p53 Antibody

p53 Antibody is a non-conjugated and Rabbit origined polyclonal antibody about 44 kDa, targeting to p53 tumor protein. It can be used for WB,IHC,IF, ELISA assays in the background of Human, Mouse, Rat, Monkey.

p53: This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277). [provided by RefSeq, Dec 2016]

7157

Predicted band size: 44 kDa

Non-conjugated

Cell Biology

Primary Antibody; Rabbit Polyclonal Antibody

Rabbit

Human, Mouse, Rat, Monkey

P04637

WB: 1:500-1:1,000 ;IHC: 1:50-1:100 ;IF: 1:50-1:200 ;ELISA: 1:10,000

WB, IHC, IF, ELISA

Liquid

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping with blue ice.

IgG

Synthetic peptide corresponding to Human p53.AA range:10-59.