Mcl-1 inhibitor 18
Mcl-1 inhibitor 18 (compound 57) is a myeloid cell leukemia 1 (Mcl-1) inhibitor, and can be used for study of cancer.
For research use only. We do not sell to patients.
- Formula: C50H60ClN5O10
- Molecular Weight:926.49
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| NCI-H929 | IC50 |
1.1 μM
Compound: 57
|
Cytotoxicity against human NCI-H929 cells assessed as cell viability by measuring caspase 3/7 activity measured after 6 hrs by luminescence assay
Cytotoxicity against human NCI-H929 cells assessed as cell viability by measuring caspase 3/7 activity measured after 6 hrs by luminescence assay
|
[PMID: 38306405] |
Chemical Information
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Molecular Weight 926.49
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Formula C50H60ClN5O10
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SMILES
CCOC1=CC(OC2=CC(C)=C(C(C)=C2)Cl)=CC3=C1OCC(N[C@@H]4CC[C@H](CC(N[C@H](C(N[C@@H](C(N[C@H](C(O)=O)CC5=CC=C(C=C5)OC3)=O)CC6=CC=CN=C6)=O)CC(C)C)=O)CC4)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)