BRME1 - break repair meiotic recombinase recruitment factor 1 Gene

Also Known as MEIOK21; C19orf57

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 79173

Summary

Predicted to enable damaged DNA binding activity. Predicted to be involved in meiosis I; protein localization to site of double-strand break; and spermatogenesis. Predicted to be located in chromosome. Predicted to be active in site of double-strand break. [provided by Alliance of Genome Resources, Apr 2025]
Broad expression in testis (RPKM 4.2), duodenum (RPKM 1.4) and 17 other tissues.

BRME1 Products (11)

mRNA Protein Name
NM_001345843.2 NP_001332772.2 break repair meiotic recombinase recruitment factor 1 isoform 1
NM_001345844.2 NP_001332773.2 break repair meiotic recombinase recruitment factor 1 isoform 3
NM_001345846.2 NP_001332775.1 break repair meiotic recombinase recruitment factor 1 isoform 4
NM_001345847.2 NP_001332776.1 break repair meiotic recombinase recruitment factor 1 isoform 5
NM_001345848.2 NP_001332777.2 break repair meiotic recombinase recruitment factor 1 isoform 6
NM_001393645.1 NP_001380574.1 break repair meiotic recombinase recruitment factor 1 isoform 1
NM_001393646.1 NP_001380575.1 break repair meiotic recombinase recruitment factor 1 isoform 1
NM_001393647.1 NP_001380576.1 break repair meiotic recombinase recruitment factor 1 isoform 4
NM_001393648.1 NP_001380577.1 break repair meiotic recombinase recruitment factor 1 isoform 7
NM_001393649.1 NP_001380578.1 break repair meiotic recombinase recruitment factor 1 isoform 8
NM_024323.5 NP_077299.3 break repair meiotic recombinase recruitment factor 1 isoform 3

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence Références Source
enables protein binding IPI
IPI: Inferred from physical interaction
16189514 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

BRME1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Références
Intra
BRME1 Q0VDD7 KRT40 Homo sapiens Q6A162
Y2H Prey Pooling
25416956
Intra
BRME1 Q0VDD7 KRT40 Homo sapiens Q6A162
Validated Y2H
25416956
Intra
BRME1 Q0VDD7 KRTAP10-9 Homo sapiens P60411
Validated Y2H
25416956
Intra
BRME1 Q0VDD7 KRTAP10-7 Homo sapiens P60409
Y2H Prey Pooling
25416956
Intra
BRME1 Q0VDD7 KRTAP10-7 Homo sapiens P60409
Y2H Array
25416956
Intra
BRME1 Q0VDD7 FAM9B Homo sapiens Q8IZU0
Validated Y2H
25416956
Intra
BRME1 Q0VDD7 RUNX1T1 Homo sapiens Q06455-4
Y2H Array
25416956
Intra
BRME1 Q0VDD7 RUNX1T1 Homo sapiens Q06455-4
Validated Y2H
25416956
Intra
BRME1 Q0VDD7 TSC22D3 Homo sapiens Q99576-3
Y2H Prey Pooling
25416956
Intra
BRME1 Q0VDD7 KRT38 Homo sapiens O76015
Y2H Prey Pooling
25416956
Intra
BRME1 Q0VDD7 KRT38 Homo sapiens O76015
Validated Y2H
25416956
Intra
BRME1 Q0VDD7 KIF1B Homo sapiens O60333-2
Validated Y2H
32814053
Intra
BRME1 Q0VDD7 KIF1B Homo sapiens O60333-2
Y2H Array
32814053
Intra
BRME1 Q0VDD7 KIF1B Homo sapiens O60333-2
Y2H Pooling
32814053
Intra
BRME1 Q0VDD7 HAUS3 Homo sapiens Q68CZ6
Validated Y2H
25416956
Intra
BRME1 Q0VDD7 HAUS3 Homo sapiens Q68CZ6
Y2H Prey Pooling
25416956
Intra
BRME1 Q0VDD7 PSMA6 Homo sapiens P60900
Y2H Array
25416956
Intra
BRME1 Q0VDD7 CTNNAL1 Homo sapiens Q9UBT7
Y2H Array
25416956
Intra
BRME1 Q0VDD7 TTR Homo sapiens P02766
Validated Y2H
32814053
Intra
BRME1 Q0VDD7 TTR Homo sapiens P02766
Y2H Array
32814053
Intra
BRME1 Q0VDD7 TTR Homo sapiens P02766
Y2H Pooling
32814053
Intra
BRME1 Q0VDD7 WFS1 Homo sapiens O76024
Y2H Pooling
32814053
Intra
BRME1 Q0VDD7 WFS1 Homo sapiens O76024
Validated Y2H
32814053
Intra
BRME1 Q0VDD7 WFS1 Homo sapiens O76024
Y2H Array
32814053
Intra
BRME1 Q0VDD7 TRIM23 Homo sapiens P36406
Validated Y2H
25416956
Intra
BRME1 Q0VDD7 TRIM23 Homo sapiens P36406
Y2H Array
25416956
Intra
BRME1 Q0VDD7 AIMP2 Homo sapiens Q13155
Validated Y2H
25416956
Intra
BRME1 Q0VDD7 AIMP2 Homo sapiens Q13155
Y2H Array
25416956
Intra
BRME1 Q0VDD7 AIMP2 Homo sapiens Q13155
Y2H
21516116
Intra
BRME1 Q0VDD7 HOMER1 Homo sapiens Q86YM7
Validated Y2H
25416956
Intra
BRME1 Q0VDD7 HOMER1 Homo sapiens Q86YM7
Y2H Array
25416956
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Nom du produit
Effect
Pureté
Rare Diseases
HY-RS01626 BRMS1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22408 Brms1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28932 Brms1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown