MALSU1 - mitochondrial assembly of ribosomal large subunit 1 Gene

Also Known as mtRsfA; C7orf30

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 115416

Summary

Enables mitochondrial large ribosomal subunit binding activity. Involved in mitochondrial large ribosomal subunit assembly and negative regulation of mitochondrial translation. Located in mitochondrion. [provided by Alliance of Genome Resources, Jun 2026]
Ubiquitous expression in kidney (RPKM 9.8), fat (RPKM 9.6) and 25 other tissues.

MALSU1 Products (1)

mRNA Protein Name
NM_138446.2 NP_612455.1 mitochondrial assembly of ribosomal large subunit protein 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables mitochondrial large ribosomal subunit binding IDA
IDA: Inferred from direct assay
28892042 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
25416956 GOA
Biological Process GO Annotation Evidence References Source
involved in negative regulation of mitochondrial translation IDA
IDA: Inferred from direct assay
22829778 GOA
involved in ribosomal large subunit biogenesis IMP
IMP: Inferred from mutant phenotype
22238376 GOA
Cellular Component GO Annotation Evidence References Source
located in mitochondrion IDA
IDA: Inferred from direct assay
16548050 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

MALSU1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
MALSU1 Q96EH3 SP6 Homo sapiens Q3SY56
Y2H Array
32296183
Intra
MALSU1 Q96EH3 SP6 Homo sapiens Q3SY56
Y2H Prey Pooling
32296183
Intra
MALSU1 Q96EH3 ZFP90 Homo sapiens Q8TF47
Y2H Array
32296183
Intra
MALSU1 Q96EH3 MEOX2 Homo sapiens Q6FHY5
Y2H Array
32296183
Intra
MALSU1 Q96EH3 MEOX2 Homo sapiens Q6FHY5
Y2H Prey Pooling
32296183
Intra
MALSU1 Q96EH3 INCA1 Homo sapiens Q0VD86
Y2H Array
32296183
Intra
MALSU1 Q96EH3 INCA1 Homo sapiens Q0VD86
Y2H Prey Pooling
32296183
Intra
MALSU1 Q96EH3 DCTD Homo sapiens P32321
Y2H Array
32296183
Intra
MALSU1 Q96EH3 DCTD Homo sapiens P32321
Y2H Prey Pooling
32296183
Intra
MALSU1 Q96EH3 DCTD Homo sapiens P32321
Y2H Array
25416956
Intra
MALSU1 Q96EH3 NTAQ1 Homo sapiens Q96HA8
Validated Y2H
32296183
Intra
MALSU1 Q96EH3 ZNF426 Homo sapiens Q9BUY5
Y2H Prey Pooling
32296183
Intra
MALSU1 Q96EH3 ZNF426 Homo sapiens Q9BUY5
Validated Y2H
32296183
Intra
MALSU1 Q96EH3 ZNF426 Homo sapiens Q9BUY5
Y2H Array
32296183
Intra
MALSU1 Q96EH3 MYBPHL Homo sapiens A2RUH7
Y2H Array
32296183
Intra
MALSU1 Q96EH3 MYBPHL Homo sapiens A2RUH7
Y2H Prey Pooling
32296183
Intra
MALSU1 Q96EH3 PLEKHG4 Homo sapiens Q58EX7
Y2H Prey Pooling
32296183
Intra
MALSU1 Q96EH3 PLEKHG4 Homo sapiens Q58EX7
Y2H Array
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction