2177311-29-2
Chemical Structure
HF51116
- CAS No.: 2177311-29-2
- Formula:C29H46N8O
- Molecular Weight:522.73
IUPAC Name: (S)-N-(4-(((3-(cyclohexylamino)propyl)amino)methyl)benzyl)-5-guanidino-2-((pyridin-2-ylmethyl)amino)pentanamide
InChIKey: AMGQQWNQWHMPHG-MHZLTWQESA-N
SMILES: N=C(N)NCCC[C@H](NCC1=CC=CC=N1)C(NCC2=CC=C(C=C2)CNCCCNC3CCCCC3)=O
Biological Activity: HF51116 is a potent antagonist of CXCR4. HF51116 strongly antagonizes SDF-1α-induced cell migration, calcium mobilization, and CXCR4 internalization. HF51116 inhibits HIV-1 infection via CXCR4. HF51116 has the potential for the research of HIV-1 infection, hematopoietic stem cell mobilization, and cancer metastasis[1].
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HF51116 | HF51116 is a potent antagonist of CXCR4. HF51116 strongly antagonizes SDF-1α-induced cell migration, calcium mobilization, and CXCR4 internalization. HF51116 inhibits HIV-1 infection via CXCR4. HF51116 has the potential for the research of HIV-1 infection, hematopoietic stem cell mobilization, and cancer metastasis. | |||||||||||||||||||||
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Keywords
