ZFP90 - ZFP90 zinc finger protein Gene

Also Known as FIK; NK10; ZNF756; zfp-90

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 146198

Summary

This gene encodes a member of the Zinc Finger Protein family that modulates gene expression. The encoded protein derepresses the transcription of certain fetal cardiac genes and may contribute to the genetic reprogramming that occurs during the development of Heart Failure. Genome wide association studies have identified this gene among Ulcerative Colitis risk loci. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Mar 2015]
Ubiquitous expression in ovary (RPKM 6.9), brain (RPKM 6.4) and 25 other tissues.

ZFP90 Products (6)

mRNA Protein Name
NM_001305203.2 NP_001292132.1 zinc finger protein 90 homolog isoform 1
NM_001305204.2 NP_001292133.1 zinc finger protein 90 homolog isoform 2
NM_001305206.2 NP_001292135.1 zinc finger protein 90 homolog isoform 3
NM_001305207.2 NP_001292136.1 zinc finger protein 90 homolog isoform 4
NM_001305208.2 NP_001292137.1 zinc finger protein 90 homolog isoform 3
NM_133458.4 NP_597715.2 zinc finger protein 90 homolog isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
23543754 GOA
Biological Process GO Annotation Evidence References Source
involved in positive regulation of DNA-templated transcription IMP
IMP: Inferred from mutant phenotype
21284946 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ZFP90 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
ZFP90 Q8TF47 ABI2 Homo sapiens Q9NYB9-2
Validated Y2H
32296183
Intra
ZFP90 Q8TF47 NEK6 Homo sapiens Q9HC98-4
Validated Y2H
32296183
Intra
ZFP90 Q8TF47 CPNE7 Homo sapiens Q9UBL6-2
Validated Y2H
32296183
Intra
ZFP90 Q8TF47 TDRKH Homo sapiens Q9Y2W6
Validated Y2H
32296183
Intra
ZFP90 Q8TF47 MALSU1 Homo sapiens Q96EH3
Validated Y2H
32296183
Intra
ZFP90 Q8TF47 MALSU1 Homo sapiens Q96EH3
Y2H Prey Pooling
32296183
Intra
ZFP90 Q8TF47 EXOSC5 Homo sapiens Q9NQT4
Validated Y2H
32296183
Intra
ZFP90 Q8TF47 GTPBP3 Homo sapiens Q969Y2
Validated Y2H
32296183
Intra
ZFP90 Q8TF47 ENKD1 Homo sapiens Q9H0I2
Validated Y2H
32296183
Intra
ZFP90 Q8TF47 GCC1 Homo sapiens Q96CN9
Validated Y2H
32296183
Intra
ZFP90 Q8TF47 TEKT4 Homo sapiens Q8WW24
Validated Y2H
32296183
Intra
ZFP90 Q8TF47 TBC1D22B Homo sapiens Q9NU19
Validated Y2H
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS16046 ZFP91 Human Pre-designed siRNA Set A Pre-designed Set / Unkown