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57116

" within the MedChemExpress (MCE) catalog. Here are the results you might be looking for.

By Targets:	5-HT Receptor (2) Antibiotic (2) Bacterial (3) CXCR (1) Endonuclease (1) Histamine Receptor (1) Influenza Virus (1) Integrin (1) MicroRNA (12)
By Research Areas:	Cancer (14) Infection (5) Inflammation/Immunology (2) Neurological Disease (2)
Oligonucleotides:	miRNA mimics (3) miRNA antagomirs (3) miRNA agomirs (3) MicroRNAs (12) miRNA inhibitors (3)

Inhibitors & Agonists

Inhibitory Antibodies

Antibodies

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-177555

AV5116	Influenza Virus Endonuclease	Infection
AV5116 is a cap-dependent endonuclease inhibitor (CENI) that binds to the active site of the cap-dependent endonuclease (CEN) located in the N-terminal domain of the polymerase acidic. AV5116 exhibits potent inhibitory activity against influenza viruses (influenza A, B, and C viruses). AV5116 can be used for the study of influenza virus infections .

HY-109544

Repirinast MY-5116	Histamine Receptor	Inflammation/Immunology
Repirinast (MY-5116) is an orally active anti-allergic agent. Repirinast inhibits histamine release. Repirinast can be used in the research of bronchial asthma .

HY-A0147A

Grepafloxacin hydrochloride OPC-17116 hydrochloride; dl-Grepafloxacin hydrochloride	Antibiotic Bacterial	Infection
Grepafloxacin (OPC-17116) hydrochloride is an oral actively fluoroquinolone antibiotic with potent activity against community-acquired respiratory pathogens including Streptococcus pneumonia. Grepafloxacin hydrochloride has high tissue penetration and a promising pharmacodynamic profile .

HY-144347

HF51116	CXCR	Infection Cancer
HF51116 is a potent antagonist of CXCR4. HF51116 strongly antagonizes SDF-1α-induced cell migration, calcium mobilization, and CXCR4 internalization. HF51116 inhibits HIV-1 infection via CXCR4. HF51116 has the potential for the research of HIV-1 infection, hematopoietic stem cell mobilization, and cancer metastasis .

HY-18714

BRD7116	Others	Cancer
BRD7116 is a cell-non-autonomous inhibitor of leukemic stem cells (LSCs). BRD7116, without directly contacting LSCs, can inhibit LSCs merely by altering the microenvironment. BRD7116 also has any cell-autonomous effects on LSCs and induces transcriptional changes consistent with myeloid differentiation. BRD7116 can be used for the study of leukemia .

HY-A0147

Grepafloxacin OPC-17116; dl-Grepafloxacin	Antibiotic Bacterial	Infection
Grepafloxacin (OPC-17116) is an oral actively fluoroquinolone antibiotic with potent activity against community-acquired respiratory pathogens including Streptococcus pneumonia. Grepafloxacin has high tissue penetration and a promising pharmacodynamic profile .

HY-123747A

*SC-53116* hydrochloride**	5-HT Receptor	Neurological Disease
SC-53116 hydrochloride is a selective 5-HT4 receptor agonist with EC₅₀ at 23 nM .

HY-123747

SC-53116	5-HT Receptor	Neurological Disease
SC-53116 is a selective 5-HT4 receptor agonist with EC₅₀ at 23 nM .

HY-R03261

*mmu-miR-5116* mimic**	MicroRNA	Cancer
mmu-miR-5116 mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

mmu-miR-5116 mimic mmu-miR-5116 mimic

HY-R03942

*mmu-miR-7116-5p mimic*	MicroRNA	Cancer
mmu-miR-7116-5p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

mmu-miR-7116-5p mimic mmu-miR-7116-5p mimic

HY-RI03942A

*mmu-miR-7116-5p antagomir*	MicroRNA	Cancer
mmu-miR-7116-5p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

mmu-miR-7116-5p antagomir mmu-miR-7116-5p antagomir

HY-RI03941

*mmu-miR-7116-3p inhibitor*	MicroRNA	Cancer
mmu-miR-7116-3p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

mmu-miR-7116-3p inhibitor mmu-miR-7116-3p inhibitor

HY-RI03942

*mmu-miR-7116-5p inhibitor*	MicroRNA	Cancer
mmu-miR-7116-5p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

mmu-miR-7116-5p inhibitor mmu-miR-7116-5p inhibitor

HY-RI03941A

*mmu-miR-7116-3p antagomir*	MicroRNA	Cancer
mmu-miR-7116-3p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

mmu-miR-7116-3p antagomir mmu-miR-7116-3p antagomir

HY-117488

(S)-Grepafloxacin (S)-OPC-17116; (S)-dl-Grepafloxacin	Bacterial	Infection
(S)-Grepafloxacin ((S)-OPC-17116) is the S-enantiomer of Grepafloxacin (HY-A0147) .

HY-R03261A

*mmu-miR-5116* agomir**	MicroRNA	Cancer
mmu-miR-5116 agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

mmu-miR-5116 agomir mmu-miR-5116 agomir

HY-RI03261

*mmu-miR-5116* inhibitor**	MicroRNA	Cancer
mmu-miR-5116 inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

mmu-miR-5116 inhibitor mmu-miR-5116 inhibitor

HY-RI03261A

*mmu-miR-5116* antagomir**	MicroRNA	Cancer
mmu-miR-5116 antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

mmu-miR-5116 antagomir mmu-miR-5116 antagomir

HY-R03941

*mmu-miR-7116-3p mimic*	MicroRNA	Cancer
mmu-miR-7116-3p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

mmu-miR-7116-3p mimic mmu-miR-7116-3p mimic

HY-R03942A

*mmu-miR-7116-5p agomir*	MicroRNA	Cancer
mmu-miR-7116-5p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

mmu-miR-7116-5p agomir mmu-miR-7116-5p agomir

HY-R03941A

*mmu-miR-7116-3p agomir*	MicroRNA	Cancer
mmu-miR-7116-3p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

mmu-miR-7116-3p agomir mmu-miR-7116-3p agomir

HY-P991825

*Anti-Mouse CD18 Antibody (C71/16)*	Integrin	Inflammation/Immunology
Anti-Mouse CD18 Antibody (C71/16) reacts with an epitope on mouse CD18. CD18 is the Integrin β2 chain. Recommend Isotype Controls: Rat IgG1 kappa, Isotype Control (HY-P99979) .

*Anti-Mouse CD18 Antibody (C71/16)*	Integrin	Inflammation/Immunology
Anti-Mouse CD18 Antibody (C71/16) reacts with an epitope on mouse CD18. CD18 is the Integrin β2 chain. Recommend Isotype Controls: Rat IgG1 kappa, Isotype Control (HY-P99979) .

Host:	Mouse (7)
Reactivity:	Human (7) Rat (3) Mouse (3) Dog (1) Pig (1)
Application:	IHC-P (4) ICC/IF (2) WB (1) FC (4) ELISA (4)
Isotype:	IgG1 (5) IgG2b (1)
Conjugation:	Non-conjugated (7)
Clonality:	Monoclonal (5)
Modification:	Unmodified (5)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P86019

	COX2 Antibody (YA5711)	IHC-P, ELISA	Human
	COX2 Antibody (YA5711) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to COX2.

HY-P87428

	CLEC10A/CD301 Antibody (YA7116)	FC, ELISA	Human
	CLEC10A/CD301 Antibody (YA7116) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CLEC10A/CD301.

HY-P88637

	DTNB (Dystrobrevin beta) Antibody (YA8321) MGC17163; MGC57126	IHC-P, ICC/IF, FC	Human, Mouse, Rat
	DTNB (Dystrobrevin beta) Antibody (YA8321) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to DTNB (Dystrobrevin beta).

HY-P87428A

	CLEC10A/CD301 Antibody (YA7116)(PBS only)	FC, ELISA	Human
	CLEC10A/CD301 Antibody (YA7116) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CLEC10A/CD301.

HY-P88637A

	DTNB (Dystrobrevin beta) Antibody (YA8321)(PBS only) MGC17163; MGC57126	IHC-P, ICC/IF, FC	Human, Mouse, Rat
	DTNB (Dystrobrevin beta) Antibody (YA8321) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to DTNB (Dystrobrevin beta).

HY-P85424

	Cyclin H Antibody (YA5116) CCNH; Cyclin-H; MO15-associated protein; p34; p37	WB	Human, Mouse, Rat, Dog, Pig
	Cyclin H Antibody (YA5116) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to Cyclin H.

HY-P86024

	Mucin 1 Antibody (YA5716) Mucin-1; MUC-1; Breast carcinoma-associated antigen DF3; Carcinoma-associated mucin; Episialin; H23AG; Krebs von den Lungen-6; KL-6; PEMT; Peanut-reactive urinary mucin; PUM; Polymorphic epithelial mucin; PEM; Tumor-associated epithelial membrane antigen; EMA; Tumor-associated mucin; CD antigen CD227; [Cleaved into: Mucin-1 subunit alpha; MUC1-NT; MUC1-alpha; Mucin-1 subunit beta; MUC1-beta; MUC1-CT; ]	IHC-P, ELISA	Human
	Mucin 1 Antibody (YA5716) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Mucin 1.

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Cat. No.	Product Name		Classification

HY-R03261

*mmu-miR-5116* mimic**		MicroRNAs miRNA mimics
mmu-miR-5116 mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

HY-R03942

*mmu-miR-7116-5p mimic*		MicroRNAs miRNA mimics
mmu-miR-7116-5p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

HY-RI03942A

*mmu-miR-7116-5p antagomir*		MicroRNAs miRNA antagomirs
mmu-miR-7116-5p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-RI03941

*mmu-miR-7116-3p inhibitor*		MicroRNAs miRNA inhibitors
mmu-miR-7116-3p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

HY-RI03942

*mmu-miR-7116-5p inhibitor*		MicroRNAs miRNA inhibitors
mmu-miR-7116-5p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

HY-RI03941A

*mmu-miR-7116-3p antagomir*		MicroRNAs miRNA antagomirs
mmu-miR-7116-3p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-R03261A

*mmu-miR-5116* agomir**		MicroRNAs miRNA agomirs
mmu-miR-5116 agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-RI03261

*mmu-miR-5116* inhibitor**		MicroRNAs miRNA inhibitors
mmu-miR-5116 inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

HY-RI03261A

*mmu-miR-5116* antagomir**		MicroRNAs miRNA antagomirs
mmu-miR-5116 antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-R03941

*mmu-miR-7116-3p mimic*		MicroRNAs miRNA mimics
mmu-miR-7116-3p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

HY-R03942A

*mmu-miR-7116-5p agomir*		MicroRNAs miRNA agomirs
mmu-miR-7116-5p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-R03941A

*mmu-miR-7116-3p agomir*		MicroRNAs miRNA agomirs
mmu-miR-7116-3p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

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