SNAI1 - snail family transcriptional repressor 1 Gene

Also Known as SNA; SNAH; SNAIL; SLUGH2; SNAIL1; dJ710H13.1

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 6615

About SNAI1

Cytogenetic location: 20q13.13 Genomic coordinates (GRCh38): 20:49,982,980-49,988,886 (from NCBI)

This gene has 1 transcript (splice variant), 256 orthologues and 36 paralogues. Broad expression in gall bladder (RPKM 10.2), thyroid (RPKM 5.1) and 21 other tissues.

Summary

The Drosophila embryonic protein snail is a zinc finger transcriptional repressor which downregulates the expression of ectodermal genes within the mesoderm. The nuclear protein encoded by this gene is structurally similar to the Drosophila snail protein, and is also thought to be critical for mesoderm formation in the developing embryo. At least two variants of a similar processed pseudogene have been found on chromosome 2. [provided by RefSeq, Jul 2008]

SNAI1 Products (1)

mRNA	Protein	Name
NM_005985.4	NP_005976.2	zinc finger protein SNAI1

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	References	Source
enables DNA-binding transcription repressor activity, RNA polymerase II-specific	IDA IDA: Inferred from direct assay	11912130	GOA
enables E-box binding	IDA IDA: Inferred from direct assay	11912130	GOA
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding	IDA IDA: Inferred from direct assay	11912130	GOA
enables kinase binding	IPI IPI: Inferred from physical interaction	15448698	GOA
enables protein binding	IPI IPI: Inferred from physical interaction	15448698	GOA
enables sequence-specific double-stranded DNA binding	IDA IDA: Inferred from direct assay	28473536	GOA

Biological Process GO Annotation	Evidence	References	Source
involved in canonical Wnt signaling pathway	IMP IMP: Inferred from mutant phenotype	17072303	GOA
involved in epithelial to mesenchymal transition	IDA IDA: Inferred from direct assay	16096638	GOA
involved in negative regulation of DNA damage response, signal transduction by p53 class mediator	IMP IMP: Inferred from mutant phenotype	15314165	GOA
involved in negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage	IMP IMP: Inferred from mutant phenotype	15314165	GOA
involved in negative regulation of transcription by RNA polymerase II	IDA IDA: Inferred from direct assay	11912130	GOA
involved in negative regulation of transcription by RNA polymerase II	IMP IMP: Inferred from mutant phenotype	15314165	GOA
involved in negative regulation of vitamin D biosynthetic process	IDA IDA: Inferred from direct assay	19502595	GOA
involved in osteoblast differentiation	IEP IEP: Inferred from expression pattern	20128911	GOA
involved in positive regulation of DNA-templated transcription	IMP IMP: Inferred from mutant phenotype	20018240	GOA
involved in positive regulation of cell migration	IMP IMP: Inferred from mutant phenotype	15314165	GOA
involved in positive regulation of epithelial to mesenchymal transition	IMP IMP: Inferred from mutant phenotype	20018240	GOA
involved in regulation of bicellular tight junction assembly	IMP IMP: Inferred from mutant phenotype	15314165	GOA

Cellular Component GO Annotation	Evidence	References	Source
located in cytoplasm	IDA IDA: Inferred from direct assay	15448698	GOA
located in nucleus	IDA IDA: Inferred from direct assay	15448698	GOA
located in pericentric heterochromatin	IDA IDA: Inferred from direct assay	24239292	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

SNAI1 Protein Structure

zf-C2H2

zf-C2H2_6

zf-H2C2_2

0
100
200
264 a.a.

Protein Preferred Names	Protein Names
zinc finger protein SNAI1	protein sna

SNAI1 Protein-protein interaction Information

Type	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	References
Intra	SNAI1	O95863	KRT40	Homo sapiens	Q6A162	Y2H Array	31515488
Intra	SNAI1	O95863	MID2	Homo sapiens	Q9UJV3-2	Y2H Prey Pooling	25416956
Intra	SNAI1	O95863	MID2	Homo sapiens	Q9UJV3-2	Validated Y2H	25416956
Intra	SNAI1	O95863	FBXO11	Homo sapiens	Q86XK2	Anti Bait CoIP	25203322
Intra	SNAI1	O95863	FBXO11	Homo sapiens	Q86XK2	Anti Tag CoIP	25203322
Intra	SNAI1	O95863	KRTAP1-1	Homo sapiens	Q07627	Y2H Prey Pooling	32296183
Intra	SNAI1	O95863	KRTAP1-1	Homo sapiens	Q07627	Validated Y2H	32296183
Intra	SNAI1	O95863	KRTAP1-1	Homo sapiens	Q07627	Y2H Array	32296183
Intra	SNAI1	O95863	SPSB1	Homo sapiens	Q96BD6	Anti Tag CoIP	25203322
Intra	SNAI1	O95863	ACTN3	Homo sapiens	Q08043	Validated Y2H	32296183
Intra	SNAI1	O95863	ACTN3	Homo sapiens	Q08043	Y2H Prey Pooling	32296183
Intra	SNAI1	O95863	ACTN3	Homo sapiens	Q08043	Y2H Array	32296183
Cross	SNAI1	O95863	Crebbp	Mus musculus	P45481	Anti Tag CoIP	25314079
Intra	SNAI1	O95863	HDAC2	Homo sapiens	Q92769	Anti Tag CoIP	25314079
Intra	SNAI1	O95863	HDAC2	Homo sapiens	Q92769	Deacetylase Assay	25314079
Intra	SNAI1	O95863	HDAC1	Homo sapiens	Q13547	Deacetylase Assay	25314079
Intra	SNAI1	O95863	HDAC1	Homo sapiens	Q13547	Anti Tag CoIP	25314079
Intra	SNAI1	O95863	HDAC1	Homo sapiens	Q13547	Pull Down	20562920
Intra	SNAI1	O95863	BTRC	Homo sapiens	Q9Y297	Anti Bait CoIP	19411070
Intra	SNAI1	O95863	BTRC	Homo sapiens	Q9Y297	Anti Tag CoIP	20389281
Intra	SNAI1	O95863	PARP1	Homo sapiens	P09874	Anti Bait CoIP	21577210
Intra	SNAI1	O95863	PARP1	Homo sapiens	P09874	Confocal	21577210
Intra	SNAI1	O95863	TRAF2	Homo sapiens	Q12933	Y2H Array	32296183
Intra	SNAI1	O95863	TRAF2	Homo sapiens	Q12933	Y2H Prey Pooling	32296183
Intra	SNAI1	O95863	TRAF2	Homo sapiens	Q12933	Validated Y2H	32296183
Intra	SNAI1	O95863	PFDN5	Homo sapiens	Q99471	Y2H Prey Pooling	32296183
Intra	SNAI1	O95863	PFDN5	Homo sapiens	Q99471	Validated Y2H	32296183
Intra	SNAI1	O95863	PFDN5	Homo sapiens	Q99471	Y2H Array	32296183
Intra	SNAI1	O95863	TP53	Homo sapiens	P04637	Anti Tag CoIP	20385133
Intra	SNAI1	O95863	TP53	Homo sapiens	P04637	Anti Bait CoIP	20385133
Intra	SNAI1	O95863	EXOSC8	Homo sapiens	Q96B26	Validated Y2H	32296183
Intra	SNAI1	O95863	EXOSC8	Homo sapiens	Q96B26	Y2H Array	32296183
Intra	SNAI1	O95863	EXOSC8	Homo sapiens	Q96B26	Y2H Prey Pooling	32296183
Intra	SNAI1	O95863	GSK3B	Homo sapiens	P49841	Anti Bait CoIP	19411070
Intra	SNAI1	O95863	GSK3B	Homo sapiens	P49841	Anti Tag CoIP	20389281
Intra	SNAI1	O95863	COG6	Homo sapiens	Q9Y2V7	Y2H Prey Pooling	32296183
Intra	SNAI1	O95863	COG6	Homo sapiens	Q9Y2V7	Validated Y2H	32296183
Intra	SNAI1	O95863	COG6	Homo sapiens	Q9Y2V7	Y2H Array	32296183
Intra	SNAI1	O95863	EP300	Homo sapiens	Q09472	Acetylase Assay	25314079
Intra	SNAI1	O95863	EP300	Homo sapiens	Q09472	Anti Bait CoIP	25314079
Intra	SNAI1	O95863	GOLGA6L9	Homo sapiens	A6NEM1	Y2H Array	32296183
Intra	SNAI1	O95863	GOLGA6L9	Homo sapiens	A6NEM1	Y2H Prey Pooling	32296183
Intra	SNAI1	O95863	FBXL14	Homo sapiens	Q8N1E6	Anti Tag CoIP	25203322
Intra	SNAI1	O95863	FHL2	Homo sapiens	Q14192	Validated Y2H	32296183
Intra	SNAI1	O95863	KDM1A	Homo sapiens	O60341	Anti Bait CoIP	20389281
Intra	SNAI1	O95863	KDM1A	Homo sapiens	O60341	Anti Tag CoIP	20389281
Intra	SNAI1	O95863	GLMN	Homo sapiens	Q92990	Validated Y2H	32296183
Intra	SNAI1	O95863	GLMN	Homo sapiens	Q92990	Y2H Prey Pooling	32296183
Intra	SNAI1	O95863	GLMN	Homo sapiens	Q92990	Y2H Array	32296183
Intra	SNAI1	O95863	RELA	Homo sapiens	Q04206	CH-IP	25314079
Intra	SNAI1	O95863	TRIM23	Homo sapiens	P36406	Y2H Array	32296183
Intra	SNAI1	O95863	TRIM23	Homo sapiens	P36406	Y2H Prey Pooling	32296183
Intra	SNAI1	O95863	TRIM23	Homo sapiens	P36406	Y2H Prey Pooling	25416956
Intra	SNAI1	O95863	TRIM23	Homo sapiens	P36406	Validated Y2H	32296183
Intra	SNAI1	O95863	TRIP6	Homo sapiens	Q15654	Y2H Array	32296183
Intra	SNAI1	O95863	TRIP6	Homo sapiens	Q15654	Y2H Prey Pooling	32296183
Intra	SNAI1	O95863	TRIP6	Homo sapiens	Q15654	Validated Y2H	32296183
Intra	SNAI1	O95863	MTUS2	Homo sapiens	Q5JR59	Y2H Prey Pooling	25416956
Intra	SNAI1	O95863	MTUS2	Homo sapiens	Q5JR59	Validated Y2H	25416956
Intra	SNAI1	O95863	MTUS2	Homo sapiens	Q5JR59	Y2H Array	25416956
Intra	SNAI1	O95863	EFHC1	Homo sapiens	Q5JVL4	Validated Y2H	32296183
Intra	SNAI1	O95863	ACTN2	Homo sapiens	P35609	Y2H Array	31515488
Intra	SNAI1	O95863	ACTN2	Homo sapiens	P35609	Y2H Prey Pooling	25416956
Intra	SNAI1	O95863	ACTN2	Homo sapiens	P35609	Y2H Prey Pooling	32296183
Intra	SNAI1	O95863	ACTN2	Homo sapiens	P35609	Validated Y2H	32296183
Intra	SNAI1	O95863	ACTN2	Homo sapiens	P35609	Y2H Array	32296183
Intra	SNAI1	O95863	TRIM5	Homo sapiens	Q9C035	Anti Tag CoIP	25203322
Intra	SNAI1	O95863	NOTCH2NLA	Homo sapiens	Q7Z3S9	Y2H Array	25416956
Intra	SNAI1	O95863	NOTCH2NLA	Homo sapiens	Q7Z3S9	Validated Y2H	25416956
Intra	SNAI1	O95863	NOTCH2NLA	Homo sapiens	Q7Z3S9	Y2H Array	31515488
Intra	SNAI1	O95863	KRT31	Homo sapiens	Q15323	Y2H Prey Pooling	25416956
Intra	SNAI1	O95863	AJUBA	Homo sapiens	Q96IF1	Anti Tag CoIP	25314079
Intra	SNAI1	O95863	AJUBA	Homo sapiens	Q96IF1	CH-IP	25314079

Cross: Cross-species interaction Intra: Intraspecies interaction

SNAI1 Antibodies

Cat. No.	Product Name	Application	Reactivity
HY-P81135	SNAI1 Antibody	WB, IHC-P, ICC/IF, ELISA	Human, Mouse, Monkey
HY-P83878	SNAI1 Antibody (YA3575)	WB, ELISA	Human
HY-P83878A	SNAI1 Antibody (YA3575)(PBS only)	WB, ELISA	Human
HY-P85372	SNAI1 Antibody (YA5064)	WB	Human

Related Diseases

Diseases	Alias
Adenomyosis	Endometriosis Of Uterus Endometriosis Interna Endometriosis Of Myometrium Endometriosis, Myometrium Uterine Adenomyosis Adenomyosis Uteri Internal Endometriosis
Cercarial Dermatitis	Swimmer'S Itch Cutaneous Schistosomiasis Sea Bather'S Eruption Clam-Digger'S Itch Rice-Paddy Itch Sea Bather'S Itch Sawah Itch Schistosomal Cercarial Dermatitis
Pancreatic Cancer	Pancreatic Carcinoma Carcinoma Of Pancreas Familial Pancreatic Carcinoma Pancreatic Neoplasm Pancreatic Carcinoma, Familial Malignant Neoplasm Of Pancreas Pancreatic Acinar Carcinoma Pancreatic Tumor Familial Pancreatic Cancer Neoplasm Of The Pancreas Cancer Of The Pancreas Pancreatic Carcinoma, Somatic Pancreatic Cancer, Somatic Ca Body Of Pancreas Ca Head Of Pancreas Ca Tail Of Pancreas Malignant Neoplasm Of Body Of Pancreas Malignant Neoplasm Of Head Of Pancreas Malignant Neoplasm Of Tail Of Pancreas Pancreas Neoplasm Exocrine Cancer Exocrine Pancreas Carcinoma Hereditary Pancreatic Cancer Hereditary Pancreatic Carcinoma PNCA Pancreatic Cancer, Susceptibility To Carcinoma Of Head Of Pancreas Pancreatic Neoplasms Pancreatic Tumors Cancer, Pancreatic Cancer Of Pancreas Mixed Islet Cell With Exocrine Carcinoma Of Unspecified Site
Colorectal Cancer	Colon Cancer Colorectal Carcinoma Colon Carcinoma Colorectal Cancer, Susceptibility To Carcinoma Of Colon CRC Colorectal Cancer With Chromosomal Instability, Somatic Colon Cancer, Somatic Colon Cancer, Susceptibility To Colonic Neoplasms Colorectal Neoplasms Colorectal Cancer, Somatic Colon Cancer, Advanced, Somatic Colonic Carcinoma Colorectal Carcinomas Colon Cancers Colorectal Cancers Cancer, Colorectal, Somatic Cancer, Colon Cancer, Colorectal, Susceptibility To Colorectal Neoplasm Colonic Neoplasm Malignant Tumor Of Colon
Central Pontine Myelinolysis	Myelinolysis, Central Pontine Osmotic Demyelination Syndrome Cpm Myelinolysis Central Pontine Central Pontine Myelinosis
Tongue Carcinoma	Tongue Cancer Malignant Neoplasm Of Tongue Tongue Neoplasms Tongue Neoplasm
Gastric Cancer	Stomach Cancer Gastric Carcinoma Stomach Carcinoma Gastric Cancer, Somatic Gastric Neoplasm Carcinoma Of Stomach Stomach Neoplasms Malignant Neoplasm Of Stomach Gastric Cancer Risk After H. Pylori Infection Cancer Of The Stomach Adult Stomach Cancer Adult Stomach Carcinoma GASC Gastric Cancer Intestinal Gastric Cancers Gastric Carcinomas Cancer, Gastric Stomach Neoplasm Malignant Neoplasm Of Body Of Stomach Malignant Tumor Of Lesser Curve Of Stomach Gastrocarcinoma Of Unspecified Site Leather Bottle Stomach Carcinoma Of Fundus Of Stomach Cancer Of Fundus Of Stomach Primary Malignant Neoplasm Of Body Of Stomach Cancer Of Body Of Stomach Primary Malignant Neoplasm Of Pyloric Antrum Pyloric Antrum Cancer Malignant Tumour Of Stomach
Ehlers-Danlos Syndrome	Eds Cutis Hyperelastica Elastic Skin Ehlers-Danlos Syndromes Ed Syndrome Ehlers Danlos Syndrome Ehlers Danlos Disease Eds - [Ehlers-Danlos Syndrome]
Urinary Schistosomiasis	Schistosoma Haematobium Infection Schistosoma Hematobium Infection Schistosomiasis Due To Schistosoma Haematobium Bladder Schistosomiasis Cystitis With Bilharziasis Schistosoma Haematobium Schistosoma Hematobium Infectious Disease Schistosomiasis Of Bladder Vesical Schistosomiasis Schistosomiasis Urinary Schistosomiasis Haematobia Genitourinary Bilharziasis Genitourinary Tract Schistosomiasis Schistosomiasis Due To Schistosoma Haematobium [Urinary Schistosomiasis] Haematochyluria In Schistosomiasis Infection Due To Schistosoma Matthei
Intestinal Schistosomiasis	Schistosomiasis Japonica Schistosomiasis Mansoni Katayama Fever Schistosoma Japonicum Infection Schistosoma Mansoni Infectious Disease Schistosomiasis
Endometrial Cancer	Endometrial Carcinoma Endometrial Neoplasm Malignant Neoplasm Of Endometrium Endometrioid Carcinoma Endometrial Neoplasms Carcinoma, Endometrioid Endometrial Cancer, Familial Endometrial Carcinoma, Somatic Endometrial Cancer, Susceptibility To Endometrial Ca Malignant Endometrial Neoplasm Neoplasm Of Endometrium Primary Malignant Neoplasm Of Endometrium Tumor Of Endometrium Carcinoma Of The Endometrium Endometrioid Carcinoma Of Female Reproductive System ENDMC Carcinoma Endometrioid Endometrial Cancers Cancer, Endometrial Uterine Corpus Cancer
Lung Cancer	Lung Carcinoma Non-Small Cell Lung Carcinoma Lung Cancer, Susceptibility To Lung Cancer, Protection Against Adenocarcinoma Of Lung, Somatic Adenocarcinoma Of Lung, Response To Tyrosine Kinase Inhibitor In Nonsmall Cell Lung Cancer Lung Neoplasm Carcinoma Of Lung Lung Non-Small Cell Carcinoma Non-Small Cell Lung Cancer Nsclc Lung Neoplasms Malignant Neoplasm Of Lung Alveolar Cell Carcinoma Nonsmall Cell Lung Cancer, Somatic Nonsmall Cell Lung Cancer, Response To Tyrosine Kinase Inhibitor In Nonsmall Cell Lung Cancer, Susceptibility To Lung Cancer, Somatic Lung Cancer, Resistance To Cancer Of Lung Cancer Of Bronchus Cancer Of The Lung Lung Malignancies Lung Malignant Tumors Malignant Lung Tumor Malignant Tumor Of Lung Pulmonary Cancer Pulmonary Carcinoma Pulmonary Neoplasms Respiratory Carcinoma LNCR Adenocarcinoma Of Lung Neoplasm Of Lung Cancer Lung Carcinoma Non-Small Cell Lung Carcinoma, Non-Small-Cell Lung Lung Cancers Lung Carcinomas Cancer, Lung Cancer, Lung, Non-Small Cell Primary Malignant Neoplasm Of Lung Bronchioloalveolar Adenocarcinoma
Craniosynostosis	Premature Closure Of Cranial Sutures Craniostenosis Craniosynostosis Syndrome Cso Craniosynostoses Congenital Ossification Of Cranial Sutures Congenital Ossification Of Sutures Of Skull Craniostosis Imperfect Fusion Of Skull Congenital Imperfect Closure Skull Imperfect Closure Skull Premature Closure Cranium Sutures Deficiency Of Craniofacial Axis
Breast Cancer	Breast Carcinoma Male Breast Cancer Breast Cancer, Familial Malignant Neoplasm Of Breast Breast Cancer, Susceptibility To Breast Cancer, Early-Onset Malignant Tumor Of Breast Carcinoma Of Male Breast Breast Cancer, Invasive Ductal Breast Cancer, Protection Against Breast Cancer, Somatic Breast Cancer, Male Breast Cancer, Lobular, Somatic Breast Tumor Mammary Cancer Mammary Tumor Malignant Neoplasm Of Male Breast Mammary Carcinoma Male Breast Carcinoma Familial Cancer Of Breast Invasive Ductal Breast Carcinoma Breast Cancer Susceptibility Breast Cancer, Male, Susceptibility To Breast Cancer, Early-Onset, Susceptibility To Malignant Tumor Of The Breast Mammary Neoplasm Primary Breast Cancer Neoplasm Of Male Breast Carcinoma Of Breast Breast Cancer In Men Familial Breast Cancer Cancer Of Breast BC Breast Cancer Familial Breast Cancer Familial Male Breast Cancer, Familial Male Breast Male Carcinoma Breast Neoplasms Breast Neoplasms, Male Mammary Tumors Mammary Carcinomas Cancer, Breast Cancer, Breast, Susceptibility Invasive Breast Ductal Carcinoma Breast Neoplasm Susceptibility To Breast Cancer Mammary Neoplasms Animal Mammary Neoplasms Primary Malignant Neoplasm Of Breast Infiltrating Ductal Carcinoma Of Breast Infiltrating Duct Carcinoma Of Unspecified Site Infiltrating Ductular Carcinoma Of Unspecified Site Invasive Breast Carcinoma Of No Special Type Microinvasive Carcinoma Of Breast Carcinoma With Apocrine Differentiation
Rhabdomyosarcoma
Breast Lobular Carcinoma	Cancer, Breast, Lobular Lobular Breast Carcinoma
Ovarian Cancer	Ovarian Carcinoma Ovarian Neoplasm Malignant Tumour Of Ovary Cancer Of The Ovary Epithelial Ovarian Cancer Neoplasm Of Ovary Ovarian Neoplasms Ovarian Cancers Malignant Neoplasm Of Ovary Primary Malignant Neoplasm Of Ovary Ovarian Cancer, Somatic Malignant Ovarian Tumor Ovary Neoplasm Primary Ovarian Cancer Tumor Of The Ovary Malignant Neoplasm Of The Ovary Malignant Tumor Of The Ovary Ovarian Malignant Tumor OC Ovarian Carcinomas Cancer, Ovarian Cancer Of Ovary Ovary Cancer Ca Ovary
Gallbladder Cancer	Gallbladder Carcinoma Gallbladder Neoplasm Malignant Neoplasm Of Gallbladder Malignant Tumour Of Gallbladder Gallbladder Ca Localized Malignant Gallbladder Neoplasm Malignant Tumor Of The Gallbladder Tumor Of The Gallbladder Cancer Of The Gallbladder Carcinoma Gallbladder Carcinoma Of Gallbladder Gallbladder Neoplasms Malignant Neoplasm Of Gallbladder Localized Cancer Of Gallbladder Primary Malignant Neoplasm Of Gallbladder
Ureteral Disease	Ureteral Diseases Ureteral Disorders Disorder Of Ureter
Hepatocellular Carcinoma	Liver Cancer Primary Liver Cancer HCC Hepatoma Malignant Neoplasm Of Liver Liver Neoplasms Cancer, Hepatocellular Liver Cell Carcinoma Lcc Hepatoblastoma, Somatic Hepatic Cancer Primary Malignant Neoplasm Of Liver Rare Tumor Of Liver And Intrahepatic Biliary Tract Hepatocellular Carcinoma, Somatic Hepatocellular Carcinoma, Childhood Type, Somatic Hepatocellular Cancer, Somatic Ca Liver - Primary Hepatic Neoplasm Malignant Hepato-Biliary Neoplasm Malignant Neoplasm Of Liver, Not Specified As Primary Or Secondary Malignant Neoplasm Of Liver, Primary Malignant Tumor Of Liver Neoplasm Of Liver Non-Resectable Primary Hepatic Malignant Neoplasm Resectable Malignant Neoplasm Of Liver Resectable Malignant Neoplasm Of The Liver Primary Liver Carcinoma Primary Malignant Liver Neoplasm Primary Cancer Of Liver Primary Tumor Of The Liver Rare Tumor Of Liver And Ibt Hepatocellular Cancer Neoplasm Of The Liver Carcinoma, Hepatocellular Hepatomas Liver Neoplasm Liver Carcinoma Liver And Intrahepatic Biliary Tract Carcinoma Malignant Hepatobiliary Neoplasm Adult Primary Hepatocellular Carcinoma Hepatoblastoma Carcinoma Of Liver Malignant Liver Tumour Malignant Hepatic Tumour
Breast Carcinoma In Situ	Carcinoma In Situ Of Breast Non-Infiltrating Carcinoma Of Breast Breast Cancer In Situ
Esophageal Cancer	Esophageal Carcinoma Carcinoma Of Esophagus Esophageal Squamous Cell Carcinoma, Somatic Esophageal Carcinoma, Somatic Esophagus Cancer Gastric Cardia Adenocarcinoma Esophageal Neoplasms Esophageal Cancer, Somatic Cancer Of Esophagus Cancer Of Oesophagus Carcinoma Of Oesophagus Ca Lower Third Oesophagus Ca Middle Third Oesophagus Malignant Neoplasm Of Distal Third Of Esophagus Malignant Neoplasm Of Lower Third Of Oesophagus Malignant Neoplasm Of Middle Third Of Oesophagus Malignant Neoplasm Of Proximal Third Of Esophagus Malignant Neoplasm Of Upper Third Esophagus Malignant Tumor Of Abdominal Esophagus Malignant Tumor Of Distal Third Of Esophagus Malignant Tumor Of Proximal Third Of Esophagus Malignant Tumor Of The Middle Third Of The Esophagus ESCR Aerodigestive Tract Cancer Escc Esophageal Squamous Cell Carcinoma Cancer, Esophageal Malignant Neoplasm Of Esophagus Squamous Cell Carcinoma Of Esophagus Malignant Neoplasm Of Middle Third Of Esophagus
Ductal Carcinoma In Situ	Noninfiltrating Intraductal Carcinoma
Tongue Disease	Abnormality Of The Tongue Tongue Diseases Tongue Disorders Disorder Of Tongue Glossopathy Unspecified Condition Of The Tongue
Tongue Squamous Cell Carcinoma	Squamous Cell Carcinoma Of Tongue
Renal Cell Carcinoma, Nonpapillary	Renal Cell Carcinoma RCC Nonpapillary Renal Cell Carcinoma Clear Cell Renal Cell Carcinoma Hypernephroma Adenocarcinoma Of Kidney Renal Carcinoma, Chromophobe, Somatic Clear Cell Carcinoma Of Kidney Clear-Cell Metastatic Renal Cell Carcinoma Clear Cell Renal Carcinoma Renal Cell Carcinoma, Somatic Conventional Renal Cell Carcinoma Conventional Renal Cell Carcinoma Renal Clear Cell Carcinoma Ccrcc Hereditary Clear Cell Renal Cell Carcinoma Carcinoma, Renal Cell Renal Cell Carcinoma, Clear Cell, Somatic Renal Cell Carcinoma, Clear Cell Clear Cell Kidney Carcinoma Clear Cell Rcc Cystic-Multilocular Variant Clear Cell Renal Cell Adenocarcinoma Hereditary Clear Cell Renal Cell Adenocarcinoma Common Renal Cell Carcinoma Crcc Renal Cell Carcinoma Non-Papillary Carcinoma Renal Cell Renal Cell Cancer Carcinoma, Renal Cell, Nonpapillary
Aortic Valve Disease 1	Aortic Valve Disease Bicuspid Aortic Valve Aortic Valve Disorder AOVD1 Bav Bicuspid Aortic Valve Disease Familial Bicuspid Aortic Valve Aortic Valve Calcification Aovd Aortic Valve, Bicuspid Aortic Valve, Calcification Of Aortic Stenosis, Calcific Familial Bav Calcific Aortic Stenosis Calcification Of Aortic Valve Abnormality Of The Aortic Valve Aortic Valve Disease, Type 1 Aortic Valve Disease 2 Bicommissural Aortic Valve
Head And Neck Cancer	Head And Neck Neoplasm Head And Neck Tumours Head/Neck Neoplasm Tumor Of Head And Neck Head And Neck Neoplasms Hnc Cancer, Head/Neck
Breast Adenocarcinoma	Mammary Adenocarcinoma Adenocarcinoma Of Breast
Interstitial Lung Disease 2	Idiopathic Pulmonary Fibrosis Ipf Fibrocystic Pulmonary Dysplasia Pulmonary Fibrosis, Idiopathic Pulmonary Fibrosis, Idiopathic, Susceptibility To Cryptogenic Fibrosing Alveolitis ILD2 Idiopathic Pulmonary Fibrosis, Familial Fibrosing Alveolitis, Cryptogenic Uip Fibrosing Alveolitis Interstitial Pneumonitis, Usual Familial Idiopathic Pulmonary Fibrosis Idiopathic Fibrosing Alveolitis, Chronic Form Usual Interstitial Pneumonia Fibrosing Alveolitis Cryptogenic Hamman-Rich Disease Idiopathic Pulmonary Fibrosis Familial Interstitial Pneumonitis Usual Fibrosis Idiopathic Pulmonary Fibrosis, Pulmonary, Idiopathic Hamman-Rich Syndrome Chronic Idiopathic Pulmonary Fibrosis Acute Interstitial Pneumonia Interstitial Pulmonary Fibrosis Ipf - [Idiopathic Pulmonary Fibrosis] Idiopathic Lung Fibrosis Fibrosing Lung Disease Pulmonary Fibrosis Nos Fibrosing Pneumonitis
Leukemia, Acute Myeloid	Acute Myeloid Leukemia Leukemia, Acute Myelogenous Acute Myelogenous Leukemia AML Leukemia, Acute Myeloid, Susceptibility To Acute Myeloblastic Leukemia Leukemia, Acute Myeloid, Reduced Survival In, Somatic Acute Myeloid Leukaemia Leukemia, Myelocytic, Acute Therapy Related Acute Myeloid Leukemia And Myelodysplastic Syndrome Secondary Aml Acute Myelocytic Leukemia Acute Myeloid Leukemia, Somatic Leukemia, Acute Myeloid, Somatic Myeloid Leukemia, Acute, M4/M4eo Subtype, Somatic Acute Myeloblastic Leukaemia Acute Myelogenous Leukaemia Aml - Acute Myeloid Leukemia Acute Myeloid Leukemia With Cebpa Somatic Mutations Aml With Cebpa Somatic Mutations Inherited Acute Myeloid Leukemia Familial Aml Inherited Aml Pure Familial Aml Pure Familial Acute Myeloid Leukemia Secondary Acute Myeloid Leukemia Therapy-Related Aml And Myelodysplastic Syndrome Acute Myeloid Leukemia, Secondary Acute Non-Lymphoblastic Leukemia Acute Non-Lymphocytic Leukemia Acute Biphenotypic Leukemia Acute Undifferentiated Leukemia Acute Myeloblastic Leukaemia With Multilineage Dysplasia Acute Myeloid Leukaemia With Multilineage Dysplasia Without Mention Of Remission Acute Myeloid Leukaemia With Myelodysplasia-Related Features
Nervous System Disease	Abnormality Of The Nervous System Nervous System Diseases Nervous System Disorder

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Clinical Phase
Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Phase
HY-10456	TAK-715		99.76%	Phase 2

Pre-clinical Phase

Bioactive Molecules (4)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS13470	SNAI1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-P5291	CPF-7		/	Unkown
HY-RS19742	Snai1 Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS26238	Snai1 Rat Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	SNAI1	VGNC	VGNC:46584
Felis catus	SNAI1	VGNC	VGNC:65514
Bos taurus	SNAI1	VGNC	VGNC:35047
Rattus norvegicus	SNAI1	RGD	RGD:620758
Mus musculus	SNAI1	MGD	MGI:98330
Others	SNAI1	NCBI