FUT11 - fucosyltransferase 11 Gene

Also Known as FUCTXI

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 170384

About FUT11

Cytogenetic location: 10q22.2 Genomic coordinates (GRCh38): 10:73,772,276-73,780,254 (from NCBI)

This gene has 4 transcripts (splice variants), 210 orthologues and 7 paralogues. Ubiquitous expression in placenta (RPKM 8.2), lung (RPKM 6.0) and 24 other tissues.

Summary

Predicted to enable alpha-(1->3)-fucosyltransferase activity. Predicted to be involved in fucosylation. Predicted to be located in Golgi cisterna membrane. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]

FUT11 Products (2)

mRNA Protein Name
NM_001284194.2 NP_001271123.1 alpha-(1,3)-fucosyltransferase 11 isoform 2 precursor
NM_173540.3 NP_775811.2 alpha-(1,3)-fucosyltransferase 11 isoform 1 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables fucosyltransferase activity IDA
IDA: Inferred from direct assay
19088067 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
25416956 GOA
Biological Process GO Annotation Evidence References Source
involved in N-glycan fucosylation IDA
IDA: Inferred from direct assay
19088067 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

FUT11 Protein Structure

Glyco_transf_10

Glyco_transf_10: Glycosyltransferase family 10 (fucosyltransferase) C-term (72 - 394)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 492 a.a.
Protein Preferred Names Protein Names

alpha-(1,3)-fucosyltransferase 11

  • alpha (1,3) fucosyltransferase

FUT11 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
FUT11 Q495W5 MEOX2 Homo sapiens P50222
Y2H Array
25416956
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-E70159 Fucosyltransferase 11 / Unkown
HY-RS05152 FUT11 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22520 Fut11 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29041 Fut11 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris FUT11 VGNC VGNC:41013
Bos taurus FUT11 VGNC VGNC:29149
Rattus norvegicus FUT11 RGD RGD:628731
Macaca mulatta FUT11 VGNC VGNC:72744
Mus musculus FUT11 MGD MGI:1920318
Felis catus FUT11 VGNC VGNC:62393
Others FUT11 NCBI