TP53BP1 - tumor protein p53 binding protein 1 Gene

Also Known as p202; 53BP1; TDRD30; p53BP1

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 7158

About TP53BP1

Cytogenetic location: 15q15.3 Genomic coordinates (GRCh38): 15:43,403,061-43,510,640 (from NCBI)

This gene has 17 transcripts (splice variants) and 201 orthologues. Ubiquitous expression in brain (RPKM 10.8), testis (RPKM 9.9) and 25 other tissues.

Summary

This gene encodes a protein that functions in the DNA double-strand break repair pathway choice, promoting non-homologous end joining (NHEJ) pathways, and limiting homologous recombination. This protein plays multiple roles in the DNA damage response, including promoting checkpoint signaling following DNA damage, acting as a scaffold for recruitment of DNA damage response proteins to damaged chromatin, and promoting NHEJ pathways by limiting end resection following a double-strand break. These roles are also important during V(D)J recombination, class switch recombination and at unprotected telomeres. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2017]

TP53BP1 Products (5)

mRNA	Protein	Name
NM_001141979.3	NP_001135451.1	TP53-binding protein 1 isoform 2
NM_001141980.3	NP_001135452.1	TP53-binding protein 1 isoform 1
NM_001355001.2	NP_001341930.1	TP53-binding protein 1 isoform 4
NM_001411050.1	NP_001397979.1	TP53-binding protein 1 isoform 5
NM_005657.4	NP_005648.1	TP53-binding protein 1 isoform 3

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	References	Source
enables RNA polymerase II-specific DNA-binding transcription factor binding	IPI IPI: Inferred from physical interaction	17805299	GOA
enables histone reader activity	IDA IDA: Inferred from direct assay	23760478	GOA
enables methylated histone binding	IDA IDA: Inferred from direct assay	22373579	GOA
enables p53 binding	IPI IPI: Inferred from physical interaction	14985081	GOA
enables protein binding	IPI IPI: Inferred from physical interaction	11877378	GOA
enables transcription coregulator activity	IMP IMP: Inferred from mutant phenotype	17805299	GOA
enables ubiquitin-modified histone reader activity	IDA IDA: Inferred from direct assay	22492721	GOA

Biological Process GO Annotation	Evidence	References	Source
acts upstream of or within DNA damage response	IDA IDA: Inferred from direct assay	17500065	GOA
involved in DNA damage response	IDA IDA: Inferred from direct assay	27153538	GOA
involved in double-strand break repair via classical nonhomologous end joining	IDA IDA: Inferred from direct assay	27153538	GOA
involved in double-strand break repair via nonhomologous end joining	IDA IDA: Inferred from direct assay	23333306	GOA
involved in negative regulation of double-strand break repair via homologous recombination	IDA IDA: Inferred from direct assay	23333306	GOA
involved in positive regulation of isotype switching	IDA IDA: Inferred from direct assay	23345425	GOA
involved in positive regulation of isotype switching	IMP IMP: Inferred from mutant phenotype	23760478	GOA
involved in positive regulation of transcription by RNA polymerase II	IMP IMP: Inferred from mutant phenotype	17805299	GOA
involved in protein homooligomerization	IDA IDA: Inferred from direct assay	23345425	GOA
involved in protein localization to site of double-strand break	IDA IDA: Inferred from direct assay	37696958	GOA

Cellular Component GO Annotation	Evidence	References	Source
colocalizes with chromosome, telomeric region	IDA IDA: Inferred from direct assay	15149599	GOA
located in cytoplasm	IDA IDA: Inferred from direct assay	9748285	GOA
located in nucleus	IDA IDA: Inferred from direct assay	28241136	GOA
is active in site of double-strand break	IDA IDA: Inferred from direct assay	22492721	GOA
located in site of double-strand break	IDA IDA: Inferred from direct assay	23333306	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

TP53BP1 Protein Structure

53-BP1_Tudor

0
400
800
1200
1600
1977 a.a.

Protein Preferred Names	Protein Names
TP53-binding protein 1	p53-binding protein 1

TP53BP1 Protein-protein interaction Information

Type	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	References
Intra	TP53BP1	Q12888	DNM2	Homo sapiens	P50570-2	Y2H Pooling	32814053
Intra	TP53BP1	Q12888	DNM2	Homo sapiens	P50570-2	Validated Y2H	32814053
Intra	TP53BP1	Q12888	DNM2	Homo sapiens	P50570-2	Y2H Array	32814053
Intra	TP53BP1	Q12888	DMWD	Homo sapiens	G5E9A7	Y2H Array	32814053
Intra	TP53BP1	Q12888	DMWD	Homo sapiens	G5E9A7	Validated Y2H	32814053
Intra	TP53BP1	Q12888	DMWD	Homo sapiens	G5E9A7	Y2H Pooling	32814053
Intra	TP53BP1	Q12888	ANKS1A	Homo sapiens	Q49AR9	Validated Y2H	32296183
Intra	TP53BP1	Q12888	VAMP1	Homo sapiens	P23763-3	Validated Y2H	32814053
Intra	TP53BP1	Q12888	VAMP1	Homo sapiens	P23763-3	Y2H Pooling	32814053
Intra	TP53BP1	Q12888	VAMP1	Homo sapiens	P23763-3	Y2H Array	32814053
Intra	TP53BP1	Q12888	C10orf55	Homo sapiens	Q5SWW7	Validated Y2H	32296183
Intra	TP53BP1	Q12888	C10orf55	Homo sapiens	Q5SWW7	Y2H Prey Pooling	32296183
Intra	TP53BP1	Q12888	C10orf55	Homo sapiens	Q5SWW7	Y2H Array	32296183
Intra	TP53BP1	Q12888	OXER1	Homo sapiens	Q8TDS5	Validated Y2H	32296183
Intra	TP53BP1	Q12888	OXER1	Homo sapiens	Q8TDS5	Y2H Array	32296183
Intra	TP53BP1	Q12888	OXER1	Homo sapiens	Q8TDS5	Y2H Prey Pooling	32296183
Cross	TP53BP1	Q12888	Paxip1	Mus musculus	Q6NZQ4	Anti Tag CoIP	19124460
Intra	TP53BP1	Q12888	VRK1	Homo sapiens	Q99986	Pull Down	22621922
Intra	TP53BP1	Q12888	VRK1	Homo sapiens	Q99986	Phosphotransferase	22621922
Intra	TP53BP1	Q12888	SHLD2	Homo sapiens	Q86V20-2	Anti Tag CoIP	29789392
Intra	TP53BP1	Q12888	VAC14	Homo sapiens	Q08AM6	Y2H Prey Pooling	32296183
Intra	TP53BP1	Q12888	VAC14	Homo sapiens	Q08AM6	Y2H Array	32296183
Intra	TP53BP1	Q12888	UBAP2	Homo sapiens	Q5T6F2	Validated Y2H	32296183
Intra	TP53BP1	Q12888	UBAP2	Homo sapiens	Q5T6F2	Y2H Prey Pooling	32296183
Intra	TP53BP1	Q12888	UBAP2	Homo sapiens	Q5T6F2	Y2H Array	32296183
Intra	TP53BP1	Q12888	H4C16	Homo sapiens	P62805	Far-WB	16415788
Intra	TP53BP1	Q12888	H4C16	Homo sapiens	P62805	Pull Down	16415788
Intra	TP53BP1	Q12888	H4C16	Homo sapiens	P62805	Pull Down	22373579
Intra	TP53BP1	Q12888	H4C16	Homo sapiens	P62805	Pull Down	27153538
Intra	TP53BP1	Q12888	H4C16	Homo sapiens	P62805	SPR	16415788
Intra	TP53BP1	Q12888	ZNHIT1	Homo sapiens	O43257	Anti Bait CoIP	17380123
Intra	TP53BP1	Q12888	BRCA1	Homo sapiens	P38398	Confocal	18001824
Intra	TP53BP1	Q12888	BRCA1	Homo sapiens	P38398	BioID	29656893
Intra	TP53BP1	Q12888	VIM	Homo sapiens	P08670	Y2H Array	32814053
Intra	TP53BP1	Q12888	VIM	Homo sapiens	P08670	Y2H Pooling	32814053
Intra	TP53BP1	Q12888	VIM	Homo sapiens	P08670	Validated Y2H	32814053
Intra	TP53BP1	Q12888	H2BC10	Homo sapiens	P62807	Crosslink	27462807
Intra	TP53BP1	Q12888	H2BC10	Homo sapiens	P62807	Pull Down	27462807
Intra	TP53BP1	Q12888	TP53	Homo sapiens	P04637	Anti Bait CoIP	17805299
Intra	TP53BP1	Q12888	PLK1	Homo sapiens	P53350	Protein Kinase Assay	20126263
Intra	TP53BP1	Q12888	PLK1	Homo sapiens	P53350	Pull Down	20126263
Intra	TP53BP1	Q12888	PLK1	Homo sapiens	P53350	Anti Bait CoIP	20126263
Intra	TP53BP1	Q12888	H2AX	Homo sapiens	P16104	IF	18001825
Intra	TP53BP1	Q12888	H2AX	Homo sapiens	P16104	IF	20075863
Intra	TP53BP1	Q12888	H2AX	Homo sapiens	P16104	Imaging	17024177
Intra	TP53BP1	Q12888	H2AX	Homo sapiens	P16104	Pull Down	12607005
Intra	TP53BP1	Q12888	ATM	Homo sapiens	Q13315	BioID	29656893
Intra	TP53BP1	Q12888	ATM	Homo sapiens	Q13315	Phosphotransferase	22621922
Intra	TP53BP1	Q12888	PMP22	Homo sapiens	A0A6Q8PF08	Y2H Pooling	32814053
Intra	TP53BP1	Q12888	PMP22	Homo sapiens	A0A6Q8PF08	Validated Y2H	32814053
Intra	TP53BP1	Q12888	PMP22	Homo sapiens	A0A6Q8PF08	Y2H Array	32814053
Intra	TP53BP1	Q12888	SPRED1	Homo sapiens	Q7Z699	Y2H Array	32814053
Intra	TP53BP1	Q12888	SPRED1	Homo sapiens	Q7Z699	Y2H Pooling	32814053
Intra	TP53BP1	Q12888	SPRED1	Homo sapiens	Q7Z699	Validated Y2H	32814053
Intra	TP53BP1	Q12888	PECAM1	Homo sapiens	P16284	Y2H Array	32814053
Intra	TP53BP1	Q12888	PECAM1	Homo sapiens	P16284	Y2H Pooling	32814053
Intra	TP53BP1	Q12888	PECAM1	Homo sapiens	P16284	Validated Y2H	32814053
Intra	TP53BP1	Q12888	PAXIP1	Homo sapiens	Q6ZW49	Anti Tag CoIP	15456759
Intra	TP53BP1	Q12888	CCDC120	Homo sapiens	Q96HB5	Validated Y2H	32296183
Intra	TP53BP1	Q12888	MEOX2	Homo sapiens	P50222	Y2H Prey Pooling	25416956
Intra	TP53BP1	Q12888	NCOA6	Homo sapiens	Q14686	Anti Bait CoIP	19433796
Intra	TP53BP1	Q12888	H3C1	Homo sapiens	P68431	Far-WB	16415788
Intra	TP53BP1	Q12888	H3C1	Homo sapiens	P68431	Pull Down	16415788
Intra	TP53BP1	Q12888	H3C1	Homo sapiens	P68431	SPR	16415788
Intra	TP53BP1	Q12888	H3C1	Homo sapiens	P68431	Protein Array	16415788
Intra	TP53BP1	Q12888	KLHDC7B	Homo sapiens	Q96G42	Y2H Array	32296183
Intra	TP53BP1	Q12888	KLHDC7B	Homo sapiens	Q96G42	Y2H Prey Pooling	32296183
Intra	TP53BP1	Q12888	KLHDC7B	Homo sapiens	Q96G42	Validated Y2H	32296183
Intra	TP53BP1	Q12888	ATP1A3	Homo sapiens	P13637	Validated Y2H	32814053
Intra	TP53BP1	Q12888	ATP1A3	Homo sapiens	P13637	Y2H Array	32814053
Intra	TP53BP1	Q12888	ATP1A3	Homo sapiens	P13637	Y2H Pooling	32814053

Cross: Cross-species interaction Intra: Intraspecies interaction

TP53BP1 Antibodies

Cat. No.	Product Name	Application	Reactivity
HY-P80001	53BP1 Antibody (YA649)	WB, ICC/IF, IHC-P, FC	Human, Mouse, Rat
HY-P84521	53BP1 Antibody (YA4218)	IHC-P, FC, ELISA	Human
HY-P84521A	53BP1 Antibody (YA4218)(PBS only)	IHC-P, FC, ELISA	Human
HY-P86435	53BP1 Antibody (YA6127)	WB, ICC/IF, IP, ELISA	Human

Related Diseases

Diseases	Alias
Microcephaly And Chorioretinopathy 3
Microcephaly And Chorioretinopathy, Autosomal Recessive, 3	MCCRP3 Microcephaly And Chorioretinopathy, Autosomal Recessive, Type 3
Microcephaly Chorioretinopathy Recessive Form
Breast Cancer	Breast Carcinoma Male Breast Cancer Breast Cancer, Familial Malignant Neoplasm Of Breast Breast Cancer, Susceptibility To Breast Cancer, Early-Onset Malignant Tumor Of Breast Carcinoma Of Male Breast Breast Cancer, Invasive Ductal Breast Cancer, Protection Against Breast Cancer, Somatic Breast Cancer, Male Breast Cancer, Lobular, Somatic Breast Tumor Mammary Cancer Mammary Tumor Malignant Neoplasm Of Male Breast Mammary Carcinoma Male Breast Carcinoma Familial Cancer Of Breast Invasive Ductal Breast Carcinoma Breast Cancer Susceptibility Breast Cancer, Male, Susceptibility To Breast Cancer, Early-Onset, Susceptibility To Malignant Tumor Of The Breast Mammary Neoplasm Primary Breast Cancer Neoplasm Of Male Breast Carcinoma Of Breast Breast Cancer In Men Familial Breast Cancer Cancer Of Breast BC Breast Cancer Familial Breast Cancer Familial Male Breast Cancer, Familial Male Breast Male Carcinoma Breast Neoplasms Breast Neoplasms, Male Mammary Tumors Mammary Carcinomas Cancer, Breast Cancer, Breast, Susceptibility Invasive Breast Ductal Carcinoma Breast Neoplasm Susceptibility To Breast Cancer Mammary Neoplasms Animal Mammary Neoplasms Primary Malignant Neoplasm Of Breast Infiltrating Ductal Carcinoma Of Breast Infiltrating Duct Carcinoma Of Unspecified Site Infiltrating Ductular Carcinoma Of Unspecified Site Invasive Breast Carcinoma Of No Special Type Microinvasive Carcinoma Of Breast Carcinoma With Apocrine Differentiation
Autosomal Recessive Chorioretinopathy-Microcephaly Syndrome	Autosomal Recessive Chorioretinopathy-Microcephaly-Intellectual Disability Syndrome
Riddle Syndrome	RIDL Radiosensitivity-Immunodeficiency-Dysmorphic Features-Learning Difficulties Syndrome Rnf168 Deficiency Radiosensitivity, Immunodeficiency, Dysmorphic Facial Features, And Learning Difficulties Radiosensitivity, Immunodeficiency, Dysmorphic Features, And Learning Difficulties
Ataxia-Telangiectasia	Ataxia Telangiectasia Louis-Bar Syndrome AT At1 Ataxia-Telangiectasia Syndrome Ataxia - Telangiectasia Variant Boder-Sedgwick Syndrome Louis Bar Syndrome Cerebello-Oculocutaneous Telangiectasia Immunodeficiency With Ataxia Telangiectasia A-T Ataxia Telangiectasia Syndrome Atm Telangiectasia, Cerebello-Oculocutaneous Ataxia-Telangiectasia Variant
Myeloproliferative Disorder, Chronic, With Eosinophilia	Myeloproliferative Disorder With Eosinophilia MPE Emp Eosinophils, Malignant Proliferation Of Chronic Myeloproliferative Disorder With Eosinophilia Chronic Myeloproliferative Disease, Unclassifiable Cmpd-U Undifferentiated Myeloproliferative Disease Myeloproliferative Disorder Chronic With Eosinophilia Malignant Proliferation Of Eosinophils Myeloproliferative Neoplasm, Unclassifiable
Autosomal Recessive Cerebellar Ataxia	Arca
Lig4 Syndrome	Dna Ligase Iv Deficiency Ligase 4 Syndrome LIG4S
Xeroderma Pigmentosum, Variant Type	Xeroderma Pigmentosum XPV Xeroderma Pigmentosum Variant Type Xeroderma Pigmentosum With Normal Dna Repair Rates Photosensitivity With Defective Dna Synthesis Xp De Sanctis-Cacchione Syndrome Desanctis-Cacchione Syndrome Xeroderma Pigmentosa Xerodermic Idiocy Xeroderma Pigmentosum Variant Xp - [Xeroderma Pigmentosum] Atrophoderma Pigmentosum
Seckel Syndrome 4	SCKL4 Seckel Syndrome, Type 4
Ovarian Cancer	Ovarian Carcinoma Ovarian Neoplasm Malignant Tumour Of Ovary Cancer Of The Ovary Epithelial Ovarian Cancer Neoplasm Of Ovary Ovarian Neoplasms Ovarian Cancers Malignant Neoplasm Of Ovary Primary Malignant Neoplasm Of Ovary Ovarian Cancer, Somatic Malignant Ovarian Tumor Ovary Neoplasm Primary Ovarian Cancer Tumor Of The Ovary Malignant Neoplasm Of The Ovary Malignant Tumor Of The Ovary Ovarian Malignant Tumor OC Ovarian Carcinomas Cancer, Ovarian Cancer Of Ovary Ovary Cancer Ca Ovary
Nijmegen Breakage Syndrome	Berlin Breakage Syndrome NBS Microcephaly, Normal Intelligence And Immunodeficiency Ataxia-Telangiectasia Variant Ataxia-Telangiectasia Variant V1 Seemanova Syndrome Ii Immunodeficiency-Microcephaly-Chromosomal Instability Syndrome Seemanova Syndrome Type 2 At-V1 Microcephaly With Normal Intelligence, Immunodeficiency, And Lymphoreticular Malignancies Nonsyndromal Microcephaly, Autosomal Recessive, With Normal Intelligence Immunodeficiency, Microcephaly, And Chromosomal Instability Microcephaly-Immunodeficiency-Lymphoreticuloma Syndrome Microcephaly Immunodeficiency Lymphoreticuloma Microcephaly With Normal Intelligence Immunodeficiency And Lymphoreticular Malignancies Nonsyndromal Microcephaly Autosomal Recessive With Normal Intelligence Seemanova Syndrome 2 Ataxia-Telangiectasia Variant 1 Seemanova Syndrome At V1 Ataxia-Telangiectasia, Variant 1 Microcephaly-Immunodeficiency-Lymphoid Malignancy Syndrome V-At Ataxia Telangiectasia Variant V1
Hereditary Ataxia	Sca Spinocerebellar Ataxia Ataxias Hereditary Ataxias, Hereditary
Seckel Syndrome	Microcephalic Primordial Dwarfism Bird-Headed Dwarfism Harper'S Syndrome Virchow-Seckel Dwarfism Nanocephalic Dwarfism Sckl Seckel-Type Dwarfism
Cerebellar Disease	Cerebellar Diseases Cerebellar Dysfunction Cerebellar Abnormality Cerebellar Disorders
Primary Hyperoxaluria	Hyperoxaluria Hyperoxaluria, Primary Oxalosis Primary Oxalosis Congenital Oxaluria D-Glycerate Dehydrogenase Deficiency Glyceric Aciduria Glycolic Aciduria Hepatic Agt Deficiency Oxaluria, Primary Peroxisomal Alanine:Glyoxylate Aminotransferase Deficiency Primary Oxaluria Hyperoxaluria Primary Primary Hyperoxaluria Type 2 Primary Hyperoxaluria, Type I
Pancreatic Cancer	Pancreatic Carcinoma Carcinoma Of Pancreas Familial Pancreatic Carcinoma Pancreatic Neoplasm Pancreatic Carcinoma, Familial Malignant Neoplasm Of Pancreas Pancreatic Acinar Carcinoma Pancreatic Tumor Familial Pancreatic Cancer Neoplasm Of The Pancreas Cancer Of The Pancreas Pancreatic Carcinoma, Somatic Pancreatic Cancer, Somatic Ca Body Of Pancreas Ca Head Of Pancreas Ca Tail Of Pancreas Malignant Neoplasm Of Body Of Pancreas Malignant Neoplasm Of Head Of Pancreas Malignant Neoplasm Of Tail Of Pancreas Pancreas Neoplasm Exocrine Cancer Exocrine Pancreas Carcinoma Hereditary Pancreatic Cancer Hereditary Pancreatic Carcinoma PNCA Pancreatic Cancer, Susceptibility To Carcinoma Of Head Of Pancreas Pancreatic Neoplasms Pancreatic Tumors Cancer, Pancreatic Cancer Of Pancreas Mixed Islet Cell With Exocrine Carcinoma Of Unspecified Site
Hereditary Breast Ovarian Cancer Syndrome	Hereditary Breast And Ovarian Cancer Syndrome Brca1- And Brca2-Associated Hereditary Breast And Ovarian Cancer Breast And/Or Ovarian Cancer Breast And Ovarian Cancer Syndrome Hboc Syndrome Hereditary Breast And Ovarian Cancer Brca1- Brca2-Associated Hboc
Aplastic Anemia	Aplastic Anemia, Susceptibility To Anemia Aplastic Idiopathic Aplastic Anemia Secondary Aplastic Anemia Idiopathic Bone Marrow Failure Aplastic Anemia Idiopathic AA Anemia, Aplastic Aplastic Anemia, Idiopathic Erythroid Aplasia Aa - [Aplastic Anaemia] Haematopoietic Aplasia Aleukia Haemorrhagica Anaemia Due To Decreased Red Cell Production Aplasia Bone Marrow Aplastic Bone Marrow Hypoplastic Anaemia Nos Myeloid Bone Marrow Aplasia Pancytopenia Panhaematopenia Hypoproliferative Anaemia Medullary Hypoplasia Red Blood Cells Hypoplastic Anaemia Panmyelophthisis Panhemocytopenia Refractive Hypoproliferative Anaemia Toxic Anaemia Toxic Aplastic Anaemia Aplastic Anaemia Due To Toxic Cause Idiopathic Aplastic Anaemia Nos
Fanconi Anemia, Complementation Group A	Fanconi Anemia Fanconi Pancytopenia Fanconi Anemia Complementation Group A FANCA Fa Fanconi Panmyelopathy Fanconi'S Anemia Fanconi Anaemia Fanconi'S Anaemia Fanconi Hypoplastic Anemia Estren-Dameshek Variant Of Fanconi Anemia Estren-Dameshek Variant Of Fanconi Pancytopenia Fanconi Anemia Estren-Dameshek Variant Fanconis Anemia
Bone Osteosarcoma	Osteosarcoma Of Bone Primary Osteosarcoma Of Bone
Dyskeratosis Congenita	Dyskeratosis Congenita Autosomal Dominant Dc Dkc Zinsser-Engman-Cole Syndrome Dyskeratosis Congenita, Autosomal Dominant Autosomal Dominant Dyskeratosis Congenita Dkca Dyskeratosis Congenita Scoggins Type Zinsser-Cole-Engman Syndrome X-Linked Dyskeratosis Congenita Hoyeraal-Hreidarsson Syndrome
Primary Autosomal Recessive Microcephaly	Autosomal Recessive Primary Microcephaly Mcph True Microcephaly Microcephalia Vera Microcephaly Vera Microcephaly Primary Hereditary Microcephaly, Primary, Autosomal Recessive Primary Microcephaly
Congenital Nervous System Abnormality	Congenital Neurologic Anomaly Congenital Nervous System Disorder

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS14915	TP53BP1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	TP53BP1	VGNC	VGNC:36232
Mus musculus	TP53BP1	MGD	MGI:1351320
Rattus norvegicus	TP53BP1	RGD	RGD:1308039
Canis familiaris	TP53BP1	VGNC	VGNC:47720
Felis catus	TP53BP1	VGNC	VGNC:66461
Macaca mulatta	TP53BP1	VGNC	VGNC:78628
Others	TP53BP1	NCBI