receptor binding IPI
IPI: Inferred from physical interaction
9660748 GOA
enables identical protein binding IPI
IPI: Inferred from physical interaction
25814554 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
18985028 GOA
Biological Process GO Annotation Evidence References Source
acts upstream of or within fibroblast growth factor receptor signaling pathway IGI
IGI: Inferred from genetic interaction
9660748 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

FRS3 Protein Structure

IRS

IRS: PTB domain (IRS-1 type) (20 - 107)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 492 a.a.
Protein Preferred Names Protein Names

fibroblast growth factor receptor substrate 3

  • FGFR substrate 3

FRS3 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
FRS3 O43559 KRTAP10-8 Homo sapiens P60410
Y2H Array
32296183
Intra
FRS3 O43559 KRTAP10-8 Homo sapiens P60410
Y2H Prey Pooling
32296183
Intra
FRS3 O43559 KRTAP10-8 Homo sapiens P60410
Validated Y2H
32296183
Intra
FRS3 O43559 DCDC2B Homo sapiens A2VCK2
Y2H Array
32296183
Intra
FRS3 O43559 DCDC2B Homo sapiens A2VCK2
Y2H Prey Pooling
32296183
Intra
FRS3 O43559 ADAMTSL4 Homo sapiens Q6UY14-3
Y2H Array
25416956
Intra
FRS3 O43559 RIMBP3 Homo sapiens Q9UFD9
Y2H Prey Pooling
32296183
Intra
FRS3 O43559 RIMBP3 Homo sapiens Q9UFD9
Validated Y2H
32296183
Intra
FRS3 O43559 RIMBP3 Homo sapiens Q9UFD9
Y2H Array
32296183
Intra
FRS3 O43559 CREB5 Homo sapiens Q02930-3
Validated Y2H
32296183
Intra
FRS3 O43559 PIH1D2 Homo sapiens Q8WWB5
Validated Y2H
32296183
Intra
FRS3 O43559 TSGA10IP Homo sapiens Q3SY00
Validated Y2H
32296183
Intra
FRS3 O43559 TSGA10IP Homo sapiens Q3SY00
Y2H Array
32296183
Intra
FRS3 O43559 TSGA10IP Homo sapiens Q3SY00
Y2H Prey Pooling
32296183
Intra
FRS3 O43559 SLAIN1 Homo sapiens Q8ND83
Validated Y2H
32296183
Intra
FRS3 O43559 SLAIN1 Homo sapiens Q8ND83
Y2H Prey Pooling
32296183
Intra
FRS3 O43559 SLAIN1 Homo sapiens Q8ND83
Y2H Array
32296183
Intra
FRS3 O43559 KRT34 Homo sapiens O76011
Validated Y2H
32296183
Intra
FRS3 O43559 KRT34 Homo sapiens O76011
Y2H Prey Pooling
32296183
Intra
FRS3 O43559 KRT34 Homo sapiens O76011
Y2H Array
32296183
Intra
FRS3 O43559 KRT33B Homo sapiens Q14525
Y2H Prey Pooling
32296183
Intra
FRS3 O43559 KRT33B Homo sapiens Q14525
Validated Y2H
32296183
Intra
FRS3 O43559 KRT33B Homo sapiens Q14525
Y2H Array
32296183
Intra
FRS3 O43559 KRTAP11-1 Homo sapiens Q8IUC1
Validated Y2H
32296183
Intra
FRS3 O43559 KRTAP11-1 Homo sapiens Q8IUC1
Y2H Array
32296183
Intra
FRS3 O43559 KRTAP11-1 Homo sapiens Q8IUC1
Y2H Prey Pooling
32296183
Intra
FRS3 O43559 KRT35 Homo sapiens Q92764
Validated Y2H
32296183
Intra
FRS3 O43559 KRT35 Homo sapiens Q92764
Y2H Array
32296183
Intra
FRS3 O43559 KRT35 Homo sapiens Q92764
Y2H Prey Pooling
32296183
Intra
FRS3 O43559 PLB1 Homo sapiens Q6P1J6-2
Validated Y2H
32296183
Intra
FRS3 O43559 PLB1 Homo sapiens Q6P1J6-2
Y2H Array
32296183
Intra
FRS3 O43559 PLB1 Homo sapiens Q6P1J6-2
Y2H Prey Pooling
32296183
Intra
FRS3 O43559 SPATA12 Homo sapiens Q7Z6I5
Validated Y2H
32296183
Intra
FRS3 O43559 SPATA12 Homo sapiens Q7Z6I5
Y2H Array
32296183
Intra
FRS3 O43559 SPATA12 Homo sapiens Q7Z6I5
Y2H Prey Pooling
32296183
Intra
FRS3 O43559 KPRP Homo sapiens Q5T749
Validated Y2H
32296183
Intra
FRS3 O43559 KPRP Homo sapiens Q5T749
Y2H Array
32296183
Intra
FRS3 O43559 KPRP Homo sapiens Q5T749
Y2H Prey Pooling
32296183
Intra
FRS3 O43559 PRDM6 Homo sapiens Q9NQX0
Y2H Prey Pooling
32296183
Intra
FRS3 O43559 PRDM6 Homo sapiens Q9NQX0
Validated Y2H
32296183
Intra
FRS3 O43559 PRDM6 Homo sapiens Q9NQX0
Y2H Array
32296183
Intra
FRS3 O43559 ZFP90 Homo sapiens Q8TF47
Validated Y2H
32296183
Intra
FRS3 O43559 ZFP90 Homo sapiens Q8TF47
Y2H Array
32296183
Intra
FRS3 O43559 ZFP90 Homo sapiens Q8TF47
Y2H Prey Pooling
32296183
Intra
FRS3 O43559 TLE5 Homo sapiens Q08117-2
Validated Y2H
32296183
Intra
FRS3 O43559 TLE5 Homo sapiens Q08117-2
Y2H Array
32296183
Intra
FRS3 O43559 TLE5 Homo sapiens Q08117-2
Y2H Prey Pooling
32296183
Intra
FRS3 O43559 ZSCAN30 Homo sapiens Q86W11
Validated Y2H
32296183
Intra
FRS3 O43559 ZSCAN30 Homo sapiens Q86W11
Y2H Array
32296183
Intra
FRS3 O43559 ZSCAN30 Homo sapiens Q86W11
Y2H Prey Pooling
32296183
Intra
FRS3 O43559 PCSK5 Homo sapiens Q92824-2
Validated Y2H
32296183
Intra
FRS3 O43559 PCSK5 Homo sapiens Q92824-2
Y2H Prey Pooling
32296183
Intra
FRS3 O43559 PCSK5 Homo sapiens Q92824-2
Y2H Array
32296183
Intra
FRS3 O43559 VGLL3 Homo sapiens A8MV65-2
Y2H Array
32296183
Intra
FRS3 O43559 VGLL3 Homo sapiens A8MV65-2
Y2H Prey Pooling
32296183
Intra
FRS3 O43559 SPAG8 Homo sapiens Q99932-2
Validated Y2H
32296183
Intra
FRS3 O43559 SPAG8 Homo sapiens Q99932-2
Y2H Array
32296183
Intra
FRS3 O43559 SPAG8 Homo sapiens Q99932-2
Y2H Prey Pooling
32296183
Intra
FRS3 O43559 KRTAP1-1 Homo sapiens Q07627
Y2H Array
32296183
Intra
FRS3 O43559 KRTAP1-1 Homo sapiens Q07627
Y2H Prey Pooling
32296183
Intra
FRS3 O43559 KRTAP1-1 Homo sapiens Q07627
Validated Y2H
32296183
Intra
FRS3 O43559 KRTAP6-2 Homo sapiens Q3LI66
Validated Y2H
32296183
Intra
FRS3 O43559 KRTAP6-2 Homo sapiens Q3LI66
Y2H Array
32296183
Intra
FRS3 O43559 KRTAP6-2 Homo sapiens Q3LI66
Y2H Prey Pooling
32296183
Intra
FRS3 O43559 ZNF438 Homo sapiens Q7Z4V0
Validated Y2H
32296183
Intra
FRS3 O43559 ZNF438 Homo sapiens Q7Z4V0
Y2H Array
32296183
Intra
FRS3 O43559 ZNF438 Homo sapiens Q7Z4V0
Y2H Prey Pooling
32296183
Intra
FRS3 O43559 ACTMAP Homo sapiens Q5BKX5-3
Y2H Array
32296183
Intra
FRS3 O43559 ACTMAP Homo sapiens Q5BKX5-3
Validated Y2H
32296183
Intra
FRS3 O43559 ACTMAP Homo sapiens Q5BKX5-3
Y2H Prey Pooling
32296183
Intra
FRS3 O43559 POF1B Homo sapiens Q8WVV4-1
Y2H Prey Pooling
32296183
Intra
FRS3 O43559 POF1B Homo sapiens Q8WVV4-1
Validated Y2H
32296183
Intra
FRS3 O43559 POF1B Homo sapiens Q8WVV4-1
Y2H Array
32296183
Intra
FRS3 O43559 SAXO4 Homo sapiens Q7Z5V6-2
Y2H Prey Pooling
32296183
Intra
FRS3 O43559 SAXO4 Homo sapiens Q7Z5V6-2
Y2H Array
32296183
Intra
FRS3 O43559 SAXO4 Homo sapiens Q7Z5V6-2
Validated Y2H
32296183
Intra
FRS3 O43559 ZMIZ2 Homo sapiens Q8NF64-3
Y2H Array
32296183
Intra
FRS3 O43559 ZMIZ2 Homo sapiens Q8NF64-3
Y2H Prey Pooling
32296183
Intra
FRS3 O43559 ZMIZ2 Homo sapiens Q8NF64-3
Validated Y2H
32296183
Intra
FRS3 O43559 TGM7 Homo sapiens Q96PF1
Y2H Prey Pooling
32296183
Intra
FRS3 O43559 TGM7 Homo sapiens Q96PF1
Validated Y2H
32296183
Intra
FRS3 O43559 TGM7 Homo sapiens Q96PF1
Y2H Array
32296183
Intra
FRS3 O43559 WWOX Homo sapiens Q9NZC7-5
Validated Y2H
32296183
Intra
FRS3 O43559 WWOX Homo sapiens Q9NZC7-5
Y2H Prey Pooling
32296183
Intra
FRS3 O43559 WWOX Homo sapiens Q9NZC7-5
Y2H Array
32296183
Intra
FRS3 O43559 ANAPC11 Homo sapiens Q9NYG5-2
Validated Y2H
32296183
Intra
FRS3 O43559 ANAPC11 Homo sapiens Q9NYG5-2
Y2H Prey Pooling
32296183
Intra
FRS3 O43559 ANAPC11 Homo sapiens Q9NYG5-2
Y2H Array
32296183
Intra
FRS3 O43559 ESM1 Homo sapiens Q9NQ30
Y2H Prey Pooling
32296183
Intra
FRS3 O43559 ESM1 Homo sapiens Q9NQ30
Validated Y2H
32296183
Intra
FRS3 O43559 ESM1 Homo sapiens Q9NQ30
Y2H Array
32296183
Intra
FRS3 O43559 ZNF69 Homo sapiens Q9UC07-2
Y2H Prey Pooling
32296183
Intra
FRS3 O43559 ZNF69 Homo sapiens Q9UC07-2
Validated Y2H
32296183
Intra
FRS3 O43559 ZNF69 Homo sapiens Q9UC07-2
Y2H Array
32296183
Intra
FRS3 O43559 MBD3L1 Homo sapiens Q8WWY6
Validated Y2H
32296183
Intra
FRS3 O43559 MBD3L1 Homo sapiens Q8WWY6
Y2H Array
32296183
Intra
FRS3 O43559 MBD3L1 Homo sapiens Q8WWY6
Y2H Prey Pooling
32296183
Intra
FRS3 O43559 TSC1 Homo sapiens Q86WV8
Y2H Prey Pooling
32296183
Intra
FRS3 O43559 TSC1 Homo sapiens Q86WV8
Y2H Array
32296183
Intra
FRS3 O43559 TSC1 Homo sapiens Q86WV8
Validated Y2H
32296183
Intra
FRS3 O43559 KCNJ5-AS1 Homo sapiens Q8TAV5
Validated Y2H
32296183
Intra
FRS3 O43559 KCNJ5-AS1 Homo sapiens Q8TAV5
Y2H Prey Pooling
32296183
Intra
FRS3 O43559 KCNJ5-AS1 Homo sapiens Q8TAV5
Y2H Array
32296183
Intra
FRS3 O43559 ATP23 Homo sapiens Q9Y6H3
Y2H Array
32296183
Intra
FRS3 O43559 ATP23 Homo sapiens Q9Y6H3
Y2H Prey Pooling
32296183
Intra
FRS3 O43559 ATP23 Homo sapiens Q9Y6H3
Validated Y2H
32296183
Intra
FRS3 O43559 UNKL Homo sapiens Q9H9P5-5
Y2H Prey Pooling
32296183
Intra
FRS3 O43559 UNKL Homo sapiens Q9H9P5-5
Y2H Array
32296183
Intra
FRS3 O43559 UNKL Homo sapiens Q9H9P5-5
Validated Y2H
32296183
Intra
FRS3 O43559 SLC22A18AS Homo sapiens Q8N1D0-2
Y2H Prey Pooling
32296183
Intra
FRS3 O43559 SLC22A18AS Homo sapiens Q8N1D0-2
Validated Y2H
32296183
Intra
FRS3 O43559 SLC22A18AS Homo sapiens Q8N1D0-2
Y2H Array
32296183
Intra
FRS3 O43559 STH Homo sapiens Q8IWL8
Validated Y2H
32296183
Intra
FRS3 O43559 STH Homo sapiens Q8IWL8
Y2H Prey Pooling
32296183
Intra
FRS3 O43559 STH Homo sapiens Q8IWL8
Y2H Array
32296183
Intra
FRS3 O43559 ID3 Homo sapiens Q02535
Y2H Array
32296183
Intra
FRS3 O43559 ID3 Homo sapiens Q02535
Validated Y2H
32296183
Intra
FRS3 O43559 ID3 Homo sapiens Q02535
Y2H Prey Pooling
32296183
Intra
FRS3 O43559 ANKRD55 Homo sapiens Q3KP44
Y2H Prey Pooling
32296183
Intra
FRS3 O43559 ANKRD55 Homo sapiens Q3KP44
Y2H Array
32296183
Intra
FRS3 O43559 ANKRD55 Homo sapiens Q3KP44
Validated Y2H
32296183
Intra
FRS3 O43559 HOXD12 Homo sapiens P35452-2
Y2H Prey Pooling
32296183
Intra
FRS3 O43559 HOXD12 Homo sapiens P35452-2
Validated Y2H
32296183
Intra
FRS3 O43559 HOXD12 Homo sapiens P35452-2
Y2H Array
32296183
Intra
FRS3 O43559 DPEP2NB Homo sapiens A0A0U1RQF7
Y2H Array
32296183
Intra
FRS3 O43559 DPEP2NB Homo sapiens A0A0U1RQF7
Y2H Prey Pooling
32296183
Intra
FRS3 O43559 ISY1 Homo sapiens Q9ULR0-1
Y2H Array
32296183
Intra
FRS3 O43559 ISY1 Homo sapiens Q9ULR0-1
Y2H Prey Pooling
32296183
Intra
FRS3 O43559 ISY1 Homo sapiens Q9ULR0-1
Validated Y2H
32296183
Intra
FRS3 O43559 NOTCH2NLC Homo sapiens P0DPK4
Validated Y2H
32296183
Intra
FRS3 O43559 NOTCH2NLC Homo sapiens P0DPK4
Y2H Array
32296183
Intra
FRS3 O43559 NOTCH2NLC Homo sapiens P0DPK4
Y2H Prey Pooling
32296183
Intra
FRS3 O43559 BLZF1 Homo sapiens Q9H2G9
Validated Y2H
32296183
Intra
FRS3 O43559 BLZF1 Homo sapiens Q9H2G9
Y2H Prey Pooling
32296183
Intra
FRS3 O43559 BLZF1 Homo sapiens Q9H2G9
Y2H Array
32296183
Intra
FRS3 O43559 ZNF552 Homo sapiens Q9H707
Validated Y2H
32296183
Intra
FRS3 O43559 ZNF552 Homo sapiens Q9H707
Y2H Array
32296183
Intra
FRS3 O43559 ZNF552 Homo sapiens Q9H707
Y2H Prey Pooling
32296183
Intra
FRS3 O43559 ZNF124 Homo sapiens Q15973
Y2H Array
32296183
Intra
FRS3 O43559 ZNF124 Homo sapiens Q15973
Validated Y2H
32296183
Intra
FRS3 O43559 ZNF124 Homo sapiens Q15973
Y2H Prey Pooling
32296183
Intra
FRS3 O43559 MIIP Homo sapiens Q5JXC2
Y2H Array
32296183
Intra
FRS3 O43559 MIIP Homo sapiens Q5JXC2
Validated Y2H
32296183
Intra
FRS3 O43559 MIIP Homo sapiens Q5JXC2
Y2H Prey Pooling
32296183
Intra
FRS3 O43559 CDPF1 Homo sapiens Q6NVV7
Y2H Prey Pooling
32296183
Intra
FRS3 O43559 CDPF1 Homo sapiens Q6NVV7
Validated Y2H
32296183
Intra
FRS3 O43559 CDPF1 Homo sapiens Q6NVV7
Y2H Array
32296183
Intra
FRS3 O43559 KRT76 Homo sapiens Q01546
Validated Y2H
32296183
Intra
FRS3 O43559 KRT76 Homo sapiens Q01546
Y2H Array
32296183
Intra
FRS3 O43559 KRT76 Homo sapiens Q01546
Y2H Prey Pooling
32296183
Intra
FRS3 O43559 PDLIM7 Homo sapiens Q9NR12
Y2H Prey Pooling
32296183
Intra
FRS3 O43559 PDLIM7 Homo sapiens Q9NR12
Validated Y2H
32296183
Intra
FRS3 O43559 PDLIM7 Homo sapiens Q9NR12
Y2H Array
32296183
Intra
FRS3 O43559 COPS3 Homo sapiens Q9UNS2
Y2H Prey Pooling
32296183
Intra
FRS3 O43559 COPS3 Homo sapiens Q9UNS2
Y2H Array
32296183
Intra
FRS3 O43559 COPS3 Homo sapiens Q9UNS2
Validated Y2H
32296183
Intra
FRS3 O43559 AKAP8L Homo sapiens Q9ULX6
Y2H Prey Pooling
32296183
Intra
FRS3 O43559 AKAP8L Homo sapiens Q9ULX6
Validated Y2H
32296183
Intra
FRS3 O43559 AKAP8L Homo sapiens Q9ULX6
Y2H Array
32296183
Intra
FRS3 O43559 TRAF4 Homo sapiens Q9BUZ4
Y2H Prey Pooling
32296183
Intra
FRS3 O43559 TRAF4 Homo sapiens Q9BUZ4
Validated Y2H
32296183
Intra
FRS3 O43559 TRAF4 Homo sapiens Q9BUZ4
Y2H Array
32296183
Intra
FRS3 O43559 CYSRT1 Homo sapiens A8MQ03
Y2H Array
32296183
Intra
FRS3 O43559 CYSRT1 Homo sapiens A8MQ03
Y2H Prey Pooling
32296183
Intra
FRS3 O43559 CCN3 Homo sapiens P48745
Validated Y2H
32296183
Intra
FRS3 O43559 CCN3 Homo sapiens P48745
Y2H Array
32296183
Intra
FRS3 O43559 CCN3 Homo sapiens P48745
Y2H Prey Pooling
32296183
Intra
FRS3 O43559 GATA1 Homo sapiens P15976
Y2H Prey Pooling
25416956
Intra
FRS3 O43559 PLLP Homo sapiens Q9Y342
Y2H Prey Pooling
32296183
Intra
FRS3 O43559 PLLP Homo sapiens Q9Y342
Validated Y2H
32296183
Intra
FRS3 O43559 PLLP Homo sapiens Q9Y342
Y2H Array
32296183
Intra
FRS3 O43559 TCP10L Homo sapiens Q8TDR4
Y2H Prey Pooling
32296183
Intra
FRS3 O43559 TCP10L Homo sapiens Q8TDR4
Validated Y2H
32296183
Intra
FRS3 O43559 TCP10L Homo sapiens Q8TDR4
Y2H Array
32296183
Intra
FRS3 O43559 SOCS4 Homo sapiens Q8WXH5
Lumier
25814554
Intra
FRS3 O43559 TCF4 Homo sapiens P15884
Y2H Array
25416956
Intra
FRS3 O43559 INCA1 Homo sapiens Q0VD86
Y2H Prey Pooling
32296183
Intra
FRS3 O43559 INCA1 Homo sapiens Q0VD86
Validated Y2H
32296183
Intra
FRS3 O43559 INCA1 Homo sapiens Q0VD86
Y2H Array
32296183
Intra
FRS3 O43559 ID2 Homo sapiens Q02363
Validated Y2H
32296183
Intra
FRS3 O43559 ID2 Homo sapiens Q02363
Y2H Array
32296183
Intra
FRS3 O43559 ID2 Homo sapiens Q02363
Y2H Prey Pooling
32296183
Intra
FRS3 O43559 KATNBL1 Homo sapiens Q9H079
Validated Y2H
32296183
Intra
FRS3 O43559 KATNBL1 Homo sapiens Q9H079
Y2H Array
32296183
Intra
FRS3 O43559 KATNBL1 Homo sapiens Q9H079
Y2H Prey Pooling
32296183
Intra
FRS3 O43559 TLE5 Homo sapiens Q08117
Y2H Prey Pooling
25416956
Intra
FRS3 O43559 CFAP68 Homo sapiens Q9H5F2
Y2H Array
32296183
Intra
FRS3 O43559 CFAP68 Homo sapiens Q9H5F2
Y2H Prey Pooling
32296183
Intra
FRS3 O43559 CFAP68 Homo sapiens Q9H5F2
Validated Y2H
32296183
Intra
FRS3 O43559 LINGO1 Homo sapiens Q96FE5
Validated Y2H
32296183
Intra
FRS3 O43559 LINGO1 Homo sapiens Q96FE5
Y2H Array
32296183
Intra
FRS3 O43559 LINGO1 Homo sapiens Q96FE5
Y2H Prey Pooling
32296183
Intra
FRS3 O43559 FRS3 Homo sapiens O43559
Y2H Prey Pooling
32296183
Intra
FRS3 O43559 FRS3 Homo sapiens O43559
Y2H Array
32296183
Intra
FRS3 O43559 RFX6 Homo sapiens Q8HWS3
Y2H Prey Pooling
25416956
Intra
FRS3 O43559 PIK3R3 Homo sapiens Q92569
Y2H Array
25814554
Intra
FRS3 O43559 TRIP6 Homo sapiens Q15654
Validated Y2H
32296183
Intra
FRS3 O43559 RFX6 Homo sapiens Q8HWS3
Y2H Prey Pooling
32296183
Intra
FRS3 O43559 TRIP6 Homo sapiens Q15654
Y2H Array
32296183
Intra
FRS3 O43559 RFX6 Homo sapiens Q8HWS3
Validated Y2H
32296183
Intra
FRS3 O43559 TRIP6 Homo sapiens Q15654
Y2H Array
25416956
Intra
FRS3 O43559 FRS3 Homo sapiens O43559
Y2H Array
25814554
Intra
FRS3 O43559 FRS3 Homo sapiens O43559
Lumier
25814554
Intra
FRS3 O43559 RFX6 Homo sapiens Q8HWS3
Y2H Array
32296183
Intra
FRS3 O43559 TRIP6 Homo sapiens Q15654
Y2H Prey Pooling
32296183
Intra
FRS3 O43559 FRS3 Homo sapiens O43559
Validated Y2H
32296183
Intra
FRS3 O43559 C22orf39 Homo sapiens Q6P5X5
Validated Y2H
32296183
Intra
FRS3 O43559 C22orf39 Homo sapiens Q6P5X5
Y2H Array
32296183
Intra
FRS3 O43559 C22orf39 Homo sapiens Q6P5X5
Y2H Prey Pooling
32296183
Intra
FRS3 O43559 KIAA0408 Homo sapiens Q6ZU52
Validated Y2H
32296183
Intra
FRS3 O43559 KIAA0408 Homo sapiens Q6ZU52
Y2H Array
32296183
Intra
FRS3 O43559 KIAA0408 Homo sapiens Q6ZU52
Y2H Prey Pooling
32296183
Intra
FRS3 O43559 PLSCR1 Homo sapiens O15162
Validated Y2H
25416956
Intra
FRS3 O43559 PLSCR1 Homo sapiens O15162
Y2H Array
25416956
Intra
FRS3 O43559 ZNF446 Homo sapiens Q9NWS9-2
Validated Y2H
32296183
Intra
FRS3 O43559 ZNF446 Homo sapiens Q9NWS9-2
Y2H Prey Pooling
32296183
Intra
FRS3 O43559 ZNF446 Homo sapiens Q9NWS9-2
Y2H Array
32296183
Intra
FRS3 O43559 ZNF417 Homo sapiens Q8TAU3
Y2H Prey Pooling
32296183
Intra
FRS3 O43559 ZNF417 Homo sapiens Q8TAU3
Validated Y2H
32296183
Intra
FRS3 O43559 ZNF417 Homo sapiens Q8TAU3
Y2H Array
32296183
Intra
FRS3 O43559 HOXA1 Homo sapiens P49639
Y2H Array
32296183
Intra
FRS3 O43559 HOXA1 Homo sapiens P49639
Y2H Prey Pooling
32296183
Intra
FRS3 O43559 HOXA1 Homo sapiens P49639
Validated Y2H
32296183
Intra
FRS3 O43559 CBY2 Homo sapiens Q8NA61
Y2H Prey Pooling
25416956
Intra
FRS3 O43559 CBY2 Homo sapiens Q8NA61
Validated Y2H
25416956
Intra
FRS3 O43559 SPRY2 Homo sapiens O43597
Validated Y2H
25416956
Intra
FRS3 O43559 SPRY2 Homo sapiens O43597
Y2H Prey Pooling
25416956
Intra
FRS3 O43559 SPRY2 Homo sapiens O43597
Y2H Array
25416956
Intra
FRS3 O43559 CATSPER1 Homo sapiens Q8NEC5
Validated Y2H
32296183
Intra
FRS3 O43559 COL8A1 Homo sapiens P27658
Validated Y2H
32296183
Intra
FRS3 O43559 IKZF3 Homo sapiens Q9UKT9
Y2H Prey Pooling
32296183
Intra
FRS3 O43559 IKZF3 Homo sapiens Q9UKT9
Validated Y2H
32296183
Intra
FRS3 O43559 IKZF3 Homo sapiens Q9UKT9
Y2H Array
32296183
Intra
FRS3 O43559 SCNM1 Homo sapiens Q9BWG6
Validated Y2H
32296183
Intra
FRS3 O43559 NADSYN1 Homo sapiens Q6IA69
Validated Y2H
32296183
Intra
FRS3 O43559 NADSYN1 Homo sapiens Q6IA69
Y2H Array
32296183
Intra
FRS3 O43559 NADSYN1 Homo sapiens Q6IA69
Y2H Prey Pooling
32296183
Intra
FRS3 O43559 STK16 Homo sapiens O75716
Validated Y2H
32296183
Intra
FRS3 O43559 KRTAP3-2 Homo sapiens Q9BYR7
Validated Y2H
32296183
Intra
FRS3 O43559 KRTAP3-2 Homo sapiens Q9BYR7
Y2H Array
32296183
Intra
FRS3 O43559 KRTAP3-2 Homo sapiens Q9BYR7
Y2H Prey Pooling
32296183
Intra
FRS3 O43559 LRRC18 Homo sapiens Q8N456
Y2H Prey Pooling
32296183
Intra
FRS3 O43559 LRRC18 Homo sapiens Q8N456
Validated Y2H
32296183
Intra
FRS3 O43559 LRRC18 Homo sapiens Q8N456
Y2H Array
32296183
Intra
FRS3 O43559 WDR83 Homo sapiens Q9BRX9
Y2H Prey Pooling
32296183
Intra
FRS3 O43559 WDR83 Homo sapiens Q9BRX9
Validated Y2H
32296183
Intra
FRS3 O43559 WDR83 Homo sapiens Q9BRX9
Y2H Array
32296183
Intra
FRS3 O43559 TSPAN4 Homo sapiens O14817
Y2H Array
32296183
Intra
FRS3 O43559 TSPAN4 Homo sapiens O14817
Y2H Prey Pooling
32296183
Intra
FRS3 O43559 GATA1 Homo sapiens P15976-2
Y2H Prey Pooling
32296183
Intra
FRS3 O43559 GATA1 Homo sapiens P15976-2
Validated Y2H
32296183
Intra
FRS3 O43559 GATA1 Homo sapiens P15976-2
Y2H Array
32296183
Intra
FRS3 O43559 NOTCH2NLA Homo sapiens Q7Z3S9
Validated Y2H
25416956
Intra
FRS3 O43559 ECM1 Homo sapiens Q16610
Y2H Prey Pooling
32296183
Intra
FRS3 O43559 ECM1 Homo sapiens Q16610
Y2H Array
32296183
Intra
FRS3 O43559 ECM1 Homo sapiens Q16610
Validated Y2H
32296183
Intra
FRS3 O43559 KRT31 Homo sapiens Q15323
Y2H Prey Pooling
32296183
Intra
FRS3 O43559 KRT31 Homo sapiens Q15323
Validated Y2H
32296183
Intra
FRS3 O43559 KRT31 Homo sapiens Q15323
Y2H Array
32296183
Intra
FRS3 O43559 DMRT3 Homo sapiens Q9NQL9
Validated Y2H
32296183
Intra
FRS3 O43559 HCK Homo sapiens P08631-2
Lumier
25814554
Intra
FRS3 O43559 KRTAP3-1 Homo sapiens Q9BYR8
Y2H Array
32296183
Intra
FRS3 O43559 KRTAP3-1 Homo sapiens Q9BYR8
Validated Y2H
32296183
Intra
FRS3 O43559 KRTAP3-1 Homo sapiens Q9BYR8
Y2H Prey Pooling
32296183
Intra
FRS3 O43559 Q9WMX2-PRO_0000037548 Hepatitis C virus Q9WMX2-PRO_0000037548
Pull Down
18985028
Intra
FRS3 O43559 Q9WMX2-PRO_0000037548 Hepatitis C virus Q9WMX2-PRO_0000037548
Y2H
18985028
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05113 FRS3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus FRS3 VGNC VGNC:29121
Macaca mulatta FRS3 VGNC VGNC:72731
Mus musculus FRS3 MGD MGI:2135965
Rattus norvegicus FRS3 RGD RGD:1310226
Felis catus FRS3 VGNC VGNC:62369
Canis familiaris FRS3 VGNC VGNC:40987
Others FRS3 NCBI