2. Gene
  3. HAUS3 - HAUS augmin like complex subunit 3 Gene

HAUS3 - HAUS augmin like complex subunit 3 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as IT1; dgt3; C4orf15

Gene ID: 79441 | Gene type: protein coding

About HAUS3

Cytogenetic location: 4p16.3 Genomic coordinates (GRCh38): 4:2,228,349-2,242,121 (from NCBI)

This gene has 5 transcripts (splice variants) and 192 orthologues. Ubiquitous expression in bone marrow (RPKM 19.8), lymph node (RPKM 8.7) and 24 other tissues.

Summary

This gene encodes a component of the HAUS augmin-like protein complex, which plays a key role in cytokinesis and mitosis. Disruption of the encoded protein causes mitotic defects resulting from fragmentation of centrosomes and microtubule destabilization. This gene shares its 5' exons with some transcripts from overlapping GeneID: 353497, which encodes a DNA polymerase. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]

HAUS3 Products(2)

mRNA Protein Name
NM_001303143.2 NP_001290072.1 HAUS augmin-like complex subunit 3
NM_024511.7 NP_078787.2 HAUS augmin-like complex subunit 3

HAUS3 Protein Structure

HAUS-augmin3

HAUS-augmin3: HAUS augmin-like complex subunit 3 (29 - 283)

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  • 603 a.a.
Protein Preferred Names Protein Names

HAUS augmin-like complex subunit 3

Related Diseases

Diseases Alias
Baritosis

Deposition Of Barium In The Lungs

Inhalation Of Barytes
Cystic Basal Cell Carcinoma

Skin Cystic Basal Cell Carcinoma
Micronodular Basal Cell Carcinoma

Skin Micronodular Basal Cell Carcinoma

Basal Cell Carcinoma, Micronodular
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS06015 HAUS3 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus HAUS3 VGNC VGNC:62756
Macaca mulatta HAUS3 VGNC VGNC:73252
Canis familiaris HAUS3 VGNC VGNC:41604
Rattus norvegicus HAUS3 RGD RGD:1591723
Mus musculus HAUS3 MGD MGI:2387633
Bos taurus HAUS3 VGNC VGNC:29759