2. Gene
  3. TBCEL - tubulin folding cofactor E like Gene

TBCEL - tubulin folding cofactor E like Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as El; LRRC35

Gene ID: 219899 | Gene type: protein coding

About TBCEL

Cytogenetic location: 11q23.3 Genomic coordinates (GRCh38): 11:121,024,102-121,090,776 (from NCBI)

This gene has 10 transcripts (splice variants), 283 orthologues and 1 paralogue. Ubiquitous expression in testis (RPKM 8.9), thyroid (RPKM 6.7) and 25 other tissues.

Summary

Predicted to enable alpha-tubulin binding activity. Predicted to be involved in microtubule Cytoskeleton organization; post-chaperonin tubulin folding pathway; and tubulin complex assembly. Predicted to be located in Cytoskeleton. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

TBCEL Products(3)

mRNA Protein Name
NM_001130047.3 NP_001123519.1 tubulin-specific chaperone cofactor E-like protein
NM_001363644.2 NP_001350573.1 tubulin-specific chaperone cofactor E-like protein
NM_152715.5 NP_689928.3 tubulin-specific chaperone cofactor E-like protein

TBCEL Protein Structure

Ubiquitin_2

Ubiquitin_2: Ubiquitin-like domain (353 - 421)

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  • 400
  • 424 a.a.
Protein Preferred Names Protein Names

tubulin-specific chaperone cofactor E-like protein

E-like

Related Diseases

Diseases Alias
Megalencephalic Leukoencephalopathy With Subcortical Cysts 2b

Megalencephalic Leukoencephalopathy With Subcortical Cysts 2b, Remitting, With Or Without Mental Retardation
Megalencephalic Leukoencephalopathy With Subcortical Cysts 2a

MLC2A

Leukoencephalopathy, Megalencephalic, With Subcortical Cysts, 2a

Leukoencephalopathy, Megalencephalic, With Subcortical Cysts, Type 2a
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS14255 TBCEL Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus TBCEL VGNC VGNC:35654
Rattus norvegicus TBCEL RGD RGD:1308880
Mus musculus TBCEL MGD MGI:1925543
Canis familiaris TBCEL VGNC VGNC:47158
Felis catus TBCEL VGNC VGNC:99691