53BP1 Antibody

Cat. No.: HY-P80001: FAQs
Data Sheet SDS COA User Guide for Antibodies

53BP1 Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 214 kDa, targeting to TP53BP1. It can be used for WB,ICC/IF,IHC-P,FC assays with tag free, in the background of Human, Mouse, Rat.

For research use only. We do not sell to patients.

Size	Price	Stock	Quantity
Free Sample		Apply now
10 μL	$92	In-stock	Estimated Time of Arrival: December 31
50 μL	$245	In-stock	Estimated Time of Arrival: December 31
100 μL	$400	In-stock	Estimated Time of Arrival: December 31
250 μL		Get quote

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Biological Activity
Technical Parameters
Properties
Documentation

Description	53BP1 Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 214 kDa, targeting to TP53BP1. It can be used for WB,ICC/IF,IHC-P,FC assays with tag free, in the background of Human, Mouse, Rat.
Background	TP53BP1: This gene encodes a protein that functions in the DNA double-strand break repair pathway choice, promoting non-homologous end joining (NHEJ) pathways, and limiting homologous recombination. This protein plays multiple roles in the DNA damage response, including promoting checkpoint signaling following DNA damage, acting as a scaffold for recruitment of DNA damage response proteins to damaged chromatin, and promoting NHEJ pathways by limiting end resection following a double-strand break. These roles are also important during V(D)J recombination, class switch recombination and at unprotected telomeres. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2017]
Tag	Free
Molecular Weight	Predicted band size: 214 kDa
Purity	Protein A affinity purified.
Subcellular Location	Nucleus. Chromosome.
Conjugation	Non-conjugated
Research Field	Epigenetics and Nuclear Signaling
Product Categories	Primary Antibody; Recombinant Rabbit Monoclonal Antibody
Host	Rabbit
Reactivity	Human, Mouse, Rat
SwissProt ID	SwissProt: Q12888 Human;SwissProt: P70399 Mouse;Entrez Gene: 296099 Rat
Dilution Ratio	WB: 1:500-1:1,000 ;ICC/IF: 1:100-1:500 ;IHC-P: 1:50-1:200 ;FC: 1:50-1:100
Application	WB, ICC/IF, IHC-P, FC
Appearance	Liquid
Formulation	Supplied in 1*TBS (pH7.4), 0.05% BSA and 40% Glycerol. Preservative: 0.05% Sodium Azide.
Storage & Stability	Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping	Shipping with blue ice.
Isotype	IgG
Immunogen	Synthetic peptide corresponding to Human 53BP1.AA range:1-50.
Documentation	Select Batch: Data Sheet (234 KB) SDS (251 KB) COA (205 KB) User Guide for Antibodies (1077 KB)

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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53BP1 Antibody

Biological Activity

Technical Parameters

Properties

Documentation

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