1. Gene
  2. MIIP - migration and invasion inhibitory protein Gene

MIIP - migration and invasion inhibitory protein Gene

Homo sapiens

Also known as IIP45

Gene ID: 60672 | Gene type: protein coding

About MIIP

Cytogenetic location: 1p36.22 Genomic coordinates (GRCh38): 1:12,019,498-12,032,045 (from NCBI)

This gene has 7 transcripts (splice variants) and 169 orthologues. Ubiquitous expression in bone marrow (RPKM 14.3), testis (RPKM 8.7) and 24 other tissues.

Summary

This gene encodes a protein that interacts with the oncogene protein insulin-like growth factor binding protein 2 and may function as an inhibitor of cell migration and invasion. This protein also interacts with the cell division protein 20 and may be involved in regulating mitotic progression. This protein may function as a tumor suppressor by inhibiting the growth or certain cancers. [provided by RefSeq, Sep 2011]

MIIP Products(1)

mRNA Protein Name
NM_021933.4 NP_068752.2 migration and invasion-inhibitory protein
Protein Preferred Names Protein Names

migration and invasion-inhibitory protein

IGFBP2-binding protein

Related Diseases

Diseases Alias
Prolapse Of Urethra

Urethrocele

Glioma
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Mus musculus MIIP MGD MGI:106506
Felis catus MIIP VGNC VGNC:63506
Macaca mulatta MIIP VGNC VGNC:74829
Rattus norvegicus MIIP RGD RGD:1587376
Bos taurus MIIP VGNC VGNC:31475
Canis familiaris MIIP VGNC VGNC:43234