TSC22D4 - TSC22 domain family member 4 Gene

Also Known as THG1; THG-1; TILZ2

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 81628

About TSC22D4

Cytogenetic location: 7q22.1 Genomic coordinates (GRCh38): 7:100,466,519-100,479,214 (from NCBI)

This gene has 6 transcripts (splice variants), 112 orthologues and 3 paralogues. Ubiquitous expression in brain (RPKM 27.0), spleen (RPKM 25.5) and 25 other tissues.

Summary

TSC22D4 is a member of the TSC22 domain family of leucine zipper transcriptional regulators (see TSC22D3; MIM 300506) (Kester et al., 1999 [PubMed 10488076]; Fiorenza et al., 2001 [PubMed 11707329]).[supplied by OMIM, Mar 2008]

TSC22D4 Products (2)

mRNA Protein Name
NM_001303043.2 NP_001289972.1 TSC22 domain family protein 4 isoform a
NM_030935.5 NP_112197.1 TSC22 domain family protein 4 isoform a

TSC22D4 Protein Structure

TSC22

TSC22: TSC-22/dip/bun family (326 - 380)

  • 0
  • 100
  • 200
  • 300
  • 395 a.a.
Protein Preferred Names Protein Names

TSC22 domain family protein 4

  • TSC22-related-inducible leucine zipper protein 2

TSC22D4 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
TSC22D4 Q9Y3Q8 CCDC146 Homo sapiens Q8IYE0-2
Y2H Array
25416956
Intra
TSC22D4 Q9Y3Q8 POLR1C Homo sapiens O15160
Y2H Array
25416956
Intra
TSC22D4 Q9Y3Q8 POLR1C Homo sapiens O15160
Y2H Prey Pooling
25416956
Intra
TSC22D4 Q9Y3Q8 KIF1B Homo sapiens O60333-2
Validated Y2H
32814053
Intra
TSC22D4 Q9Y3Q8 KIF1B Homo sapiens O60333-2
Y2H Pooling
32814053
Intra
TSC22D4 Q9Y3Q8 KIF1B Homo sapiens O60333-2
Y2H Array
32814053
Intra
TSC22D4 Q9Y3Q8 NRBP2 Homo sapiens Q9NSY0
Anti Tag CoIP
33961781
Intra
TSC22D4 Q9Y3Q8 NRBP2 Homo sapiens Q9NSY0
Anti Tag CoIP
28514442
Intra
TSC22D4 Q9Y3Q8 PRKAA1 Homo sapiens Q13131
Y2H Prey Pooling
25416956
Intra
TSC22D4 Q9Y3Q8 PRKAA2 Homo sapiens P54646
Y2H Prey Pooling
25416956
Intra
TSC22D4 Q9Y3Q8 CHAT Homo sapiens P28329-3
Y2H Array
32814053
Intra
TSC22D4 Q9Y3Q8 CHAT Homo sapiens P28329-3
Y2H Pooling
32814053
Intra
TSC22D4 Q9Y3Q8 CHAT Homo sapiens P28329-3
Validated Y2H
32814053
Intra
TSC22D4 Q9Y3Q8 q9y649_human Homo sapiens Q9Y649
Validated Y2H
32814053
Intra
TSC22D4 Q9Y3Q8 q9y649_human Homo sapiens Q9Y649
Y2H Array
32814053
Intra
TSC22D4 Q9Y3Q8 q9y649_human Homo sapiens Q9Y649
Y2H Pooling
32814053
Intra
TSC22D4 Q9Y3Q8 SMAD3 Homo sapiens P84022
Y2H
21988832
Intra
TSC22D4 Q9Y3Q8 SMAD3 Homo sapiens P84022
Anti Tag CoIP
21988832
Intra
TSC22D4 Q9Y3Q8 FGFR3 Homo sapiens P22607
Y2H Pooling
32814053
Intra
TSC22D4 Q9Y3Q8 FGFR3 Homo sapiens P22607
Validated Y2H
32814053
Intra
TSC22D4 Q9Y3Q8 FGFR3 Homo sapiens P22607
Y2H Array
32814053
Intra
TSC22D4 Q9Y3Q8 HSPB1 Homo sapiens P04792
Y2H Array
32814053
Intra
TSC22D4 Q9Y3Q8 HSPB1 Homo sapiens P04792
Y2H Pooling
32814053
Intra
TSC22D4 Q9Y3Q8 HSPB1 Homo sapiens P04792
Validated Y2H
32814053
Intra
TSC22D4 Q9Y3Q8 AIFM1 Homo sapiens O95831
Y2H Array
16713569
Intra
TSC22D4 Q9Y3Q8 PIH1D1 Homo sapiens Q9NWS0
Y2H Prey Pooling
25416956
Intra
TSC22D4 Q9Y3Q8 PIH1D1 Homo sapiens Q9NWS0
Validated Y2H
25416956
Intra
TSC22D4 Q9Y3Q8 PIH1D1 Homo sapiens Q9NWS0
Y2H Array
25416956
Intra
TSC22D4 Q9Y3Q8 APIP Homo sapiens Q96GX9
Anti Tag CoIP
33961781
Intra
TSC22D4 Q9Y3Q8 PPL Homo sapiens O60437
Validated Y2H
25416956
Intra
TSC22D4 Q9Y3Q8 PPL Homo sapiens O60437
Y2H Array
25416956
Intra
TSC22D4 Q9Y3Q8 RNF11 Homo sapiens Q9Y3C5
Validated Y2H
32814053
Intra
TSC22D4 Q9Y3Q8 RNF11 Homo sapiens Q9Y3C5
Y2H Array
32814053
Intra
TSC22D4 Q9Y3Q8 RNF11 Homo sapiens Q9Y3C5
Y2H Pooling
32814053
Intra
TSC22D4 Q9Y3Q8 MYLIP Homo sapiens Q8WY64
Validated Y2H
25416956
Intra
TSC22D4 Q9Y3Q8 MYLIP Homo sapiens Q8WY64
Y2H Prey Pooling
25416956
Intra
TSC22D4 Q9Y3Q8 MYLIP Homo sapiens Q8WY64
Y2H Array
25416956
Intra
TSC22D4 Q9Y3Q8 PIN1 Homo sapiens Q13526
Validated Y2H
25416956
Intra
TSC22D4 Q9Y3Q8 PIN1 Homo sapiens Q13526
Y2H Array
25416956
Intra
TSC22D4 Q9Y3Q8 PIN1 Homo sapiens Q13526
Y2H Prey Pooling
25416956
Intra
TSC22D4 Q9Y3Q8 WFS1 Homo sapiens O76024
Validated Y2H
32814053
Intra
TSC22D4 Q9Y3Q8 WFS1 Homo sapiens O76024
Y2H Pooling
32814053
Intra
TSC22D4 Q9Y3Q8 WFS1 Homo sapiens O76024
Y2H Array
32814053
Intra
TSC22D4 Q9Y3Q8 LMO2 Homo sapiens P25791
Y2H Prey Pooling
25416956
Intra
TSC22D4 Q9Y3Q8 LMO2 Homo sapiens P25791
Validated Y2H
25416956
Intra
TSC22D4 Q9Y3Q8 LMO2 Homo sapiens P25791
Y2H Array
25416956
Intra
TSC22D4 Q9Y3Q8 ZBTB24 Homo sapiens O43167
Y2H Array
25416956
Intra
TSC22D4 Q9Y3Q8 ZMYND10 Homo sapiens O75800
Y2H Prey Pooling
25416956
Intra
TSC22D4 Q9Y3Q8 NRBP1 Homo sapiens Q9UHY1
Y2H Array
31515488
Intra
TSC22D4 Q9Y3Q8 NRBP1 Homo sapiens Q9UHY1
Anti Tag CoIP
28514442
Intra
TSC22D4 Q9Y3Q8 NRBP1 Homo sapiens Q9UHY1
Anti Tag CoIP
33961781
Intra
TSC22D4 Q9Y3Q8 NRBP1 Homo sapiens Q9UHY1
Anti Tag CoIP
25416956
Intra
TSC22D4 Q9Y3Q8 NRBP1 Homo sapiens Q9UHY1
Y2H
21516116
Intra
TSC22D4 Q9Y3Q8 KEAP1 Homo sapiens Q14145
Confocal
21988832
Intra
TSC22D4 Q9Y3Q8 KEAP1 Homo sapiens Q14145
Anti Tag CoIP
33961781
Intra
TSC22D4 Q9Y3Q8 KEAP1 Homo sapiens Q14145
Y2H
21988832
Intra
TSC22D4 Q9Y3Q8 MAD2L1 Homo sapiens Q13257
Anti Tag CoIP
33961781
Intra
TSC22D4 Q9Y3Q8 MAD2L1 Homo sapiens Q13257
Validated Y2H
25416956
Intra
TSC22D4 Q9Y3Q8 MAD2L1 Homo sapiens Q13257
Anti Tag CoIP
28514442
Intra
TSC22D4 Q9Y3Q8 MAD2L1 Homo sapiens Q13257
Y2H Array
25416956
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15136 TSC22D4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus TSC22D4 VGNC VGNC:66609
Bos taurus TSC22D4 VGNC VGNC:108136
Macaca mulatta TSC22D4 VGNC VGNC:81784
Mus musculus TSC22D4 MGD MGI:1926079
Canis familiaris TSC22D4 VGNC VGNC:47894
Rattus norvegicus TSC22D4 RGD RGD:1584380
Others TSC22D4 NCBI