MEOX2 - mesenchyme homeobox 2 Gene

Homo sapiens

Also known as GAX; MOX2

Gene ID: 4223 | Gene type: protein coding

About MEOX2

Cytogenetic location: 7p21.2 Genomic coordinates (GRCh38): 7:15,611,212-15,686,683 (from NCBI)

This gene has 1 transcript (splice variant), 233 orthologues and 1 paralogue. Biased expression in placenta (RPKM 25.8), fat (RPKM 23.2) and 13 other tissues.

Summary

This gene encodes a member of a subfamily of non-clustered, diverged, antennapedia-like homeobox-containing genes. The encoded protein may play a role in the regulation of vertebrate limb myogenesis. Mutations in the related mouse protein may be associated with craniofacial and/or skeletal abnormalities, in addition to neurovascular dysfunction observed in Alzheimer's disease. [provided by RefSeq, Jul 2008]

MEOX2 Products(1)

mRNA	Protein	Name
NM_005924.5	NP_005915.2	homeobox protein MOX-2

MEOX2 Protein Structure

Homeobox

0
100
200
304 a.a.

Protein Preferred Names

Protein Names

homeobox protein MOX-2

growth arrest-specific homeobox

Related Diseases

Diseases

Alias

Female Stress Incontinence

Female Urinary Stress Incontinence

Stress Incontinence - Female

Cleft Palate With Or Without Ankyloglossia, X-Linked

Cleft Palate With Ankyloglossia	CPX
X-Linked Cleft Palate And Ankyloglossia	X-Linked Cleft Palate With Or Without Ankyloglossia
X-Linked Cleft Palate	X-Linked Cleft Palate With Ankyloglossia
Cleft Palate, With/Without Ankyloglossia, X-Linked

Cleft Palate, Isolated

Cleft Palate	Isolated Cleft Palate
CPI	Cp
Palatoschisis	Cleft Palate Isolated
Uranostaphyloschisis	Congenital Fissure Of Palate
Cleft Of Secondary Palate

Vesicoureteral Reflux

Vesico-Ureteral Reflux

Orofacial Cleft

Cleft, Orofacial

Alzheimer Disease, Familial, 1

Alzheimer Disease	Alzheimer'S Disease
Presenile And Senile Dementia	AD1
Alzheimer Disease, Susceptibility To	Alzheimer Disease, Late-Onset, Susceptibility To
Alzheimer Disease 1, Familial	AD
Familial Alzheimer Disease	Alzheimer Disease, Late-Onset
Alzheimers Dementia	Alzheimer Dementia
Alzheimer Sclerosis	Alzheimer Syndrome
Alzheimer-Type Dementia	Dat
Primary Senile Degenerative Dementia	Sdat
Alzheimer Disease 1	Autosomal Dominant Alzheimer Disease
Early-Onset Alzheimer Disease With Cerebral Amyloid Angiopathy	Late Onset Alzheimer Disease
Alzheimers Disease	Alzheimer Disease, Early-Onset, With Cerebral Amyloid Angiopathy
Late-Onset Alzheimers Disease	Alzheimer'S Disease Pathway Kegg
Dementia Due To Alzheimer'S Disease	Alzheimer Disease Type 1
Alzheimers

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS08335	MEOX2 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	MEOX2	VGNC	VGNC:68235
Macaca mulatta	MEOX2	VGNC	VGNC:74703
Canis familiaris	MEOX2	VGNC	VGNC:43158
Mus musculus	MEOX2	MGD	MGI:103219
Bos taurus	MEOX2	VGNC	VGNC:31387
Rattus norvegicus	MEOX2	RGD	RGD:3079

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